[1] Liu Y, Gao Y, Zhan X, et al. TLR4 activation by lipopolysaccharide and Streptococcus mutans induces differential regulation of proliferation and migration in human dental pulp stem cells. J Endod. 2014;40(9):1375-1381.[2] 麻丹丹,高杰,吴补领.改良组织块酶消化法培养人龋损牙髓干细胞的实验研究[J].牙体牙髓牙周病学杂志, 2011,21(7):371-374.[3] Gronthos S, Mankani M, Brahim J, et al. Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. Proc Natl AcadSci U S A. 2000;97(25):13625-13630.[4] Arthur A, Rychkov G, Shi S, et al. Adult human dental pulp stem cells differentiate toward functionally active neurons under appropriate environmental cues. Stem Cells. 2008;26(7):1787-1795.[5] Kim JK, Baker J, Nor JE, et al. mTor plays an important role in odontoblast differentiation. J Endod. 2011;37(8):1081-1085.[6] 刘影,高杰,吴补领. 改良组织块酶消化法原代培养人牙髓干细胞的研究[J].口腔疾病防治,2018,26(3):166-170.[7] Nam S, Won JE, Kim CH, et al. Odontogenic differentiation of human dental pulp stem cells stimulated by the calcium phosphate porous granules. J Tissue Eng. 2011;2011:812547.[8] Ma D, Gao J, Yue J, et al. Changes in proliferation and osteogenic differentiation of stem cells from deep caries in vitro. J Endod. 2012;38(6):796-802.[9] Gronthos S, Brahim J, Li W, et al. Stem cell properties of human dental pulp stem cells. J Dent Res. 2002;81(8):531-535.[10] Wang CY, Tani-Ishii N, Stashenko P. Bone-resorptive cytokine gene expression in periapical lesions in the rat. Oral MicrobiolImmunol. 1997;12(2):65-71.[11] 刘影,高岩,文军,徐帅妹.TLR4在健康和深龋人牙髓组织中的定位表达[J].口腔疾病防治,2017,25(3):158-163.[12] Horst OV, Tompkins KA, Coats SR, et al. TGF-beta1 Inhibits TLR-mediated odontoblast responses to oral bacteria. J Dent Res. 2009;88(4):333-338.[13] Okada M, Soda Y, Hayashi F, et al. PCR detection of Streptococcus mutans and S. sobrinus in dental plaque samples from Japanese pre-school children. J Med Microbiol. 2002;51(5): 443-447.[14] Jiang HW, Zhang W, Ren BP, et al. Expression of toll like receptor 4 in normal human odontoblasts and dental pulp tissue. J Endod. 2006;32(8):747-751.[15] Mutoh N, Tani-Ishii N, Tsukinoki K, et al. Expression of toll-like receptor 2 and 4 in dental pulp. J Endod. 2007;33(10):1183-1186.[16] Wang CY, Tani-Ishii N, Stashenko P. Bone-resorptive cytokine gene expression in periapical lesions in the rat. Oral MicrobiolImmunol. 1997;12(2):65-71.[17] Rutherford RB, Gu K. Treatment of inflamed ferret dental pulps with recombinant bone morphogenetic protein-7. Eur J Oral Sci. 2000;108(3):202-206.[18] Hu H, Li Z, Zhu X, et al. Gua Lou GuiZhi decoction suppresses LPS-induced activation of the TLR4/NF-κB pathway in BV-2 murine microglial cells. Int J Mol Med. 2013;31(6):1327-1332.[19] He W, Qu T, Yu Q, et al. LPS induces IL-8 expression through TLR4, MyD88, NF-kappaB and MAPK pathways in human dental pulp stem cells. IntEndod J. 2013;46(2):128-136.[20] Zhang J, Zhang Y, Lv H, et al. Human stem cells from the apical papilla response to bacterial lipopolysaccharide exposure and anti-inflammatory effects of nuclear factor I C. J Endod. 2013; 39(11):1416-1422.[21] Medvedev AE, Kopydlowski KM, Vogel SN. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin- tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression. J Immunol. 2000;164(11):5564-5574.[22] Papp T, Hollo K, Meszar-Katona E, et al. TLR signalling can modify the mineralization of tooth germ. ActaOdontol Scand. 2016; 74(4):307-314.[23] Li JG, Lin JJ, Wang ZL, et al. Melatonin attenuates inflammation of acute pulpitis subjected to dental pulp injury. Am J Transl Res. 2015;7(1):66-78.[24] Rachmawati D, Peferoen LA, Vogel DY, et al. Metal ions potentiate microglia responsiveness to endotoxin. J Neuroimmunol. 2016; 291:89-95.[25] 岳静,高杰,徐树军,等.变形链球菌超声提取物对牙髓细胞增殖和天然免疫受体基因 mRNA表达的影响[J].实用口腔医学杂志, 2013, 29(1):16-19.[26] Kesavalu L, Lucas AR, Verma RK, et al. Increased atherogenesis during Streptococcus mutans infection in ApoE-null mice. J Dent Res. 2012;91(3):255-260.[27] Hirao K, Yumoto H, Takahashi K, et al. Roles of TLR2, TLR4, NOD2, and NOD1 in pulp fibroblasts. J Dent Res. 2009;88(8): 762-767.[28] He W, Wang Z, Luo Z, et al. LPS promote the odontoblastic differentiation of human dental pulp stem cells via MAPK signaling pathway. J Cell Physiol. 2015;230(3):554-561.[29] Levin LG, Rudd A, Bletsa A, et al. Expression of IL-8 by cells of the odontoblast layer in vitro. Eur J Oral Sci.1999;107(2): 131-137.[30] Nagaoka S, Tokuda M, Sakuta T, et al. Interleukin-8 gene expression by human dental pulp fibroblast in cultures stimulated with Prevotella intermedia lipopolysaccharide. J Endod. 1996; 22(1):9-12.[31] Otsuka M, Okinaga T, Ariyoshi W, et al. Ameloblastin Upregulates Inflammatory Response Through Induction of IL-1β in Human Macrophages. J Cell Biochem. 2017;118(10):3308-3317.[32] Botero TM, Son JS, Vodopyanov D, et al. MAPK signaling is required for LPS-induced VEGF in pulp stem cells. J Dent Res. 2010;89(3):264-269.[33] Sun DG, Xin BC, Wu D, et al. miR-140-5p-mediated regulation of the proliferation and differentiation of human dental pulp stem cells occurs through the lipopolysaccharide/toll-like receptor 4 signaling pathway. Eur J Oral Sci. 2017;125(6):419-425.[34] Lawrence H, Mawdesley AE, Holland JP, et al. Targeting Toll-like receptor 4 prevents cobalt-mediated inflammation. Oncotarget. 2016;7(7):7578-7585.[35] Papp T, Hollo K, Meszar-Katona E, et al. TLR signalling can modify the mineralization of tooth germ. ActaOdontol Scand. 2016;74(4):307-314. |