中国组织工程研究 ›› 2018, Vol. 22 ›› Issue (7): 1133-1139.doi: 10.3969/j.issn.2095-4344.0129

• 骨与关节综述 bone and joint review • 上一篇    下一篇

股骨头坏死的精准医疗:概念与模式

周明旺1,邓 昶2,李盛华1,付志斌1   

  1. 1甘肃省中医院,甘肃省兰州市 730050;2甘肃中医药大学,甘肃省兰州市 730000
  • 出版日期:2018-03-08 发布日期:2018-03-08
  • 通讯作者: 李盛华,硕士,主任医师,教授,博士生导师,甘肃省中医院,甘肃省兰州市 730050
  • 作者简介:周明旺,1977年生,甘肃省兰州市人,汉族,2013年天津中医药大学毕业,博士,副主任医师,主要从事中医药防治骨关节疾病的研究。
  • 基金资助:

    国家自然科学基金(81473712/H2710);甘肃省卫生行业科研计划项目(GSWSKY-2015-13);甘肃陇原青年人才创新扶持计划

Precision medicine of osteonecrosis of the femoral head: concepts and patterns

Zhou Ming-wang1, Deng Chang2, Li Sheng-hua1, Fu Zhi-bin1   

  1. 1Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, Gansu Province, China; 2Gansu University of Chinese Medicine, Lanzhou 730000, Gansu Province, China
  • Online:2018-03-08 Published:2018-03-08
  • Contact: Li Sheng-hua, Master, Chief physician, Professor, Doctoral supervisor, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, Gansu Province, China
  • About author:Zhou Ming-wang, M.D., Associate chief physician, Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, Gansu Province, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81473712/H2710; the Gansu Provincial Health Industry Research Plan Project, No. GSWSKY-2015-13; the Youth Talent Innovation Support Plan of Gansu Province

摘要:

文章快速阅读:

 
 
文题释义:
精准医疗:是以个体化医疗为基础,对疾病和特定患者进行个性化精准治疗的新型医学概念与医疗模式,核心关键词在于“个性化医疗”双侧半棘肌:半棘肌位干棘肌的深面,按部位又分为头、颈、背半棘肌。作者认为在股骨头坏死的防治研究中,3D打印技术、计算机辅助导航技术、精准微创骨科技术、基因研究及治疗等技术正是实现精准化、个性化医疗的有效手段。
精准微创骨科:是指通过运用计算机技术为患者制定个性化手术方案,以最小的侵袭和最小的生理干扰达到最佳疗效的一种新技术,具有手术切口小、组织损伤少、精确率高、疗效肯定、术后恢复时间短等特点。
 
摘要
背景:近年来,精准医疗已经成为当今医学界的热门话题,精准医疗在股骨头坏死中的应用也越来越广泛。
目的:总结目前精准医疗在股骨头坏死中的研究现状及进展。
方法:以“精准医疗,股骨头坏死,3D打印,计算机辅助导航,微创,基因”为中文检索词,以“precision medicine,osteonecrosis of the femoral head,3D printing,computer assisted navigation,minimal invasive,gene”为英文检索词,在中国知网和PubMed数据库检索近10年国内外关于精准医疗在股骨头坏死中应用的相关文献。
结果与结论:①在股骨头坏死的防治研究中,3D打印技术、计算机辅助导航技术、精准微创骨科技术、基因研究及治疗等技术正是实现精准化、个性化医疗的有效手段;②精准医疗这一新的医学模式的出现,丰富了股骨头坏死的治疗手段,提高了股骨头坏死的治疗效果,给广大患者带来了新的曙光,给从事股骨头坏死临床与基础研究的医学工作者、科研人员提供了新的思路和启发。

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程
ORCID: 0000-0001-7853-3112(周明旺)

关键词: 精准医疗, 股骨头坏死, 3D打印, 计算机辅助导航, 微创, 基因, 国家自然科学基金

Abstract:

BACKGROUND: In recent years, precision medicine has become a hot topic in the medical field. The application of precision medicine to osteonecrosis of the femoral head is wider than before.

OBJECTIVE: To summarize the current status and progress of precision medicine to osteonecrosis of the femoral head.
METHODS: A computer-based search of PubMed and CNKI databases was performed for literatures about application and prospect of precision medicine for osteonecrosis of the femoral head in and outside China published within the past 10 years using the keywords of “precision medicine, osteonecrosis of the femoral head, three dimensional (3D) printing, computer assisted navigation, minimal invasive, gene” in English and Chinese.
RESULTS AND CONCLUSION: (1) In the study on the prevention and treatment of osteonecrosis of the femoral head, 3D printing technology, computer assisted navigation technology, precision minimally invasive orthopedic technology, research and treatment of gene are four effective ways to achieve precise and personalized healthcare. (2) The appearance of precision medicine, a novel medicinal model, enriches the treatment of osteonecrosis of the femoral head and enhances the curative efficacy of the disease. It brings the new dawn to the patient and provides some new clues for medical workers and researchers engaged in the clinical and basic researches of osteonecrosis of the femoral head.

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱骨折;内固定;数字化骨科;组织工程

Key words: Surgical Procedures, Minimally Invasive, Osteonecrosis of the femoral head, Review, Tissue Engineering

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