中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (3): 488-491.doi: 10.3969/j.issn.1673-8225.2010.03.026

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

脱细胞生物敷料在烧伤创面的应用：106例150个创面结局验证

李华强   

  1. 开封市第一人民医院烧伤整形科，开封市烧伤整形研究所，河南省开封市  475000
  • 出版日期:2010-01-15 发布日期:2010-01-15
  • 作者简介:李华强，男，1965生，河南省新郑市人，汉族，2003年武汉科技大学毕业，副主任医师，主要从事烧伤创面覆盖材料的研究。 Kfyylhq@126com

Clinical application of acellular biological dressing in burn wound: Outcomes of 106 patients with 150 wounds

Li Hua-qiang   

  1. Department of Burn and Plastic Surgery, Kaifeng First People’s Hospital, Institute of Burn and Plastic Surgery, Kaifeng  475000, Henan Province, China
  • Online:2010-01-15 Published:2010-01-15
  • About author:Li Hua-qiang, Associate chief physician, Department of Burn and Plastic Surgery, Kaifeng First People’s Hospital, Institute of Burn and Plastic Surgery, Kaifeng 475000, Henan Province, China Kfyylhq@126com

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摘要：

目的：评价不同类型创面应用脱细胞生物敷料的效果。
方法：将脱细胞生物敷料用于106例烧伤患者150个创面。供皮区创面84个，浅Ⅱ度创面30个，深Ⅱ度创面16个，Ⅲ度创面10个，自体植皮间隙创面5个，后期残余小创面5个。分别在手术取皮后、清创后、植皮间隙后立即用脱细胞生物敷料覆盖干纱布包扎。
结果：在150个不同类型创面中，未黏附4个(2.67%)均为Ⅲ度创面，感染2个(1.3%)均为后期残余小创面，渗出物显著积聚而需更换4个(2.67%)均为深Ⅱ度创面。其他创面黏附好，无感染，渗血少，疼痛明显减轻。
结论：脱细胞生物敷料用于供皮区创面、浅Ⅱ度及深Ⅱ度新鲜创面、自体植皮间隙创面效果满意。

关键词: 脱细胞生物敷料, 烧伤创面, 供皮区创面, 效果, 生物材料

Abstract:

OBJECTIVE: To evaluate the application of different types of wound dressing acellular biological effect.
METHODS: The acellular biological dressing was used in the 106 cases of 150 burn wounds. There were 84 donor site wounds, 30 Ⅱ degree superficial and 16 deep Ⅱ degree of fresh wounds, 10 Ⅲ degree burn wounds, 5 surgical wounds in the lack of space in autologous skin grafting, and 5 latter part of the small residual wounds. Acellular biological dressing with the covering of dry gauze bandage was used immediately after the surgery to take skin, debridement, and dermoplasty clearance separately.
RESULTS: Among 150 wounds, 4 non-adherent wounds (2.67%) were Ⅲ degree wounds. Infected 2 wounds (1.3%) were latter part of the small residual wounds. Significant accumulation of exudation required 4 (2.67%) deep Ⅱ degree fresh wounds. Other wounds presented good adherence, no infection, less capillary hemorrhage, and significant relief of pain.
CONCLUSION: The acellular biological dressing for skin graft donor site wounds, superficial and deep Ⅱdegree fresh wounds, wounds with autologous skin grafting gap results were satisfactory.

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