中国组织工程研究

中国组织工程研究 ›› 2024, Vol. 28 ›› Issue (23): 3692-3698.doi: 10.12307/2024.418

• 组织工程相关大数据分析 Big data analysis in tissue engineering • 上一篇    下一篇

缺血性脑卒中与血管再生的前沿热点分析

夏天晴1，戎梦玮1，但存燕1，杨  婷2，丁智斌2，宋丽娟1，3，马存根1   

  1. 1山西中医药大学国家中医药管理局多发性硬化益气活血重点研究室/神经生物学研究中心，山西省晋中市  030619；2山西医科大学第三医院(山西白求恩医院，山西医学科学院，同济山西医院)神经内科，山西省太原市  030032；3国药同煤集团总医院神经外科，山西省大同市  037003
  • 收稿日期:2023-06-01 接受日期:2023-07-20 出版日期:2024-08-18 发布日期:2023-09-13
  • 通讯作者: 马存根，博士，教授，博士生导师，山西中医药大学国家中医药管理局多发性硬化益气活血重点研究室/神经生物学研究中心，山西省晋中市 030619
  • 作者简介:夏天晴，女，1996年生，天津市人，汉族，山西中医药大学在读硕士，主要从事中西医结合与脑血管疾病研究。
  • 基金资助:
    国家自然科学基金项目(82004028)，项目负责人：宋丽娟；国家自然科学基金项目(81473577)，项目负责人：马存根；中国博士后科学基金面上资助项目(2020M680912)，项目负责人：宋丽娟；国家中医药管理局“张仲景传承与创新专项”(GZY-KJS-2022-048-1)，项目负责人：宋丽娟；山西省科技创新人才青年团队项目(202204051001028)，项目负责人：宋丽娟；山西中医药大学2022年度科技创新团队项目(2022TD2010)，项目负责人：马存根、宋丽娟；山西省卫健委医学科技领军团队项目(2020TD05)，项目负责人：马存根；山西中医药大学附属医院国家区域中医医疗中心心血管专项基金项目(XGZX202115)，项目负责人：宋丽娟；山西中医药大学青年科学家培育项目(2021PY-QN-09)，项目负责人：宋丽娟；山西中医药大学学科建设经费(2023XKJS-02)，项目负责人：马存根

Frontier hot trends in ischemic stroke and vascular regeneration based on bibliometric analysis

Xia Tianqing1, Rong Mengwei1, Dan Cunyan1, Yang Ting2, Ding Zhibin2, Song Lijuan1, 3, Ma Cungen1   

  1. 1The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine/Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong 030619, Shandong Province, China; 2Department of Neurology, Third Hospital of Shanxi Medical University (Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital), Taiyuan 030032, Shanxi Province, China; 3Department of Neurosurgery, Sinopharm Tongmei General Hospital, Datong 037003, Shanxi Province, China
  • Received:2023-06-01 Accepted:2023-07-20 Online:2024-08-18 Published:2023-09-13
  • Contact: Ma Cungen, MD, Professor, Doctoral supervisor, The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine/Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong 030619, Shandong Province, China
  • About author:Xia Tianqing, Master candidate, The Key Research Laboratory of Benefiting Qi for Acting Blood Circulation Method to Treat Multiple Sclerosis of State Administration of Traditional Chinese Medicine/Research Center of Neurobiology, Shanxi University of Chinese Medicine, Jinzhong 030619, Shandong Province, China
  • Supported by:
    the National Natural Science Foundation of China, Nos. 82004028 (to SLJ) and 81473577 (to MCG); China Postdoctoral Science Foundation, No. 2020M680912 (to SLJ); “Zhang Zhongjing Inheritance and Innovation Special Project” of the National Administration of Traditional Chinese Medicine, No. GZY-KJS-2022-048-1 (to SLJ); Shanxi Provincial Science and Technology Innovative Talent Young Team Project, No. 202204051001028 (to SLJ); Shanxi University of Chinese Medicine 2022 Scientific and Technological Innovation Team Project, No. 2022TD2010 (to MCG and SLJ); Medical Science and Technology Leading Team Project of Shanxi Provincial Health Commission, No. 2020TD05 (to MCG); National Regional TCM Medical Center Cardiovascular Special Fund for Shanxi University of Chinese Medicine Affiliated Hospital, No. XGZX202115 (to SLJ); Shanxi University of Chinese Medicine Young Scientist Cultivation Project, No. 2021PY-QN-09 (to SLJ); Shanxi University of Chinese Medicine Discipline Construction Fund, No. 2023XKJS-02 (to MCG)

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摘要：


文题释义：

文献计量学：是以各类文献为基础，采用数学、计算机科学、系统科学的方法对文献规律、文献科学管理及科学技术动态与特征进行研究的一门科学。
缺血性脑卒中：又称脑梗死，是各种原因导致脑动脉血流中断，局部脑组织缺氧、缺血性坏死而出现相应神经功能缺损的脑血管疾病。


背景：血管再生为缺血性脑卒中发病后重要的修复过程之一，因此二者之间的可视化分析极其必要。

目的：基于文献计量学分析近10年来缺血性脑卒中与血管再生研究的相关文献，梳理该领域的研究现状、热点及未来发展趋势。
方法：应用文献计量学方法，检索Web of Science(WoS)数据库2011年1月至2023年5月期间缺血性脑卒中与血管再生的相关文献，获取的数据采用可视化软件VOSviewer从发文量、国家、关键词、机构、作者、引文、关键词等方面进行系统分析。

结果与结论：经过检索筛选出了1 484篇文章，发现缺血性脑卒中和血管再生之间的关系已成为了脑血管领域内新兴的研究热点，发文量持续上升。其中大多发文机构来自于中国与美国，文章被引用次数最高的机构是上海交通大学，最有影响力的作者是HERMANN DM，他的文章被引用了1 003次，而细胞外囊泡、microRNA、间质干细胞与疾病之间的关系是这一领域内的研究热点。通过文献计量学分析为缺血性脑卒中及血管再生领域提供了可视化分析，发现此领域将是一个新兴的焦点，同时也为缺血性脑卒中和血管再生的研究要点和未来趋势提供了有益参考。

https://orcid.org/0009-0002-6397-9722(夏天晴)

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

关键词: 缺血性脑卒中, 血管再生, 文献计量学, VOSviewer, 脑血管疾病

Abstract: BACKGROUND: Vascular regeneration, as one of the crucial repair processes after its onset, necessitates visual analysis between the two.
OBJECTIVE: To analyze the literature on ischemic stroke and vascular regeneration in the past decade using bibliometrics and sort out the current status, hotspots, and future research trends in this field. 
METHODS: We used a bibliometric approach to search the Web of Science database for literature on ischemic stroke and vascular regeneration published between January 2011 and May 2023. The obtained data were systematically analyzed using the VOSviewer visualization software to identify the number of articles, countries, keywords, institutions, authors, citations, and trends.
RESULTS AND CONCLUSION: We searched and selected 1 484 articles and found that the relationship between ischemic stroke and vascular regeneration has emerged as a research hotspot in the cerebrovascular field, with the number of published articles continuing to rise. Most of these articles were authored by institutions from China and the United States. Shanghai Jiao Tong University was the most cited institution. The most influential author was Hermann DM, whose article had been cited 1 003 times. The current hot research topics in the field include extracellular vesicles, microRNAs and mesenchymal stem cells, which are being studied for their correlations with relevant diseases. To conclude, the bibliometric analysis provides a visual analysis of ischemic stroke and vascular regeneration, which is found to be an emerging focus as well as a valuable reference for future trends and highlights in ischemic stroke and vascular regeneration.

Key words: ischemic stroke, vascular regeneration, bibliometric analysis, VOSviewer, cerebrovascular disease

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