中国组织工程研究

中国组织工程研究 ›› 2015, Vol. 19 ›› Issue (12): 1904-1908.doi: 10.3969/j.issn.2095-4344.2015.12.019

• 细胞外基质材料 extracellular matrix materials • 上一篇    下一篇

硅胶材料隆乳对人体口腔黏膜细胞状态的影响

丁艳美   

  1. 天水市中西医结合医院口腔科，甘肃省天水市  741020
  • 修回日期:2015-02-05 出版日期:2015-03-19 发布日期:2015-03-19
  • 作者简介:丁艳美，女，1974年生，甘肃省天水市人，汉族，2010年兰州大学毕业，主治医师。

Silicone materials for breast augmentation influence the state of human oral mucosa cells

Ding Yan-mei   

  1. Department of Stomatology, Tianshui Hospital of Integrative Medicine, Tianshui 741020, Gansu Province, China
  • Revised:2015-02-05 Online:2015-03-19 Published:2015-03-19
  • About author:Ding Yan-mei, Attending physician, Department of Stomatology, Tianshui Hospital of Integrative Medicine, Tianshui 741020, Gansu Province, China

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453

被引次数

1

摘要：

背景：既往研究显示，口腔黏膜细胞的生存状态直接受人体营养状态的影响，因此可能是外科营养状态的良好指标，但该指标是否同样会受到外科手术创伤刺激影响这一问题的答案尚不明确。
目的：观察硅胶隆乳相关外科创伤性刺激对口腔黏膜细胞生存状态的影响。
方法：选择拟行硅胶隆乳的女性患者32例，其中有生育史13例，无生育史19例，年龄23-45岁，分别采用亚G1峰法及Ki-67法于硅胶隆乳前后检测患者口腔黏膜细胞的增殖率及凋亡率，对数据进行统计学比较。
结果与结论：32例硅胶隆乳者均顺利完成手术，围术期未发生严重不良反应。32例硅胶隆乳患者隆乳前口腔黏膜细胞凋亡率及增殖率分别为(27.3±6.2)%与(27.8±5.8)%，隆乳后口腔黏膜细胞凋亡率及增殖率分别为(27.8±5.8)%与(20.2±7.7)%，隆乳前后口腔黏膜细胞凋亡率及增殖率比较差异均无显著性意义(P > 0.05)。表明人体口腔黏膜细胞的增殖及凋亡并未受到硅胶隆乳相关外科创伤的明显影响，口腔黏膜细胞生存状态用于硅胶隆乳受者营养状态的评估可能具有一定的价值。


中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程


全文链接：

关键词: 生物材料, 材料相容性, 硅胶隆乳, 口腔黏膜细胞, 外科创伤, 亚G1峰法, Ki-67

Abstract:

BACKGROUND: Previous studies have shown that the survival state of oral mucosal cells directly is directly affected by the nutritional status of the body, therefore, it may be a good indicator of the surgical nutritional status. But whether this index also influences surgical trauma stimulus is still unclear.
OBJECTIVE: To observe the effect of breast augmentation with silicone implants on the survival status of oral mucosal cells.
METHODS: Thirty-two female patients scheduled for breast augmentation with silicone implants, including 13 cases of reproductive history and 19 cases of non-reproductive history, aged 23-45 years old. Sub-G1 peak method and Ki-67 were used to detect the proliferation and apoptosis rates of oral mucosa cells before and after breast augmentation with silicone implants for statistical comparisons.
RESULTS AND CONCLUSION: All the 32 cases successfully completed breast augmentation with silicone implants, and no serious adverse events occurred perioperatively. The oral mucosa cell apoptosis and proliferation rates were (27.3±6.2)% and (27.8±5.8)% before breast augmentation, and (27.8±5.8)% and (20.2±7.7)% after breast augmentation. There was no difference before and after breast augmentation (P > 0.05). These findings indicate that the proliferation and apoptosis of human oral mucosa cells cannot be significantly by breast augmentation-related trauma, and the survival state of oral mucosa cells has some value to assess the nutritional state of breast augmentation recipients.


中国组织工程研究杂志出版内容重点：生物材料；骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性；组织工程


全文链接：

Key words: Silica Gel, Cell Proliferation, Apoptosis

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