关键词: 腕关节, 韧带, 损伤, 支架, 康复, 生物材料, 组织工程

Abstract:

OBJECTIVE: To investigate the wrist ligament injury and selection of ligament stent using artificial biomaterials.
METHODS: The PubMed database and CNKI database were retrieved on computer, by screening key words of “wrist joint, ligament, injury, stent” in English and in Chinese in the titles and abstracts. Articles related to wrist ligament injury and treatment, characteristics of materials science, biocompatibility and its application effect were included, those published recently or published in national core journals were preferred in the same field, ultimately 18 articles were involved.
RESULTS: The synthetic absorbable scaffold materials may be used as a prosthetic ligament to replace the injured tendon or ligament. LARS artificial ligament imitates the anatomical structure and biomechanical characteristics of the human body, with good resistance to fatigue and not easy to induce inflammation. Treatment of tendon autograft ligament achieves excellent effect for dynamic scapholunate interosseous separation, but poor effect for static scapholunate separation, biological artificial ligament finished product is similar to normal tendon appearance, with flexible texture, reaches a pre-conceived requirement.
CONCLUSION: The excellent biocompatibility and resistance to fatigue are essential for the selection of ligament tendon scaffolds, LARS artificial ligament is an ideal graft material, but more suitable for acute ligament injury patients. Ligament tendon autograft is difficult to select. Biological artificial ligament is effective to treat the wrist ligament injury. Cell and molecular biology techniques as well as the use of gene therapy will become a new direction in the treatment of wrist ligament injury and rehabilitation.