[1] SHARIATI A, NEMATI R, SADEGHIPOUR Y, et al. Mesenchymal stromal cells (MSCs) for neurodegenerative disease: A promising frontier. Eur J Cell Biol. 2020;99(6):151097.
[2] DJAJADIKERTA A, KESHRI S, PAVEL M, et al. Autophagy Induction as a Therapeutic Strategy for Neurodegenerative Diseases. J Mol Biol. 2020;432(8):2799-2821.
[3] CECCARIGLIA S, CARGNONI A, SILINI AR, et al. Autophagy: a potential key contributor to the therapeutic action of mesenchymal stem cells. Autophagy. 2020;16(1):28-37.
[4] PARK H, KANG JH, LEE S. Autophagy in Neurodegenerative Diseases: A Hunter for Aggregates. Int J Mol Sci. 2020;21(9):3369.
[5] GRIFFEY CJ, YAMAMOTO A. Macroautophagy in CNS health and disease. Nat Rev Neurosci. 2022;23(7):411-427.
[6] ABDRAKHMANOV A, GOGVADZE V, ZHIVOTOVSKY B. To Eat or to Die: Deciphering Selective Forms of Autophagy. Trends Biochem Sci. 2020;45(4):347-364.
[7] KAUSHIK S, CUERVO AM. The coming of age of chaperone-mediated autophagy. Nat Rev Mol Cell Biol. 2018;19(6):365-381.
[8] GALLUZZI L, GREEN DR. Autophagy-Independent Functions of the Autophagy Machinery. Cell. 2019;177(7):1682-1699.
[9] NNAH IC, WANG B, SAQCENA C, et al. TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy. Autophagy. 2019;15(1):151-164.
[10] NAKATOGAWA H. Two ubiquitin-like conjugation systems that mediate membrane formation during autophagy. Essays Biochem. 2013;55:39-50.
[11] LŐRINCZ P, JUHÁSZ G. Autophagosome-Lysosome Fusion. J Mol Biol. 2020;432(8): 2462-2482.
[12] SCHUCK S. Microautophagy - distinct molecular mechanisms handle cargoes of many sizes. J Cell Sci. 2020;133(17):jcs246322.
[13] LIAO Z, WANG B, LIU W, et al. Dysfunction of chaperone-mediated autophagy in human diseases. Mol Cell Biochem. 2021;476(3):1439-1454.
[14] NAKATOGAWA H. Mechanisms governing autophagosome biogenesis. Nat Rev Mol Cell Biol. 2020;21(8):439-458.
[15] OKOLICSANYI RK, CAMILLERI ET, OIKARI LE, et al. Human Mesenchymal Stem Cells Retain Multilineage Differentiation Capacity Including Neural Marker Expression after Extended In Vitro Expansion. PLoS One. 2015;10(9):e0137255.
[16] NAJI A, EITOKU M, FAVIER B, et al. Biological functions of mesenchymal stem cells and clinical implications. Cell Mol Life Sci. 2019;76(17):3323-3348.
[17] XIAO C, LU D, CHEN J, et al. Human Olfactory Mesenchymal Stem Cells Are a Novel Candidate for Neurological Autoimmune Disease. Front Pharmacol. 2021; 12:770884.
[18] WANG B, LIU XM, LIU ZN, et al. Human hair follicle-derived mesenchymal stem cells: Isolation, expansion, and differentiation. World J Stem Cells. 2020;12(6): 462-470.
[19] ZHUO Y, WANG L, GE L, et al. Hypoxic Culture Promotes Dopaminergic-Neuronal Differentiation of Nasal Olfactory Mucosa Mesenchymal Stem Cells via Upregulation of Hypoxia-Inducible Factor-1α. Cell Transplant. 2017;26(8):1452-1461.
[20] SUMARWOTO T, SUROTO H, MAHYUDIN F, et al. Role of adipose mesenchymal stem cells and secretome in peripheral nerve regeneration. Ann Med Surg (Lond). 2021;67:102482.
[21] CONE AS, YUAN X, SUN L, et al. Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer’s disease-like phenotypes in a preclinical mouse model. Theranostics. 2021;11(17):8129-8142.
[22] HU C, LI L. Preconditioning influences mesenchymal stem cell properties in vitro and in vivo. J Cell Mol Med. 2018;22(3):1428-1442.
[23] LIU Y, WANG N, ZHANG S, et al. Autophagy protects bone marrow mesenchymal stem cells from palmitate‑induced apoptosis through the ROS‑JNK/p38 MAPK signaling pathways. Mol Med Rep. 2018;18(2):1485-1494.
[24] LI ZH, WANG YL, WANG HJ, et al. Rapamycin-Preactivated Autophagy Enhances Survival and Differentiation of Mesenchymal Stem Cells After Transplantation into Infarcted Myocardium. Stem Cell Rev Rep. 2020;16(2):344-356.
[25] MA Y, QI M, AN Y, et al. Autophagy controls mesenchymal stem cell properties and senescence during bone aging. Aging Cell. 2018;17(1):e12709.
[26] LIU ZZ, HONG CG, HU WB, et al. Autophagy receptor OPTN (optineurin) regulates mesenchymal stem cell fate and bone-fat balance during aging by clearing FABP3. Autophagy. 2021;17(10):2766-2782.
[27] LI W, LI K, GAO J, et al. Autophagy is required for human umbilical cord mesenchymal stem cells to improve spatial working memory in APP/PS1 transgenic mouse model. Stem Cell Res Ther. 2018;9(1):9.
[28] CEN S, WANG P, XIE Z, et al. Autophagy enhances mesenchymal stem cell-mediated CD4+ T cell migration and differentiation through CXCL8 and TGF-β1. Stem Cell Res Ther. 2019;10(1):265.
[29] BERGMANN CA, BELTRAN S, VEGA-LETTER AM, et al. The Autophagy Protein Pacer Positively Regulates the Therapeutic Potential of Mesenchymal Stem Cells in a Mouse Model of DSS-Induced Colitis. Cells. 2022;11(9):1503.
[30] WANG HY, LI C, LIU WH, et al. Autophagy inhibition via Becn1 downregulation improves the mesenchymal stem cells antifibrotic potential in experimental liver fibrosis. J Cell Physiol. 2020;235(3):2722-2737.
[31] DANG S, XU H, XU C, et al. Autophagy regulates the therapeutic potential of mesenchymal stem cells in experimental autoimmune encephalomyelitis. Autophagy. 2014;10(7):1301-1315.
[32] KULKARNI A, CHEN J, MADAY S. Neuronal autophagy and intercellular regulation of homeostasis in the brain. Curr Opin Neurobiol. 2018;51:29-36.
[33] LEVINE B, KROEMER G. Biological Functions of Autophagy Genes: A Disease Perspective. Cell. 2019;176(1-2):11-42.
[34] SUMITOMO A, TOMODA T. Autophagy in neuronal physiology and disease. Curr Opin Pharmacol. 2021;60:133-140.
[35] KUMA A, KOMATSU M, MIZUSHIMA N. Autophagy-monitoring and autophagy-deficient mice. Autophagy. 2017;13(10):1619-1628.
[36] KUIJPERS M, KOCHLAMAZASHVILI G, STUMPF A, et al. Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum. Neuron. 2021;109(2):299-313.e9.
[37] DI MALTA C, FRYER JD, SETTEMBRE C, et al. Astrocyte dysfunction triggers neurodegeneration in a lysosomal storage disorder. Proc Natl Acad Sci U S A. 2012;109(35):E2334-E2342.
[38] XU Y, PROPSON NE, DU S, et al. Autophagy deficiency modulates microglial lipid homeostasis and aggravates tau pathology and spreading. Proc Natl Acad Sci U S A. 2021;118(27):e2023418118.
[39] HOUTMAN J, FREITAG K, GIMBER N, et al. Beclin1-driven autophagy modulates the inflammatory response of microglia via NLRP3. EMBO J. 2019;38(4):e99430.
[40] YAZDANKHAH M, GHOSH S, SHANG P, et al. BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes. Autophagy. 2021;17(10):3140-3159.
[41] STAVOE AK, GOPAL PP, GUBAS A, et al. Expression of WIPI2B counteracts age-related decline in autophagosome biogenesis in neurons. Elife. 2019;8:e44219.
[42] RAHMAN MA, RHIM H. Therapeutic implication of autophagy in neurodegenerative diseases. BMB Rep. 2017;50(7):345-354.
[43] TU HY, YUAN BS, HOU XO, et al. α-synuclein suppresses microglial autophagy and promotes neurodegeneration in a mouse model of Parkinson’s disease. Aging Cell. 2021;20(12):e13522.
[44] HOFFMANN AC, MINAKAKI G, MENGES S, et al. Extracellular aggregated alpha synuclein primarily triggers lysosomal dysfunction in neural cells prevented by trehalose. Sci Rep. 2019;9(1):544.
[45] FRANCO-IBORRA S, PLAZA-ZABALA A, MONTPEYO M, et al. Mutant HTT (huntingtin) impairs mitophagy in a cellular model of Huntington disease. Autophagy. 2021;17(3):672-689.
[46] HO PW, LEUNG CT, LIU H, et al. Age-dependent accumulation of oligomeric SNCA/α-synuclein from impaired degradation in mutant LRRK2 knockin mouse model of Parkinson disease: role for therapeutic activation of chaperone-mediated autophagy (CMA). Autophagy. 2020;16(2):347-370.
[47] CHONG CM, KE M, TAN Y, et al. Presenilin 1 deficiency suppresses autophagy in human neural stem cells through reducing γ-secretase-independent ERK/CREB signaling. Cell Death Dis. 2018;9(9):879.
[48] DENG Z, PURTELL K, LACHANCE V, et al. Autophagy Receptors and Neurodegenerative Diseases. Trends Cell Biol. 2017;27(7):491-504.
[49] SHIN JY, PARK HJ, KIM HN, et al. Mesenchymal stem cells enhance autophagy and increase β-amyloid clearance in Alzheimer disease models. Autophagy. 2014;10(1):32-44.
[50] XU Z, NAN W, ZHANG X, et al. Umbilical Cord Mesenchymal Stem Cells Conditioned Medium Promotes Aβ25-35 phagocytosis by Modulating Autophagy and Aβ-Degrading Enzymes in BV2 Cells. J Mol Neurosci. 2018;65(2):222-233.
[51] PARK HJ, SHIN JY, KIM HN, et al. Neuroprotective effects of mesenchymal stem cells through autophagy modulation in a parkinsonian model. Neurobiol Aging. 2014;35(8):1920-1928.
[52] OH SH, LEE SC, KIM DY, et al. Mesenchymal Stem Cells Stabilize Axonal Transports for Autophagic Clearance of α-Synuclein in Parkinsonian Models. Stem Cells. 2017;35(8):1934-1947.
[53] BAI X, DONG Q, ZHAO L, et al. microRNA-106b-containing extracellular vesicles affect autophagy of neurons by regulating CDKN2B in Parkinson’s disease. Neurosci Lett. 2021;760:136094.
[54] LI Q, WANG Z, XING H, et al. Exosomes derived from miR-188-3p-modified adipose-derived mesenchymal stem cells protect Parkinson’s disease. Mol Ther Nucleic Acids. 2021;23:1334-1344.
[55] ŘEHOŘOVÁ M, VARGOVÁ I, FOROSTYAK S, et al. A Combination of Intrathecal and Intramuscular Application of Human Mesenchymal Stem Cells Partly Reduces the Activation of Necroptosis in the Spinal Cord of SOD1G93A Rats. Stem Cells Transl Med. 2019;8(6):535-547.
[56] LUO F, SANDHU AF, RUNGRATANAWANICH W, et al. Melatonin and Autophagy in Aging-Related Neurodegenerative Diseases. Int J Mol Sci. 2020;21(19):7174.
[57] KIM DY, CHOI SH, LEE JS, et al. Feasibility and Efficacy of Intra-Arterial Administration of Embryonic Stem Cell Derived-Mesenchymal Stem Cells in Animal Model of Alzheimer’s Disease. J Alzheimers Dis. 2020;76(4):1281-1296.
[58] ABOZAID OAR, SALLAM MW, AHMED ESA. Mesenchymal Stem Cells Modulate SIRT1/MiR-134/ GSK3β Signaling Pathway in a Rat Model of Alzheimer’s Disease. J Prev Alzheimers Dis. 2022;9(3):458-468.
[59] CHEN HX, LIANG FC, GU P, et al. Exosomes derived from mesenchymal stem cells repair a Parkinson’s disease model by inducing autophagy. Cell Death Dis. 2020;11(4):288.
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