中国组织工程研究 ›› 2024, Vol. 28 ›› Issue (12): 1849-1854.doi: 10.12307/2024.071

• 骨与关节生物力学 bone and joint biomechanics • 上一篇    下一篇

有限元模拟单通道分体内镜下双侧腰椎管减压对腰椎生物力学的影响

张景贺,窦永峰,许世东,邢建强,刘  栋,田  霖,戴国华   

  1. 滨州医学院附属医院,山东省滨州市   256600
  • 收稿日期:2023-03-15 接受日期:2023-05-20 出版日期:2024-04-28 发布日期:2023-08-22
  • 通讯作者: 窦永峰,硕士,主任医师,滨州医学院附属医院,山东省滨州市 256600
  • 作者简介:张景贺,男,1994年生,河北省沧州市人,汉族,滨州医学院在读硕士,主要从事脊柱外科方向研究。
  • 基金资助:
    山东省高等学校科技计划项目(J14LL51),项目负责人:窦永峰

Effect of finite element simulation of bilateral lumbar spinal canal decompression under single-channel splintered endoscope on lumbar biomechanics

Zhang Jinghe, Dou Yongfeng, Xu Shidong, Xing Jianqiang, Liu Dong, Tian Lin, Dai Guohua   

  1. Affiliated Hospital of Binzhou Medical University, Binzhou 256600, Shandong Province, China
  • Received:2023-03-15 Accepted:2023-05-20 Online:2024-04-28 Published:2023-08-22
  • Contact: Dou Yongfeng, Master, Chief physician, Affiliated Hospital of Binzhou Medical University, Binzhou 256600, Shandong Province, China
  • About author:Zhang Jinghe, Master candidate, Affiliated Hospital of Binzhou Medical University, Binzhou 256600, Shandong Province, China
  • Supported by:
    Shandong Province Higher Education Science and Technology Plan Project, No. J14LL51 (to DYF)

摘要:


文题释义:

单通道分体内镜技术:为脊柱内镜发展的新兴入路方式,可在较小创伤下完成骨性椎管、神经根管以及侧隐窝扩大成形,小切口下改善神经根以及硬膜囊压迫,缓解患者症状,改善患者生活质量。
后侧入路脊柱内镜下单侧入路双侧减压:脊柱内镜通过水介质来获得较清晰视野,相对开放手术创伤较小、安全性及精确性更高,首先进行单侧减压,然后通过over-the-top技术进行对侧减压,主要适用于中央管狭窄以及存在双侧侧隐窝狭窄患者。


背景:单通道分体内镜技术单侧入路双侧减压手术作为后侧入路脊柱内镜下治疗椎管狭窄症的前沿技术,远期疗效有待进一步观察,对术中切除范围的研究少有报道,且目前鲜有生物力学以及有限元分析的相关研究报道。

目的:通过建立三维有限元模型评估单通道分体内镜下双侧腰椎管减压对腰椎活动度和椎间盘内压力的影响,为临床手术提供建议,为进一步临床研究提供理论基础。
方法:通过9名健康志愿者CT图像重建完整的L3-L5椎体模型,作为术前模型M1,对L4-L5进行模拟手术切除,分别切除双侧关节突关节1/4,1/3,1/2,获得模型M2、M3、M4。在前屈、后伸、左右弯曲、左右旋转6个不同方向比较4个模型的关节活动度和纤维环应力(Von Mises)最大值。

结果与结论:①此研究建立的L3-L5有限元模型具有较好的仿真性和可靠性,在6个活动状态下关节活动度处于以往实体研究的区间范围内;②与M1模型比较,M2、M3、M4模型L4-L5腰椎活动度在前倾、左右弯曲、左右旋转载荷下随着切除范围增大而增大,差异有显著性意义(P < 0.05);在后伸载荷下,M1与M2的腰椎活动度比较差异无显著性意义(P > 0.05),但M1与M3、M4比较差异有显著性意义(P < 0.05);③L3-L4腰椎活动度随着双侧关节突关节切除范围增大无明显变化,差异无显著性意义(P > 0.05);④M1与M2的L4-L5腰椎Von Mises最大值比较,差异有显著性意义(P < 0.05),M1与M3、M4比较,差异有显著性意义(P < 0.01),L4-L5腰椎Von Mises最大值随着双侧关节突关节切除范围增大而增大,切除1/3以上尤为明显;⑤L3-L4腰椎Von Mises最大值在前倾、左右弯曲、左右旋转载荷下,随着切除范围增大而增大,差异有显著性意义(P < 0.05);⑥结果表明:L4-L5节段腰椎活动度及椎间盘内压力随着切除范围的增大而增大;L3-L4节段椎间盘内压力随着切除范围的增大而增大,但腰椎活动度未见明显影响。由此可见,随着关节突关节切除范围增加,可能影响手术节段稳定性,相邻节段虽近期稳定性影响不大,但可能加速椎间盘退变。

https://orcid.org/0009-0004-9996-4287 (张景贺) 

中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程

关键词: 脊柱内镜, 腰椎后路减压, 生物力学, 有限元分析, 腰椎管狭窄症

Abstract: BACKGROUND: As a leading technique in the treatment of primary stenosis by posterior spinal endoscopy through unilateral approach and bilateral decompression using single channel endoscopy, the long-term efficacy needs to be further observed. There are few reports on the scope of intraoperative resection and few relevant studies on biomechanics and finite element analysis.
OBJECTIVE: A three-dimensional finite element model was established to evaluate the effects of bilateral lumbar canal decompression under a one-hole split endoscope on lumbar range of motion and intradiscal pressure, to provide suggestions for clinical operation and theoretical basis for further clinical research.
METHODS: A complete L3-L5 vertebral body model was reconstructed by CT images of nine healthy volunteers, which was used as the preoperative model M1. The simulated surgical resection range of L4-L5 was performed, and 1/4, 1/3 and 1/2 of bilateral facet joints were removed respectively to obtain models M2, M3 and M4. The range of motion and the maximum Von Mises stress of the four models were compared in the six directions of forward bending, backward extension, left and right bending, and left and right rotation.
RESULTS AND CONCLUSION: (1) The L3-L5 finite element model established in this study was effective, and the range of motion was within the range of previous solid studies under six motion states. (2) Compared with the M1 model, the L4-L5 lumbar spine range of motion increased with the increase of resection range in M2 with M3 and M4 models under forward bending, left and right bending and left and right rotation loading, and the difference was significant (P < 0.05). Under posterior extension loading, there was no significant difference in lumbar range of motion between M1 and M2 (P > 0.05), but there was a significant difference of M1, M3 and M4 (P < 0.05). (3) The range of motion of the L3-L4 lumbar spine had no significant change with the increase of bilateral facet arthrotomy (P > 0.05). (4) There was a significant difference in the maximum value of L4-L5 Von Mises between M1 and M2 (P < 0.05), and there was a significant difference in the maximum value of L4-L5 Von Mises between M1 and M3, M4 (P < 0.01), and the maximum value of L4-L5 lumbar von Mises increased with the increasing range of bilateral facet joint resection. Resection of more than 1/3 was particularly obvious. (5) The maximum value of Von Mises in the L3-L4 lumbar spine was increased with the increase of the resection range under forward bending, left and right bending and left and right rotation loading and the difference was significant (P < 0.05). (6) The results exhibited that the L4-L5 lumbar motion and intervertebral disc pressure increased with the increase of the excision range. Intervertebral disc pressure at L3-L4 increased with the increased extent of excision, but the lumbar range of motion was not significantly affected. In conclusion, the stability of the operative segment may be affected by the increase in the scope of facet joint resection. Although the immediate stability of adjacent segments is not affected, it may accelerate disc degeneration.

Key words: spinal endoscopy, lumbar posterior decompression, biomechanics, finite element analysis, lumbar spinal stenosis

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