[1] ARORA R, CHAWLA R, MARWAH R, et al. Medical radiation countermeasures for nuclear and radiological emergencies: Current status and future perspectives. J Pharm Bioallied Sci. 2010;2(3):202-212.
[2] WILLIAMS JP, BROWN SL, GEORGES GE, et al. Animal models for medical countermeasures to radiation exposure. Radiat Res. 2010;173(4):557-578.
[3] KOUKOURAKIS MI. Radiation damage and radioprotectants: new concepts in the era of molecular medicine. Br J Radiol. 2012;85(1012):313-330.
[4] HAARER J, JOHNSON CL, SOEDER Y, et al. Caveats of mesenchymal stem cell therapy in solid organ transplantation. Transpl Int. 2015;28(1):1-9.
[5] RAHGOSHAI S, MOHAMMADI M, REFAHI S, et al. Protective Effects of IMOD and Cimetidine against Radiation-induced Cellular Damage. J Biomed Phys Eng. 2018;8(1):133-140.
[6] SATYAMITRA M, KUMAR VP, BISWAS S, et al. Impact of Abbreviated Filgrastim Schedule on Survival and Hematopoietic Recovery after Irradiation in Four Mouse Strains with Different Radiosensitivity. Radiat Res. 2017;187(6):659-671.
[7] 王芳敏,熊国林,申星,等.重组人干细胞因子对重症急性放射病猴的治疗作用研究[J].中国实验血液学杂志,2017,25(5):1544-1549.
[8] NICOLAY NH, LOPEZ PEREZ R, SAFFRICH R, et al. Radio-resistant mesenchymal stem cells: mechanisms of resistance and potential implications for the clinic. Oncotarget. 2015;6(23):19366-19380.
[9] WEN S, DOONER M, CHENG Y, et al. Mesenchymal stromal cell-derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells. Leukemia. 2016;30(11):2221-2231.
[10] NICOLAY NH, LIANG Y, LOPEZ PEREZ R, et al. Mesenchymal stem cells are resistant to carbon ion radiotherapy. Oncotarget. 2015;6(4):2076-2087.
[11] BERNARDO ME, COMETA AM, LOCATELLI F. Mesenchymal stromal cells: a novel and effective strategy for facilitating engraftment and accelerating hematopoietic recovery after transplantation? Bone Marrow Transplant. 2012;47(3):323-329.
[12] CHAPEL A, FRANCOIS S, DOUAY L, et al. Fifteen years of preclinical and clinical experiences about biotherapy treatment of lesions induced by accidental irradiation and radiotherapy. World J Stem Cells. 2013;5(3):68-72.
[13] NICOLAY NH, LOPEZ PEREZ R, DEBUS J, et al. Mesenchymal stem cells – A new hope for radiotherapy-induced tissue damage? Cancer Lett. 2015;366(2): 133-140.
[14] CLANCY JW, SEDGWICK A, ROSSE C, et al. Regulated delivery of molecular cargo to invasive tumour-derived microvesicles. Nat Commun. 2015;6:6919.
[15] URKASEMSIN G, FERREIRA JN. Unveiling Stem Cell Heterogeneity Toward the Development of Salivary Gland Regenerative Strategies. Adv Exp Med Biol. 2019; 1123:151-164.
[16] CRESCITELLI R, LÄSSER C, JANG SC, et al. Subpopulations of extracellular vesicles from human metastatic melanoma tissue identified by quantitative proteomics after optimized isolation. J Extracell Vesicles. 2020;9(1):1722433.
[17] THAN UTT, GUANZON D, LEAVESLEY D, et al. Association of Extracellular Membrane Vesicles with Cutaneous Wound Healing. Int J Mol Sci. 2017;18(5):956.
[18] BEBELMAN MP, SMIT MJ, PEGTEL DM, et al. Biogenesis and function of extracellular vesicles in cancer. Pharmacol Ther. 2018;188:1-11.
[19] GURUNATHAN S, KANG MH, JEYARAJ M, et al. Review of the Isolation, Characterization, Biological Function, and Multifarious Therapeutic Approaches of Exosomes. Cells. 2019;8(4):307.
[20] WILHELM EN, GONZÁLEZ-ALONSO J, PARRIS C, et al. Exercise intensity modulates the appearance of circulating microvesicles with proangiogenic potential upon endothelial cells. Am J Physiol Heart Circ Physiol. 2016;311(5):H1297-H1310.
[21] ZÖLLER M. Tetraspanins: push and pull in suppressing and promoting metastasis. Nat Rev Cancer. 2009;9(1):40-55.
[22] MORELLO M, MINCIACCHI VR, DE CANDIA P, et al. Large oncosomes mediate intercellular transfer of functional microRNA. Cell Cycle. 2013;12(22):3526-3536.
[23] KALLURI R, LEBLEU VS. The biology, function, and biomedical applications of exosomes. Science. 2020;367(6478):eaau6977.
[24] ESCREVENTE C, KELLER S, ALTEVOGT P, et al. Interaction and uptake of exosomes by ovarian cancer cells. BMC Cancer. 2011;11:108.
[25] CARUSO S, POON IKH. Apoptotic Cell-Derived Extracellular Vesicles: More Than Just Debris. Front Immunol. 2018;9:1486.
[26] BRUNO S, KHOLIA S, DEREGIBUS MC, et al. The Role of Extracellular Vesicles as Paracrine Effectors in Stem Cell-Based Therapies. Adv Exp Med Biol. 2019; 1201:175-193.
[27] MENON R. Initiation of human parturition: signaling from senescent fetal tissues via extracellular vesicle mediated paracrine mechanism. Obstet Gynecol Sci. 2019;62(4):199-211.
[28] YAMAMOTO T, KOSAKA N, OCHIYA T. Latest advances in extracellular vesicles: from bench to bedside. Sci Technol Adv Mater. 2019;20(1):746-757.
[29] VEGA VL, RODRÍGUEZ-SILVA M, FREY T, et al. Hsp70 translocates into the plasma membrane after stress and is released into the extracellular environment in a membrane-associated form that activates macrophages. J Immunol. 2008; 180(6):4299-4307.
[30] DOYLE LM, WANG MZ. Overview of Extracellular Vesicles, Their Origin, Composition, Purpose, and Methods for Exosome Isolation and Analysis. Cells. 2019;8(7):727.
[31] HECKMANN M, DOUWES K, PETER R, et al. Vascular activation of adhesion molecule mRNA and cell surface expression by ionizing radiation. Exp Cell Res. 1998;238(1):148-154.
[32] LANGLEY RE, BUMP EA, QUARTUCCIO SG, et al. Radiation-induced apoptosis in microvascular endothelial cells. Br J Cancer. 1997;75(5):666-672.
[33] WANG J, BOERMA M, FU Q, et al. Significance of endothelial dysfunction in the pathogenesis of early and delayed radiation enteropathy. World J Gastroenterol. 2007;13(22):3047-3055.
[34] BAKER DG, KROCHAK RJ. The response of the microvascular system to radiation: a review. Cancer Invest. 1989;7(3):287-294.
[35] GOLDIN-LANG P, NIEBERGALL F, ANTONIAK S, et al. Ionizing radiation induces upregulation of cellular procoagulability and tissue factor expression in human peripheral blood mononuclear cells. Thromb Res. 2007;120(6):857-864.
[36] FORLOW SB, MCEVER RP, NOLLERT MU. Leukocyte-leukocyte interactions mediated by platelet microparticles under flow. Blood. 2000;95(4):1317-1323.
[37] HUBER J, VALES A, MITULOVIC G, et al. Oxidized membrane vesicles and blebs from apoptotic cells contain biologically active oxidized phospholipids that induce monocyte-endothelial interactions. Arterioscler Thromb Vasc Biol. 2002; 22(1):101-107.
[38] FLAMANT S, TAMARAT R. Extracellular Vesicles and Vascular Injury: New Insights for Radiation Exposure. Radiat Res. 2016;186(2):203-218.
[39] SZATMÁRI T, HARGITAI R, SÁFRÁNY G, et al. Extracellular Vesicles in Modifying the Effects of Ionizing Radiation. Int J Mol Sci. 2019;20(22):5527.
[40] NIKITAKI Z, MAVRAGANI IV, LASKARATOU DA, et al. Systemic mechanisms and effects of ionizing radiation: A new ‘old’ paradigm of how the bystanders and distant can become the players. Semin Cancer Biol. 2016;37-38:77-95.
[41] SZATMÁRI T, KIS D, BOGDÁNDI EN, et al. Extracellular Vesicles Mediate Radiation-Induced Systemic Bystander Signals in the Bone Marrow and Spleen. Front Immunol. 2017;8:347.
[42] RASTOGI S, HWANG A, CHAN J, et al. Extracellular vesicles transfer nuclear Abl-dependent and radiation-induced miR-34c into unirradiated cells to cause bystander effects. Mol Biol Cell. 2018;29(18):2228-2242.
[43] ARSCOTT WT, TANDLE AT, ZHAO S, et al. Ionizing radiation and glioblastoma exosomes: implications in tumor biology and cell migration. Transl Oncol. 2013; 6(6):638-648.
[44] AL-MAYAH A, BRIGHT S, CHAPMAN K, et al. The non-targeted effects of radiation are perpetuated by exosomes. Mutat Res. 2015;772:38-45.
[45] MO LJ, SONG M, HUANG QH, et al. Exosome-packaged miR-1246 contributes to bystander DNA damage by targeting LIG4. Br J Cancer. 2018;119(4):492-502.
[46] ARIYOSHI K, MIURA T, KASAI K, et al. Radiation-Induced Bystander Effect is Mediated by Mitochondrial DNA in Exosome-Like Vesicles. Sci Rep. 2019;9(1): 9103.
[47] BODEGA G, ALIQUE M, PUEBLA L, et al. Microvesicles: ROS scavengers and ROS producers. J Extracell Vesicles. 2019;8(1):1626654.
[48] ZUO R, LIU M, WANG Y, et al. BM-MSC-derived exosomes alleviate radiation-induced bone loss by restoring the function of recipient BM-MSCs and activating Wnt/β-catenin signaling. Stem Cell Res Ther. 2019;10(1):30.
[49] ZHANG J, HAN X, ZHAO Y, et al. Mouse serum protects against total body irradiation-induced hematopoietic system injury by improving the systemic environment after radiation. Free Radic Biol Med. 2019;131:382-392.
[50] DENG M , YU Z , LI D , et al. Human umbilical cord mesenchymal stem cell-derived and dermal fibroblast-derived extracellular vesicles protect dermal fibroblasts from ultraviolet radiation-induced photoaging in vitro. Photochem Photobiol Sci. 2020;19(3):406-414.
[51] MOERTL S, BUSCHMANN D, AZIMZADEH O, et al. Radiation Exposure of Peripheral Mononuclear Blood Cells Alters the Composition and Function of Secreted Extracellular Vesicles. Int J Mol Sci. 2020;21(7):2336.
[52] HEIDER T, MUTSCHELKNAUS L, RADULOVIĆ V, et al. Radiation induced transcriptional and post-transcriptional regulation of the hsa-miR-23a~27a~24-2 cluster suppresses apoptosis by stabilizing XIAP. Biochim Biophys Acta Gene Regul Mech. 2017;1860(11):1127-1137.
[53] ZHAO S, LI J, ZHANG G, et al. Exosomal miR-451a Functions as a Tumor Suppressor in Hepatocellular Carcinoma by Targeting LPIN1. Cell Physiol Biochem. 2019;53(1):19-35.
[54] KIM JH, LEE DK, KIM J, et al. A miRNA-101-3p/Bim axis as a determinant of serum deprivation-induced endothelial cell apoptosis. Cell Death Dis. 2017;8(5):e2808.
[55] BAULCH JE, ACHARYA MM, ALLEN BD, et al. Cranial grafting of stem cell-derived microvesicles improves cognition and reduces neuropathology in the irradiated brain. Proc Natl Acad Sci U S A. 2016;113(17):4836-4841.
[56] SMITH SM, GIEDZINSKI E, ANGULO MC, et al. Functional equivalence of stem cell and stem cell-derived extracellular vesicle transplantation to repair the irradiated brain. Stem Cells Transl Med. 2020;9(1):93-105.
[57] ACHARYA MM, ROSI S, JOPSON T, et al. Human neural stem cell transplantation provides long-term restoration of neuronal plasticity in the irradiated hippocampus. Cell Transplant. 2015;24(4):691-702.
[58] LIU Z, CAO K, LIAO Z, et al. Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes. J Cell Mol Med. 2020;24(7): 3917-3930.
[59] KINK JA, FORSBERG MH, RESHETYLO S, et al. Macrophages Educated with Exosomes from Primed Mesenchymal Stem Cells Treat Acute Radiation Syndrome by Promoting Hematopoietic Recovery. Biol Blood Marrow Transplant. 2019;25(11):2124-2133.
[60] PIRYANI SO, JIAO Y, KAM AYF, et al. Endothelial Cell-Derived Extracellular Vesicles Mitigate Radiation-Induced Hematopoietic Injury. Int J Radiat Oncol Biol Phys. 2019;104(2):291-301.
[61] SAHA S, ARANDA E, HAYAKAWA Y, et al. Macrophage-derived extracellular vesicle-packaged WNTs rescue intestinal stem cells and enhance survival after radiation injury. Nat Commun. 2016;7:13096.
|