中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (48): 9074-9077.doi: 10.3969/j.issn.1673-8225.2011.48.036

• 骨与关节学术探讨 academic discussion of the bone and joint • 上一篇    下一篇

假体置换、植骨内固定及骨水泥填充治疗骨巨细胞瘤

广  东，王亚军，赵  凡   

  1. 吉林大学第二医院骨科，吉林省吉林市  130021 
  • 收稿日期:2011-07-26 修回日期:2011-10-17 出版日期:2011-11-26 发布日期:2011-11-26
  • 通讯作者: 王亚军，硕士，主任医师，硕士研究生导师，吉林大学第二医院骨科，吉林省吉林市 130021 wangyajun@163.com
  • 作者简介:广东★，男，1981年生，黑龙江省大庆市人，汉族，吉林大学在读硕士，主要从事四肢关节创伤及骨肿瘤方面的研究。 guangdong888@163.com

Prosthesis, bone graft and internal fixation and bone cement filling for treatment of giant cell tumor of bone

Guang Dong, Wang Ya-jun, Zhao Fan   

  1. Department of Orthopedics, Second Hospital of Jilin University, Jilin  130021, Jilin Province, China
  • Received:2011-07-26 Revised:2011-10-17 Online:2011-11-26 Published:2011-11-26
  • Contact: Wang Ya-jun, Master, Chief physician, Master’s supervisor, Department of Orthopedics, Second Hospital of Jilin University, Jilin 130021, Jilin Province, China wangyajun@163.com
  • About author:Guang Dong★, Studying for master’s degree, Department of Orthopedics, Second Hospital of Jilin University, Jilin 130021, Jilin Province, China guangdong888@163.com

PDF

431

被引次数

9

摘要：

背景：人工关节置换或同种异体骨内固定及骨组织替代材料填充是修复骨巨细胞瘤刮除后骨缺损的常见方式，那么哪一种更理想呢？
目的：通过查阅关于骨巨细胞瘤治疗方面的中英文文献，了解骨巨细胞瘤的分期标准并比较以植骨内固定、骨水泥填充及假体置换为主的治疗方法。
方法：中国知网数据库输入中文检索词“肿瘤型假体，骨巨细胞瘤，植骨内固定，骨水泥”， Elesvier Science和Springer-Link 数据库输入英文检索词“giant cell tumor of bone、therapy 、tumor-type prosthesis”，纳入与骨巨细胞瘤人工假体置换、植骨内固定及骨水泥填充治疗骨巨细胞瘤的相关文献，共检索到346篇文献。保留26篇做进一步分析。
结果与结论：传统的骨巨细胞瘤治疗方法相对复发率较高，刮骨植骨时植骨量不一定能够充填满整个骨腔，骨水泥材料又不容易融合吸收，在众多治疗方法当中肿瘤型假体显示出了良好的效果，但尚有不足，而特制假体置换根据关节部位缺损需要能够个体化的治疗骨巨细胞瘤，是一种疗效可靠的手术方法，也是未来治疗骨巨细胞瘤的主要研究方向。

关键词: 骨巨细胞瘤, 植骨, 肿瘤型假体, 骨水泥, 治疗, 综述

Abstract:

BACKGROUND: Artificial joint replacement or allogeneic bone fixation and bone substitute materials filling are common ways to repair bone defects in giant cell tumor of bone after curettage, so which one is more ideal?
OBJECTIVE: To understand the staging standard of giant cell tumors through access to Chinese and English literature about treatment for giant cell tumor of bone, and to compare different therapies, bone graft, bone cement filling and prosthesis.
METHODS: A computer based search of CNKI using keywords of “tumor-type prosthesis, giant cell tumor of bone, bone graft, bone cement” and Elsevier Science and Pringer-Link using keywords of “giant cell tumor of bone, therapy, tumor-type prosthesis” were performed to retrieve relevant articles. Totally 346 articles were retrieved, and finally 26 were included in result analysis.
RESULTS AND CONCLUSION: The traditional treatments for giant cell tumor have a higher recurrence rate. The bone graft may not be able to fill the entire bone cavity, bone cement materials cannot be easy to be fused with the host. Tumor-type prosthesis shows a good effect on giant cell tumor of bone, but it is still inadequate. However, special prosthesis joints can repair bone defects following giant cell tumor of bone according to individualized treatment needs, which is an effective and reliable surgical method as well as the main research direction for the future treatment of giant cell tumor of bone.

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