[1] ZHANG YL, YIN JH, DING H, et al. Vitamin K2 Prevents Glucocorticoid-induced Osteonecrosis of the Femoral Head in Rats. Int J Biol Sci. 2016; 12(4):347-358.
[2] ZHANG Y, YIN J, DING H, et al. Vitamin K2 Ameliorates Damage of Blood Vessels by Glucocorticoid: a Potential Mechanism for Its Protective Effects in Glucocorticoid-induced Osteonecrosis of the Femoral Head in a Rat Model. Int J Biol Sci. 2016;12(7):776-785.
[3] HAO C, YANG S, XU W, et al. MiR-708 promotes steroid-induced osteonecrosis of femoral head, suppresses osteogenic differentiation by targeting SMAD3. Sci Rep. 2016;6:22599.
[4] YOUM YS, LEE SY, LEE SH. Apoptosis in the osteonecrosis of the femoral head. Clin Orthop Surg. 2010;2(4):250-255.
[5] ZHU Y, ZHOU J, AO R, et al. A-769662 protects osteoblasts from hydrogen dioxide-induced apoptosis through activating of AMP-activated protein kinase (AMPK). Int J Mol Sci. 2014;15(6): 11190-11203.
[6] WEINSTEIN RS, WAN C, LIU Q, et al. Endogenous glucocorticoids decrease skeletal angiogenesis, vascularity, hydration, and strength in aged mice. Aging Cell. 2010;9(2):147-161.
[7] LIU D, ZHANG Y, LI X, et al. eIF2α signaling regulates ischemic osteonecrosis through endoplasmic reticulum stress. Sci Rep. 2017; 7(1):5062.
[8] HUGHES A, OXFORD AE, TAWARA K, et al. Endoplasmic reticulum stress and unfolded protein response in cartilage pathophysiology; contributing factors to apoptosis and osteoarthritis. Int J Mol Sci. 2017; 18(3):665.
[9] CHUNG CY, KHURANA V, AULUCK PK, et al. Identification and rescue of α-synuclein toxicity in Parkinson patient-derived neurons. Science. 2013;342(6161):983-987.
[10] SATO AY, TU X, MCANDREWS KA, et al. Prevention of glucocorticoid induced-apoptosis of osteoblasts and osteocytes by protecting against endoplasmic reticulum (ER) stress in vitro and in vivo in female mice. Bone. 2015;73:60-68.
[11] LISSE TS, THIELE F, FUCHS H, et al. ER stress-mediated apoptosis in a new mouse model of osteogenesis imperfecta. PLoS Genet. 2008;4(2): e7.
[12] BINET F, SAPIEHA P. ER Stress and Angiogenesis. Cell Metab. 2015; 22(4):560-575.
[13] PARK S H, BLACKSTONE C. Further assembly required: construction and dynamics of the endoplasmic reticulum network. EMBO Rep. 2010; 11(7):515-521.
[14] VAN MEER G, VOELKER DR, FEIGENSON GW. Membrane lipids: where they are and how they behave. Nat Rev Mol Cell Biol. 2008;9(2): 112-124.
[15] FEWELL SW, TRAVERS KJ, WEISSMAN JS, et al. The action of molecular chaperones in the early secretory pathway. Annu Rev Genet. 2001;35: 149-191.
[16] ELLGAARD L, HELENIUS A. Quality control in the endoplasmic reticulum. Nat Rev Mol Cell Biol. 2003;4(3):181-191.
[17] BERRIDGE MJ. The endoplasmic reticulum: a multifunctional signaling organelle. Cell Calcium. 2002;32(5-6):235-249.
[18] ARAKI K, NAGATA K. Protein folding and quality control in the ER. Cold Spring Harb Perspect Biol. 2011;3(11):a007526.
[19] BERTOLOTTI A, ZHANG Y, HENDERSHOT LM, et al. Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol. 2000;2(6):326-232.
[20] LEE AS. The glucose-regulated proteins: stress induction and clinical applications. Trends Biochem Sci. 2001;26(8):504-510.
[21] ELETTO D, DERSH D, ARGON Y. GRP94 in ER quality control and stress responses. Semin Cell Dev Biol. 2010;21(5):479-485.
[22] XU Y, GUO M, JIANG W, et al. Endoplasmic reticulum stress and its effects on renal tubular cells apoptosis in ischemic acute kidney injury. Ren Fail. 2016;38(5):831-837.
[23] WANG M, KAUFMAN RJ. Protein misfolding in the endoplasmic reticulum as a conduit to human disease. Nature. 2016;529(7586): 326-335.
[24] DICKHOUT JG, CARLISLE RE, AUSTIN RC. Interrelationship between cardiac hypertrophy, heart failure, and chronic kidney disease: endoplasmic reticulum stress as a mediator of pathogenesis. Circ Res. 2011;108(5):629-642.
[25] DICKHOUT JG, KREPINSKY JC. Endoplasmic reticulum stress and renal disease. Antioxid Redox Signal. 2009;11(9):2341-2352.
[26] GALLOT YS, BOHNERT KR, STRAUGHN AR, et al. PERK regulates skeletal muscle mass and contractile function in adult mice. FASEB J. 2019; 33(2):1946-1962.
[27] ROZPEDEK W, PYTEL D, MUCHA B, et al. The Role of the PERK/eIF2α/ATF4/CHOP Signaling Pathway in Tumor Progression During Endoplasmic Reticulum Stress. Curr Mol Med. 2016;16(6):533-544.
[28] KANG X, YANG W, WANG R, et al. Sirtuin-1 (SIRT1) stimulates growth-plate chondrogenesis by attenuating the PERK-eIF-2α-CHOP pathway in the unfolded protein response. J Biol Chem. 2018;293(22):8614-8625.
[29] AMIN-WETZEL N, SAUNDERS RA, KAMPHUIS MJ, et al. A J-Protein Co-chaperone Recruits BiP to Monomerize IRE1 and Repress the Unfolded Protein Response. Cell. 2017;171(7):1625-1637.e13.
[30] SALAROGLIO IC, PANADA E, MOISO E, et al. PERK induces resistance to cell death elicited by endoplasmic reticulum stress and chemotherapy. Mol Cancer. 2017;16(1):91.
[31] TANG JY, JIN P, HE Q, et al. Naringenin ameliorates hypoxia/reoxygenation-induced endoplasmic reticulum stress-mediated apoptosis in H9c2 myocardial cells: involvement in ATF6, IRE1α and PERK signaling activation. Mol Cell Biochem. 2017;424(1-2):111-122.
[32] HUGHES D, MALLUCCI GR. The unfolded protein response in neurodegenerative disorders - therapeutic modulation of the PERK pathway. FEBS J. 2019;286(2):342-355.
[33] JIANG D, TAM AB, ALAGAPPAN M, et al. Acridine Derivatives as Inhibitors of the IRE1α-XBP1 Pathway Are Cytotoxic to Human Multiple Myeloma. Mol Cancer Ther. 2016;15(9):2055-2065.
[34] ROJAS-RIVERA D, RODRIGUEZ DA, SEPULVEDA D, et al. ER stress sensing mechanism: Putting off the brake on UPR transducers. Oncotarget. 2018;9(28):19461-19462.
[35] GUO Y, LIN D, ZHANG M, et al. CLDN6-induced apoptosis via regulating ASK1-p38/JNK signaling in breast cancer MCF-7 cells. Int J Oncol. 2016; 48(6):2435-2444.
[36] SUN L, ZHANG SS, LU SJ, et al. Site-1 protease cleavage site is important for the ER stress-induced activation of membrane-associated transcription factor bZIP28 in Arabidopsis. Sci China Life Sci. 2015; 58(3):270-275.
[37] ZHOU T, LV X, GUO X, et al. RACK1 modulates apoptosis induced by sorafenib in HCC cells by interfering with the IRE1/XBP1 axis. Oncol Rep. 2015;33(6):3006-3014.
[38] HUANG Y, LENG TD, INOUE K, et al. TRPM7 channels play a role in high glucose-induced endoplasmic reticulum stress and neuronal cell apoptosis. J Biol Chem. 2018;293(37):14393-14406.
[39] CHEN N, DAI L, JIANG Y, et al. Endoplasmic reticulum stress intolerance in EIF2B3 mutant oligodendrocytes is modulated by depressed autophagy. Brain Dev. 2016;38(5):507-515.
[40] LI H, CHEN H, LI R, et al. Cucurbitacin I induces cancer cell death through the endoplasmic reticulum stress pathway. J Cell Biochem. 2018 Sep 11. doi: 10.1002/jcb.27570.
[41] ZHAO ZQ, BAI R, LIU WL, et al. Roles of oxidative DNA damage of bone marrow hematopoietic cells in steroid-induced avascular necrosis of femoral head. Genet Mol Res. 2016;15(1). doi: 10.4238/gmr.15017706.
[42] BAI R, NA Y, LIU W, et al. Quantitative assessment of ABCB1 polymorphisms and non-traumatic osteonecrosis of the femur head risk. 2016;9:21542-21548.
[43] XIE Y, YE S, ZHANG J, et al. Protective effect of mild endoplasmic reticulum stress on radiation-induced bystander effects in hepatocyte cells. Sci Rep. 2016;6:38832.
[44] KEMTER E, FRÖHLICH T, ARNOLD GJ, et al. Mitochondrial Dysregulation Secondary to Endoplasmic Reticulum Stress in Autosomal Dominant Tubulointerstitial Kidney Disease - UMOD (ADTKD-UMOD). Sci Rep. 2017;7:42970.
[45] SHI J, WANG L, ZHANG H, et al. Glucocorticoids: Dose-related effects on osteoclast formation and function via reactive oxygen species and autophagy. Bone. 2015;79:222-232.
[46] HE M, WANG J, WANG G, et al. Effect of glucocorticoids on osteoclast function in a mouse model of bone necrosis. Mol Med Rep. 2016; 14(2):1054-1060.
[47] ZOU W, YANG S, ZHANG T, et al. Hypoxia enhances glucocorticoid-induced apoptosis and cell cycle arrest via the PI3K/Akt signaling pathway in osteoblastic cells. J Bone Miner Metab. 2015;33(6): 615-624.
[48] STENBECK G, COXON FP. Role of vesicular trafficking in skeletal dynamics. Curr Opin Pharmacol. 2014;16:7-14.
[49] DESELM CJ, MILLER BC, ZOU W, et al. Autophagy proteins regulate the secretory component of osteoclastic bone resorption. Dev Cell. 2011; 21(5):966-974.
[50] HARA T, TAKAMURA A, KISHI C, et al. FIP200, a ULK-interacting protein, is required for autophagosome formation in mammalian cells. J Cell Biol. 2008;181(3):497-510.
[51] LIU F, FANG F, YUAN H, et al. Suppression of autophagy by FIP200 deletion leads to osteopenia in mice through the inhibition of osteoblast terminal differentiation. J Bone Miner Res. 2013;28(11): 2414-2430.
[52] STENBECK G. Formation and function of the ruffled border in osteoclasts. Semin Cell Dev Biol. 2002;13(4):285-292.
[53] LEE HK, MATTEI LM, STEINBERG BE, et al. In vivo requirement for Atg5 in antigen presentation by dendritic cells. Immunity. 2010;32(2): 227-239.
[54] LUO P, GAO F, HAN J, et al. The role of autophagy in steroid necrosis of the femoral head: a comprehensive research review. Int Orthop. 2018; 42(7):1747-1753.
[55] LIN CJ, LEE CC, SHIH YL, et al. Inhibition of mitochondria- and endoplasmic reticulum stress-mediated autophagy augments temozolomide-induced apoptosis in glioma cells. PLoS One. 2012;7(6): e38706.
[56] CYBULSKY AV. The intersecting roles of endoplasmic reticulum stress, ubiquitin- proteasome system, and autophagy in the pathogenesis of proteinuric kidney disease. Kidney Int. 2013;84(1):25-33.
[57] EL ZAOUI I, BEHAR-COHEN F, TORRIGLIA A. Glucocorticoids exert direct toxicity on microvasculature: analysis of cell death mechanisms. Toxicol Sci. 2015;143(2):441-453.
[58] YU QS, GUO WS, CHENG LM, et al. Glucocorticoids Significantly Influence the Transcriptome of Bone Microvascular Endothelial Cells of Human Femoral Head. Chin Med J (Engl). 2015;128(14):1956-1963.
[59] GAO Y, ZHU H, YANG F, et al. Glucocorticoid-activated IRE1α/XBP-1s signaling: an autophagy-associated protective pathway against endotheliocyte damage. Am J Physiol Cell Physiol. 2018;315(3): C300-C309.
[60] LIU W, ZHAO Z, NA Y, et al. Dexamethasone-induced production of reactive oxygen species promotes apoptosis via endoplasmic reticulum stress and autophagy in MC3T3-E1 cells. Int J Mol Med. 2018;41(4): 2028-2036.
[61] WEINSTEIN RS, NICHOLAS RW, MANOLAGAS SC. Apoptosis of osteocytes in glucocorticoid-induced osteonecrosis of the hip. J Clin Endocrinol Metab. 2000;85(8):2907-2912.
[62] BOYA P, COHEN I, ZAMZAMI N, et al. Endoplasmic reticulum stress-induced cell death requires mitochondrial membrane permeabilization. Cell Death Differ. 2002;9(4):465-467.
[63] ALMADA M, FONSECA BM, AMARAL C, et al. Anandamide oxidative metabolism-induced endoplasmic reticulum stress and apoptosis. Apoptosis. 2017;22(6):816-826.
[64] PLOTKIN LI, MANOLAGAS SC, BELLIDO T. Glucocorticoids induce osteocyte apoptosis by blocking focal adhesion kinase-mediated survival. Evidence for inside-out signaling leading to anoikis. J Biol Chem. 2007;282(33):24120-24130.
[65] TAO SC, YUAN T, RUI BY, et al. Exosomes derived from human platelet-rich plasma prevent apoptosis induced by glucocorticoid-associated endoplasmic reticulum stress in rat osteonecrosis of the femoral head via the Akt/Bad/Bcl-2 signal pathway. Theranostics. 2017;7(3):733-750.
[66] YANG J, WU Q, LV J, et al. 4-Phenyl butyric acid prevents glucocorticoid-induced osteoblast apoptosis by attenuating endoplasmic reticulum stress. J Bone Miner Metab. 2017;35(4):366-374.
[67] YIN J, HAN L, CONG W. Alpinumisoflavone rescues glucocorticoid-induced apoptosis of osteocytes via suppressing Nox2-dependent ROS generation. Pharmacol Rep. 2018;70(2):270-276.
[68] ZHANG M, LI S, PANG K, et al. Endoplasmic reticulum stress affected chondrocyte apoptosis in femoral head necrosis induced by glucocorticoid in broilers. Poult Sci. 2019;98(3):1111-1120.
[69] WEINSTEIN RS, CHEN JR, POWERS CC, et al. Promotion of osteoclast survival and antagonism of bisphosphonate-induced osteoclast apoptosis by glucocorticoids. J Clin Invest. 2002;109(8):1041-1048.
[70] WEI B, WEI W, ZHAO B, et al. Long non-coding RNA HOTAIR inhibits miR-17-5p to regulate osteogenic differentiation and proliferation in non-traumatic osteonecrosis of femoral head. PLoS One. 2017;12(2): e0169097.
[71] YU Z, FAN L, LI J, et al. Lithium prevents rat steroid-related osteonecrosis of the femoral head by β-catenin activation. Endocrine. 2016;52(2):380-390.
[72] LI J, FAN L, YU Z, et al. The effect of deferoxamine on angiogenesis and bone repair in steroid-induced osteonecrosis of rabbit femoral heads. Exp Biol Med (Maywood). 2015;240(2):273-280.
[73] BRANDI ML, COLLIN-OSDOBY P. Vascular biology and the skeleton. J Bone Miner Res. 2006;21(2):183-192.
[74] 高彦淳. 糖皮质激素引起的内质网应激与内皮细胞凋亡[D]. 上海:上海交通大学, 2018.
[75] 刘大全. 调节干细胞分化和内质网应激治疗股骨头坏死的机制研究[D]. 天津:天津医科大学, 2017.
[76] ZHANG Q, L V J, JIN L. Role of coagulopathy in glucocorticoid-induced osteonecrosis of the femoral head. J Int Med Res. 2018;46(6): 2141-2148.
[77] NARAYANAN A, KHANCHANDANI P, BORKAR RM, et al. Avascular Necrosis of Femoral Head: A Metabolomic, Biophysical, Biochemical, Electron Microscopic and Histopathological Characterization. Sci Rep. 2017;7(1):10721.
[78] KUBO T, UESHIMA K, SAITO M, et al. Clinical and basic research on steroid-induced osteonecrosis of the femoral head in Japan. J Orthop Sci. 2016;21(4):407-413.
[79] ADILI A, TROUSDALE RT. Femoral head resurfacing for the treatment of osteonecrosis in the young patient. Clin Orthop Relat Res. 2003;(417): 93-101.
[80] IURLARO R, MUÑOZ-PINEDO C. Cell death induced by endoplasmic reticulum stress. FEBS J. 2016;283(14):2640-2652.
[81] CUBILLOS-RUIZ JR, MOHAMED E, RODRIGUEZ PC. Unfolding anti-tumor immunity: ER stress responses sculpt tolerogenic myeloid cells in cancer. J Immunother Cancer. 2017;5:5. |