中国组织工程研究

中国组织工程研究 ›› 2015, Vol. 19 ›› Issue (9): 1335-1339.doi: 10.3969/j.issn.2095-4344.2015.09.004

• 人工假体 artificial prosthesis • 上一篇    下一篇

双侧全膝关节置换后下肢深静脉血栓形成与高血压的关系

王培丞，曹 力，杨德盛，胥伯勇，郭文涛，艾力•热黑   

  1. 新疆医科大学第一附属医院关节外科，新疆维吾尔族自治区乌鲁木齐市  830054
  • 修回日期:2014-12-29 出版日期:2015-02-26 发布日期:2015-02-26
  • 通讯作者: 曹力，主任医师，新疆医科大学第一附属医院关节外科，新疆维吾尔族自治区乌鲁木齐市 830054
  • 作者简介:王培丞，男，1988年生，四川省大竹县人，汉族，新疆医科大学第一附属医院在读硕士，主要从事骨与关节损伤研究。
  • 基金资助:

    卫生部优秀青年科技人才专项科研基金“临床新技术安全性与效果评价-关节置换安全性与效果评价”

Correlation between hypertension and deep venous thrombosis after bilateral total knee arthroplasty

Wang Pei-cheng, Cao Li, Yang De-sheng, Xu Bo-yong, Guo Wen-tao, Aili•Rehei   

  1. Department of Joint Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • Revised:2014-12-29 Online:2015-02-26 Published:2015-02-26
  • Contact: Cao Li, Chief physician, Department of Joint Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • About author:Wang Pei-cheng, Studying for master’s degree, Department of Joint Surgery, First Affiliated Hospital of Xinjiang Medical University, Urumqi 830054, Xinjiang Uygur Autonomous Region, China
  • Supported by:

    Program of Excellent Young Scientists of the Ministry of Health

PDF

506

被引次数

18

摘要：

背景：下肢深静脉血栓是人工全膝关节置换后的严重并发症之一，若不能及时妥当地诊断及处理会引起患者病情迁延不愈，甚至血栓脱落造成肺栓塞，危及患者生命。目前国内外研究并未确定有高血压病的患者行全膝关节置换后会增加下肢深静脉血栓的发生率。
目的：观察高血压是否会影响双侧人工全膝关节置换后患者下肢深静脉血栓的发生率。
方法：回顾性分析2010 年9月至2014年3月新疆医科大学第一附属医院关节外科因膝骨关节炎行双侧全膝关节置换患者的病历资料，根据患者是否合并有高血压，将其分为高血压组与对照组。在置换后通过彩色多普勒超声检查，诊断患者全膝关节置换后是否发生下肢深静脉血栓。比较两组间下肢深静脉血栓的发生率是否有差异，分析高血压与下肢深静脉血栓的关系。
结果与结论：共纳入525 例患者，高血压组219例，对照组306例。全膝关节置换后20例患者发生下肢深静脉血栓，发生率为3.8%，其中高血压组发生下肢深静脉血栓13例(2.5%)，对照组发生下肢深静脉血栓7例(1.3%)。通过卡方检验分析，高血压组全膝关节置换后发生下肢深静脉血栓的风险是对照组患者的2.7倍，差异有显著性意义(P < 0.05)。提示术前患有高血压病患者行全膝关节置换，其置换后下肢深静脉血栓发病率高于术前血压正常患者。


中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程


全文链接：

关键词: 植入物, 人工假体, 全膝关节置换, 高血压, 骨关节炎, 静脉血栓形成

Abstract:

BACKGROUND: Deep vein thrombosis is a serious complication of total knee arthroplasty surgery, if patients are not promptly diagnosed and treated properly, the healing of the patient’s condition may be delayed, and even blood clots shedding causes pulmonary embolism, endangering the lives of patients. At present, no evidence has supported that total knee arthroplasty can increase postoperative deep venous thrombosis incidence in hypertensive patients.
OBJECTIVE: To observe whether hypertension would influence the occurrence of deep venous thrombosis in patients who underwent total knee arthroplasty.
METHODS: A retrospective analysis was performed among patients underwent total knee arthroplasty in Department of Joint Surgery, the First Affiliated Hospital of Xinjiang Medical University from September 2010 to March 2014. Patients were divided into hypertension group and control group based on their medical history of hypertension. Doppler ultrasonography was applied to detect both lower extremities among these patients after operation, to diagnose if there was any evidence of deep venous thrombosis. The incidence of deep venous thrombosis in the two groups was compared. The correlation of hypertension and deep venous thrombosis was analyzed.
RESULTS AND CONCLUSION: A total of 525 patients were involved in this study, including 219 in hypertension group and 306 in control group. Among them, 20 patients appeared deep venous thrombosis and the incidence rate was 3.8%. 13 patients in the hypertension group (2.5%) and 7 patients in the control group (1.3%) developed deep venous thrombosis. Chi-square test showed that, the risk of deep venous thrombosis in the hypertension group was 2.7 times of that in the control group, and the differences were statistically significant between the two groups (P < 0.05). Hypertensive patients suffer a higher incidence rate of deep venous thrombosis after total knee arthroplasty compared with those with normal blood pressure.


中国组织工程研究杂志出版内容重点：人工关节；骨植入物；脊柱；骨折；内固定；数字化骨科；组织工程


全文链接：

Key words: Arthroplasty, Placement, Knee, Hypertension, Osteoarthritis, Vein thrombosis

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