中国组织工程研究

中国组织工程研究 ›› 2015, Vol. 19 ›› Issue (2): 196-200.doi: 10.3969/j.issn.2095-4344.2015.02.007

• 软骨组织构建 cartilage tissue construction • 上一篇    下一篇

骨桥与骨栓固定同种异体半月板移植的效果比较

彭亮权，朱伟民，王大平，陆  伟，冯文哲，陈  康   

  1. 深圳市第二人民医院运动医学科，广东省深圳市  518035
  • 收稿日期:2014-10-16 出版日期:2015-01-08 发布日期:2015-01-08
  • 通讯作者: 王大平，博士，教授，主任医师，博士生导师，深圳市第二人民医院运动医学科，广东省深圳市 518035
  • 作者简介:彭亮权，男，1979年生，广东省兴宁市人，2009年广州医科大学毕业，硕士，副主任医师，主要从事骨科运动医学研究。
  • 基金资助:

    深圳市科技计划项目(201302088)

Bone bridge and bone plug fixation methods for meniscal allograft transplantation

Peng Liang-quan, Zhu Wei-min, Wang Da-ping, Lu Wei, Feng Wen-zhe, Chen Kang   

  1. Department of Sport Medicine, Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
  • Received:2014-10-16 Online:2015-01-08 Published:2015-01-08
  • Contact: Wang Da-ping, M.D., Professor, Chief physician, Doctoral supervisor, Department of Sport Medicine, Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
  • About author:Peng Liang-quan, Master, Associate chief physician, Department of Sport Medicine, Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
  • Supported by:

    the Science and Technology Plan of Shenzhen City, No. 201302088

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摘要：

背景：文献报道，半月板移植骨桥及前后角骨栓固定较单纯软组织缝合固定效果更好，但关于骨桥与骨栓二者固定疗效比较的报道较少。
目的：对比分析骨桥与骨栓固定同种异体半月板移植的临床效果。
方法：18例外侧半月板切除后接受关节镜下同种异体外侧半月板移植患者，其中9例采用骨栓法、9例采用骨桥法行外侧半月板移植。随访采用症状询问，体征检查，目测类比疼痛评分、Lysholm和Tegner评分进行综合分析。所有患者平均每半年进行1次MRI 检查，观察膝关节半月板移植后形态状态及信号改变。
结果与结论：18例患者均进行了12-36个月的随访。所有患者随访时关节活动度均正常，均无明显的膝关节疼痛和肿胀，可以胜任日常活动和体育锻炼，无并发症出现。半月板移植后目测类比疼痛评分、Lysholm、Tegner评分均较移植前明显提高。MRI检查提示移植半月板移植后1年时替代存活很好。结果表明关节镜下的同种异体半月板移植安全可行，半月板移植可缓解半月板切除后出现的关节疼痛、肿胀等症状，骨桥固定与骨栓固定法临床疗效无明显差异。

 


中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程


全文链接：

关键词: 组织构建, 软骨组织工程, 半月板移植, 同种异体移植, 骨桥固定, 骨栓固定, 关节镜微创

Abstract:

BACKGROUND: Studies have reported that the bone bridge and bone plug for meniscal allograft transplantation show better outcomes than simple soft tissue suture, but there are rare studies concerning the comparison of their fixation effects.
OBJECTIVE: To compare the clinical effects of bone bridge and bone plug in meniscal allograft transplantation.
METHODS: Eighteen patients undergoing arthroscopy-assisted meniscal allograft transplantation were enrolled, including nine cases of bone plug fixation and nine cases of bone bridge fixation. Symptoms, physical examination, visual analog scale, Lysholm and Tegner scores were used to evaluate the clinic outcome. Every 6 months post operation, the signal and morphological changes of allograft meniscus was observed with MRI for each patient.
RESULTS AND CONCLUSION: All of the 18 patients were followed up for 12-36 months after transplantation. No complications, absence of knee pain and effusion, and disappearance of the discomfort within the meniscectomy compartments after prolonged activity during follow-up period were found in all patients. The patients were competent of daily life and sports activity. The visual analog scale, Lysholm and Tegner scores were significantly increased after transplantation. MRI showed that the vicariousness and livability of the allograft menisci appeared within 1 year post operation. The safety and feasibility of the arthroscopy-assisted meniscal allograft transplantation were approved. Knee pain, knee effusion and joint stability and function were improved after arthroscopic-assisted allograft meniscus transplantation, and there was no difference between the clinical curative effects of the two kinds of fixed methods.

 


中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程


全文链接：

Key words: Menisci, Tibial, Transplantation, Homologous, Arthroscopes

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