中国组织工程研究

中国组织工程研究 ›› 2018, Vol. 22 ›› Issue (17): 2722-2726.doi: 10.3969/j.issn.2095-4344.0534

• 干细胞移植 stem cell transplantation • 上一篇    下一篇

结构性脂肪颗粒移植6个月后面部脂肪容积的评价

赫 佳，赵 娴，韩雪松，代晓明，刘博言，张 莹，刘 流   

  1. 昆明医科大学第一附属医院整形外科，云南省昆明市 650031
  • 修回日期:2018-04-08 出版日期:2018-06-18 发布日期:2018-06-18
  • 通讯作者: 刘流，教授，博士生导师，昆明医科大学第一附属医院整形外科，云南省昆明市 650031
  • 作者简介:赫佳，男，1983年生，云南省昆明市人，2010年昆明医科大学毕业，硕士，助教，主要从事整形美容与修复重建方面的研究。
  • 基金资助:

    国家自然科学基金项目(81460246)

Assessing facial fat volume at 6 months after structural fat grafting

He Jia, Zhao Xian, Han Xue-song, Dai Xiao-ming, Liu Bo-yan, Zhang Ying, Liu Liu   

  1. Department of Plastic Surgery, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, China
  • Revised:2018-04-08 Online:2018-06-18 Published:2018-06-18
  • Contact: Liu Liu, Professor, Doctoral supervisor, Department of Plastic Surgery, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, China
  • About author:He Jia, Master, Assistant teacher, Department of Plastic Surgery, First Affiliated Hospital of Kunming Medical University, Kunming 650031, Yunnan Province, China
  • Supported by:

    the National Natural Science Foundation of China, No. 81460246

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被引次数

2

摘要：

文章快速阅读：

文题释义：
脂肪移植：是一种美容领域较新的一种治疗技术，选取脂肪量充足的部位作为供区，对供区及受区进行评估和标记后，对供区进行肿胀麻醉处理然后抽吸脂肪，处理获得的脂肪，将纯化后的脂肪颗粒移植至求美者受区，以提高受区脂肪容积，从而改善面部皱纹严重程度，提高求美者对术式的满意度，达到年轻化的效果。
自体结构性脂肪填充的优势：主要表现在创伤小、安全性高、见效快、并发症少、费用低等。脂肪中的干细胞对受区同样具有修复效果并提高脂肪细胞成活率，该方法可以起到双重修复作用，即填充修复及干细胞修复。而且对供区也具有一定的塑形效果，与传统的修复手段相比，这种移植方法为深层填充，并且是精准的在研究对象面部解剖结构内进行移植，患者手术后肿胀程度比较轻，更容易取得长期、稳定的效果。

 

摘要
背景：随着人们对美的追求越来越高，面部美容已被越来越多的人接受，随之出现了各种美容方法和术式，这些方法均需要高额的修复费用，并且造成的创伤也比较大，恢复很慢，而且还会引起永久性瘢痕，甚至出现瘢痕增生等情况。移植美容是一种较新的治疗方法，而移植物的选择对治疗效果具有重要的影响。
目的：探讨结构性脂肪颗粒移植在面部年轻化中的应用效果。
方法：选取自2016年5月至2017年5月间进行面部年轻化者21例作为研究对象，结合多方面因素对所有研究对象供区及受区进行评估。抽取供区脂肪，去除沉淀和油脂后植入供区。移植后6个月，通过调查问卷的形式对修复效果满意度、面部皱纹严重程度进行评分，统计再次补充注射例数及并发症发生例数，检测受区脂肪颗粒移植前后面部脂肪容积。
结果与结论：①移植后6个月随访显示仅2例研究对象要求接受再次脂肪颗粒移植；②通过1次或2次自体脂肪移植，所有研究对象面部容量不足、凹陷、静态纹均得到良好改善。所有研究对象对脂肪颗粒移植平均满意度评分为(8.47±0.43)分，移植后6个月面部脂肪容积较移植前有所增加(P < 0.05)，面部皱纹严重程度评分明显低于移植前(P < 0.05)；③仅有3例研究对象移植后6个月内出现并发症，其中感染、液化、脂肪栓塞各1例；④结果表明，采用结构性脂肪移植可以有效改善面部松弛、下垂等问题，具有良好的提升面部年轻化的效果。

中国组织工程研究杂志出版内容重点：干细胞；骨髓干细胞；造血干细胞；脂肪干细胞；肿瘤干细胞；胚胎干细胞；脐带脐血干细胞；干细胞诱导；干细胞分化；组织工程
ORCID: 0000-0002-2378-4990(赫佳)

关键词: 脂肪移植, 结构性, 面部年轻化, V-Line, 干细胞, 国家自然科学基金

Abstract:

BACKGROUND: With the increasing pursuit of beauty, facial cosmetics have become popular, and thereupon various cosmetic methods and surgical methods have emerged. However, high costs, large trauma, slow recovery, permanent scars and even scar hypertrophy can result from these cosmetic surgeries. Transplantation is a relatively new method for facial cosmetics, and the choice of graft is crucial for cosmetic effects.
OBJECTIVE: To evaluate the curative effect of facial rejuvenation surgery with structural fat grafting.
METHODS: From May 2016 to May 2017, 21 cases of facial rejuvenation were selected. All subjects were assessed for donor sites and affected areas by combining various factors. Fat tissues were isolated from the donor site, and implanted into the affected area after sediment and grease removal. Patient satisfaction and the severity of facial wrinkles were scored through a survey questionnaire. At 6 months after transplantation, the number of request to replenish injections and number of complication cases were statistically recorded. The volume of facial fat tissues in the affected area was calculated before and after transplantation.
RESULTS AND CONCLUSION: Two subjects required re-transplantation during the 6-month postoperative follow-up. Facial capacity, depression, and static patterns of all subjects were well improved after one or two autologous fat transplantations. The average satisfaction score on fat transplantation for all the subjects was 8.47±0.43. The volume of facial fat tissues at 6 months after transplantation was significantly increased compared with that before operation (P < 0.05). The postoperative severity of facial wrinkles was significantly lower than before operation (P < 0.05). Only three subjects had complications within 6 months after transplantation, including one case of infection, one of liquefaction and one of fat embolism. V-Line liquid lift with structural fat grafting can effectively improve facial relaxation, sagging and other issues, with a good upgrade of facial rejuvenation effect. 

中国组织工程研究杂志出版内容重点：干细胞；骨髓干细胞；造血干细胞；脂肪干细胞；肿瘤干细胞；胚胎干细胞；脐带脐血干细胞；干细胞诱导；干细胞分化；组织工程

Key words: Adipose Tissue, Transplantation, Face, Tissue Engineering

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