中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (20): 3630-3633.doi: 10.3969/j.issn.1673-8225.2012.20.005

• 骨髓干细胞 bone marrow stem cells • 上一篇    下一篇

应力负荷下兔肩袖急性断裂重建后腱-骨修复过程中的超声检测*☆

李  森1，靳安民2，张  辉2，闵少雄2，王  清1   

  1. 1泸州医学院附属医院脊柱外科，四川省泸州市  646000；2南方医科大学附属珠江医院骨科中心，广东省广州市 510282
  • 收稿日期:2011-10-17 修回日期:2011-11-02 出版日期:2012-05-13 发布日期:2012-05-13
  • 通讯作者: 王清，硕士，主任医师，泸州医学院附属医院脊柱外科，四川省泸州市 646000 wqspine2004@163.com
  • 作者简介:王清，硕士，主任医师，泸州医学院附属医院脊柱外科，四川省泸州市 646000 wqspine2004@163.com
  • 基金资助:

    李森☆，男，1979年生，河南省西华县人，汉族，2010年南方医科大学毕业，博士，主治医师，主要从事脊柱、脊髓损伤及骨关节损伤方面研究。jht187@163.com

Ultrasonic testing of tendon-bone repair in rabbits with postreconstructive acute ruptured rotator cuff under stress

Li Sen1, Jin An-min2, Zhang Hui2, Min Shao-xiong2, Wang Qing1   

  1. 1Department of Spine Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou  646000, Sichuan Province, China; 2Department of Orthopedic Center, Affiliated Zhujiang Hospital of Southern Medical University, Guangzhou  510282, Guangdong Province, China
  • Received:2011-10-17 Revised:2011-11-02 Online:2012-05-13 Published:2012-05-13
  • Contact: Wang Qing, Master, Chief physician, Department of Spine Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China wqspine2004@163.com
  • About author:Li Sen☆, Doctor, Attending physician, Department of Spine Surgery, Affiliated Hospital of Luzhou Medical College, Luzhou 646000, Sichuan Province, China jht187@163.com
  • Supported by:

     the Natural Science Foundation of Luzhou Medical College, No. 2010108-64*

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摘要：

背景：已有研究证明，应力刺激对肩袖腱-骨损伤后的修复起到促进作用，但超声动态检测其修复过程的相关研究还较少。
目的：应用超声检测应力刺激促进兔肩袖急性断裂重建后腱-骨修复的过程。
方法：选取成年雄性新西兰白兔，建立应力负荷下兔肩袖急性断裂重建后腱-骨修复动物模型，随机分为2组：应力负荷组与非应力负荷组。应力负荷组术后第2周应用兔肩关节被动活动控制装置进行训练；非应力负荷组正常笼养。
结果与结论：术后2周，关节超声检查显示两组冈上肌腱止点处回声仍连续性中断，应力负荷组炎性渗出物信号较明显。术后4周，两组冈上肌腱止点重建处均出现线性连续回声，应力负荷组稍显明显。术后6周，两组冈上肌腱腱-骨之间回声仍不连续，应力负荷组腱性连续性中断回声带明显减小。术后8周，两组冈上肌腱腱-骨之间回声仍不完全连续，腱-骨结构连接组织回声区较前宽大。结果显示一定的应力刺激在兔肩袖急性断裂术后腱-骨修复过程中起到积极促进作用，且超声可以相对无创、准确地显示兔肩袖腱-骨修复的动态过程。

关键词: 应力负荷, 重建术后, 腱-骨修复, 超声, 兔

Abstract:

BACKGROUND: Pervious studies have showed stress can promote tendon-bone repair, but studies related to ultrasonic testing during tendon-bone repair are few.
OBJECTIVE: To study the changes in ultrasonic testing of tendon-bone in rabbits with postreconstructive acute ruptured rotator cuff under stress.
METHODS: Adult male New Zealand white rabbits were selected for establishing animal models of tendon-bone repair with postreconstructive acute ruptured rotator cuff under stress, and then were randomly divided into two groups: stress group and non-stress group. Rabbits in the stress group were trained at 2 weeks after operation. Non-stress group was with caging and free.
RESULTS AND CONCLUSION: At 2 weeks after operation, the echoes at the site of the rabbit supraspinatus tendon-bone were still discontinuous and the signals of inflammatory exudation appeared more evidently than before in the two groups. At 4 weeks after operation, the linear continuous echoes appeared at the site of the rabbit supraspinatus tendon-bone in two groups, which showed more obvious in the stress group than that in the non-stress group. At 6 weeks after operation, the echoes at the site of the rabbit supraspinatus tendon-bone were still discontinuous in two groups, the areas of discontinuous echoes in stress group tendon significantly reduced. At 8 weeks after operation, the echoes at the site of the rabbit supraspinatus tendon-bone were still discontinuous in two groups, the areas of echoes of the tissues combined tendon and bone is more spacious than before. A certain degree of stress stimulation plays an active role in the repairing of postoperative actue ruptured rabbit rotator cuff tendon-bone and ultrasonic testing can detect the dynamic role of tendon-bone repair with non-invasive and accurate.

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