中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (3): 527-527.doi: 10.3969/j.issn.1673-8225.2012.03.033

• 生物材料综述 biomaterial review • 上一篇    下一篇

纳米氧化锌抗菌性能及机制*★◆

胡占江1，赵  忠1，王雪梅2   

  1. 1兰州大学物理科学与技术学院，磁学与磁性材料教育部重点实验室，甘肃省兰州市  730000；2兰州大学口腔医学院，甘肃省兰州市  730000
  • 收稿日期:2011-05-13 修回日期:2011-07-30 出版日期:2012-01-15 发布日期:2012-01-15
  • 通讯作者: 王雪梅，讲师，兰州大学口腔医学院，甘肃省兰州市 730000 w_xuemei@ hotmail.com
  • 作者简介:胡占江★，男，1984年生，河北省邯郸市人，满族，2010年邯郸学院毕业，硕士，主要从事表面物理化学的研究。 huzj2010@ lzu.edu.cn
  • 基金资助:

    甘肃省自然科学基金项目(1010RJZA112)。

Antibacterial properties and mechanism of nano-zinc oxide

Hu Zhan-jiang1, Zhao Zhong1, Wang Xue-mei2   

  1. 1Key Laboratory for Magnetism and Magnetic Materials of the Ministry of Education, School of Physical Science and Technology, Lanzhou University, Lanzhou  730000, Gansu Province, China; 2School of Stomatology, Lanzhou University, Lanzhou  730000, Gansu Province, China
  • Received:2011-05-13 Revised:2011-07-30 Online:2012-01-15 Published:2012-01-15
  • Contact: Wang Xue-mei, Lecturer, School of Stomatology, Lanzhou University, Lanzhou 730000, Gansu Province, China w_xuemei@ hotmail.com
  • About author:Hu Zhan-jiang★, Master, Key Laboratory for Magnetism and Magnetic Materials of the Ministry of Education, School of Physical Science and Technology, Lanzhou University, Lanzhou 730000, Gansu Province, China huzj2010@ lzu.edu.cn
  • Supported by:

    Natural Science Foundation of Gansu Province, No. 1010RJZA112*

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摘要：

 

背景：氧化锌作为一种活性氧化物类抗菌材料，拥有良好的生物相容性、安全性以及长效性。
目的：总结纳米氧化锌的抗菌性能及其抗菌机制。
方法：应用计算机检索1995-12/2011-02 Elsevier (ScienceDirect)及Web of Science期刊引文索引数据库相关文章，检索词为“antibacterial properties of nano-zinc oxide”，并限定文章语言种类为English。同时计算机检索1995-12/2011-02 CNKI学术总库及万方数据库相关文章，检索词为“纳米氧化锌抗菌性能”，并限定文章语言种类为中文。共检索到文献75篇。
结果与结论：纳米氧化锌在很多方面的杀菌性能都很强，并且由于其良好的生物相容性、安全性以及长效性，可以取代医学上其他活性氧化物抗菌材料。文章从纳米氧化锌抗菌性能改性，以及形貌与结构对抗菌性的影响等方面，详细总结了纳米氧化锌的抗菌性能及其抗菌机制，但是如何提高纳米氧化锌的利用率和杀菌性能，如何使纳米氧化锌应用于更多细菌的抑制或更广阔的领域，都需要人们的继续努力。
关键词：纳米氧化锌；抗菌材料；抗菌机制；生物材料；综述文献
doi:10.3969/j.issn.1673-8225.2012.03.033

 

关键词: 纳米氧化锌, 抗菌材料, 抗菌机制, 生物材料, 综述文献

Abstract:

BACKGROUND: The zinc oxide has a good biocompatibility, security and long effectiveness, and can be used as a type of antibacterial material of active oxide category.
OBJECTIVE: To summarize the antibacterial properties and mechanism of nano-zinc oxide (nano-ZnO).
METHODS: A computer-based online search of related papers from December 1995 to February 2011 was performed in Elsevier (Science Direct) and Web of Science databases using the key words of “antibacterial properties of nano-ZnO” in English, and in CNKI and Wanfang databases using the key words of “antibacterial properties of nano-ZnO” in Chinese. Totally 75 literatures were selected.
RESULTS AND CONCLUSION: The nano-ZnO has a strong bactericidal property in many fields. It can replace other materials of active oxide category based on its good biocompatibility, security and long effectiveness. The antibacterial properties and mechanism of nano-ZnO were summarized in this study from the sides of modified antibacterial properties and the effects of morphology and structure of nano-ZnO on antibacterial properties. However, more studies are in need to solve how to improve the utilization and antibacterial properties, and to expand the applications of nano-ZnO in antibacterial and other fields.
    

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