中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (42): 7907-7910.doi: 10.3969/j.issn.1673-8225.2011.42.028

• 生物材料综述 biomaterial review • 上一篇    下一篇

可降解医用膜预防硬膜外粘连的研究概况

杨冬松，张绍昆，闫  明，刘理迪   

  1. 吉林大学第一医院脊柱外科，吉林省长春市   130021
  • 收稿日期:2011-04-19 修回日期:2011-05-14 出版日期:2011-10-15 发布日期:2011-10-15
  • 通讯作者: 张绍昆，副教授，硕士生导师,主要从事脊柱外科及组织工程研究。 drzhangsk@yahoo.com.cn
  • 作者简介:杨冬松★，男, 1982年生,河南省驻马店市人,汉族，吉林大学在读硕士，医师，主要从事脊柱外科的研究。 dsyang1982@163.com

Degradable medical films for prevention of epidural adhesion

Yang Dong-song, Zhang Shao-kun, Yan Ming, Liu Li-di   

  1. Spine Center, First Affiliated Hospital, Jilin University, Changchun  130021, Jilin Province, China
  • Received:2011-04-19 Revised:2011-05-14 Online:2011-10-15 Published:2011-10-15
  • Contact: Zhang Shao-kun, Associate professor, Master’s supervisor, Spine Center, First Affiliated Hospital, Jilin University, Changchun 130021, Jilin Province, China drzhangsk@ yahoo.com.cn
  • About author:Yang Dong-song★, Studying for master’s degree, Physician, Spine Center, First Affiliated Hospital, Jilin University, Changchun 130021, Jilin Province, China dsyang1982@163.com

PDF

418

被引次数

6

摘要：

背景：预防硬膜外粘连的方法很多，而可降解医用膜因为其独特的性质，在未来有着良好的应用前景。
目的：概括、总结可降解医用膜的优缺点及实验应用效果。
方法：应用计算机检索2001-01/2011-01 PubMed数据库、中国知网数据库相关文章，中文检索词为“椎板切除术，可降解医用膜，硬膜粘连”，英文检索词为“Laminectomy，degradable medical films，epidural adhesion”。排除重复文献，筛选纳入28篇文献进行综述。
结果及结论：可降解医用膜能很好的预防硬膜外粘连，并且其降解产物可被人体吸收或通过呼吸及体液排出体外，故不会对人体产生危害，可作为预防硬膜外粘连的理想的材料。可降解医用膜众多，实验结果也不尽相同，由于单一种医用膜都各自存在缺点，将两种或两种以上膜进行改性后可克服各自身的缺点，是未来研究的方向。

关键词: 可降解医用膜, 硬膜外粘连, 椎板切除术, 生物材料, 综述文献

Abstract:

BACKGROUND: There are many methods for preventing epidural adhesion. Because of the unique properties, gradable medical films have a good application prospect in the future.
OBJECTIVE: To summarize the advantages, disadvantages and clinical effects of biodegradable medical films.
METHODS: A computer-based online search was performed on PuMed and CNKI databases with key words “Laminectomy, degradable medical films, epidural adhesion” in English and Chinese from January 2001 to January 2011. Repeated literatures were eliminated, and 28 articles were included.
RESULTS AND CONCLUSION: Biodegradable medical films can prevent epidural adhesion effectively, and their products can be absorbed by human body or discharged with breath and body fluids, which cannot cause harm to human body. Therefore, these films can be the ideal materials for preventing epidural adhesion. The biodegradable medical films are numerous, and experimental results are also different. Because shortcomings of a single kind of medical film, the modified film with two or more films can overcome the shortcomings, and there is a broad prospect in clinical trials in the future.

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