中国组织工程研究

中国组织工程研究 ›› 2024, Vol. 28 ›› Issue (32): 5110-5115.doi: 10.12307/2024.500

• 组织工程相关大数据分析 Big data analysis in tissue engineering • 上一篇    下一篇

高精度经颅直流电刺激研究热点的可视化分析

闫  杰1，2，周  静2，赵敬璞2，张清芳1，2，周明超2，王玉龙2   

  1. 1山东中医药大学，山东省济南市  250355；2深圳市第二人民医院，广东省深圳市  518035
  • 收稿日期:2023-08-24 接受日期:2023-10-12 出版日期:2024-11-18 发布日期:2023-12-28
  • 通讯作者: 王玉龙，教授，主任医师，深圳市第二人民医院，广东省深圳市 518035
  • 作者简介:闫杰，男，1998年生，山西省临汾市人，汉族，山东中医药大学在读硕士，主要从事神经调控技术、脑卒中及意识障碍方面的研究。
  • 基金资助:
    深圳市三名工程“南京医科大学励建安团队”资助项目(SZSM202111010)，项目负责人：王玉龙；深圳市科技计划项目(JCYJ20220530151018039)，项目负责人：赵敬璞

Visual analysis of high-definition transcranial direct current stimulation research

Yan Jie1, 2, Zhou Jing2, Zhao Jingpu2, Zhang Qingfang1, 2, Zhou Mingchao2, Wang Yulong2   

  1. 1Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China; 2Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
  • Received:2023-08-24 Accepted:2023-10-12 Online:2024-11-18 Published:2023-12-28
  • Contact: Wang Yulong, Professor, Chief physician, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China; Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
  • About author:Yan Jie, Master candidate, Shandong University of Traditional Chinese Medicine, Jinan 250355, Shandong Province, China; Shenzhen Second People’s Hospital, Shenzhen 518035, Guangdong Province, China
  • Supported by:
    Sanming Project of Medicine in Shenzhen, No. SZSM202111010 (to WYL); Shenzhen Science and Technology Plan Project, No. JCYJ20220530151018039 (to ZJP)

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摘要：


文题释义：

高精度经颅直流电刺激：使用多个小面积电极组合，将直流电集中作用于特定脑区，通过恒定、聚焦、低强度的电流精准调控大脑皮质，从而引起大脑皮质兴奋性的改变。
可视化分析：借助图谱等视觉化手段，将复杂的文献信息呈现出来，以便更直观地理解和分析数据间的相互关系。


背景：近年来，高精度经颅直流电刺激因其非侵入性调控大脑功能的潜在益处而备受关注，但目前仍未有研究对其进行可视化分析。

目的：对高精度经颅直流电刺激相关研究进行可视化分析，探索研究现状及热点趋势。 
方法：从Web of Science(WOS)核心合集数据库中检索2010-01-01/2023-05-06发表的与高精度经颅直流电刺激相关的英文文献，应用VOSviewer软件对纳入文献的来源期刊、国家/地区、作者、机构、被引文献和关键词进行可视化分析并绘制知识图谱，探索该领域的研究现状及热点。 

结果与结论：①共纳入336篇文献，高精度经颅直流电刺激的发文量逐年增加。其中，美国的发文量最多(141篇)，被引次数为4 221，中国发文量仅次于美国(70篇)，被引次数为401。②《Brain Stimulation》是发文量最多的期刊(28篇)，Marom Bikson是发文量最多的作者(37篇)，纽约市立大学城市学院是发文量最多的机构(35篇)。③运动皮质、调控、工作记忆、兴奋性及背外侧前额叶是该领域出现频次排名前5的关键词。近5年的热点关键词主要包括注意力缺陷/多动症、脑网络及刺激强度等。④目前，高精度经颅直流电刺激领域的研究文献数量相对较少，但总体呈现上升趋势，这反映出该领域具备较大的研究潜力。预计该领域的研究将持续聚焦于高精度经颅直流电刺激在认知精神类疾病的应用，并基于脑网络进一步揭示其作用于运动皮质及背外侧前额叶等靶点的治疗机制。

https://orcid.org/0009-0005-8860-4734(闫杰)；https://orcid.org/0000-0002-0947-6967(王玉龙)

中国组织工程研究杂志出版内容重点：组织构建；骨细胞；软骨细胞；细胞培养；成纤维细胞；血管内皮细胞；骨质疏松；组织工程

关键词: 高精度经颅直流电刺激, 文献计量学, 可视化分析, 研究现状, 热点趋势

Abstract: BACKGROUND: In recent years, High-definition transcranial direct current stimulation (HD-tDCS) has garnered significant attention due to its potential non-invasive modulation of brain function. However, there is still a lack of visual analysis in the literature regarding this technique.
OBJECTIVE: To perform a visual analysis of HD-tDCS-related research so as to explore the current status and trends in this field.
METHODS: English literature related to HD-tDCS was retrieved from the Web of Science Core Collection database covering the period from January 1, 2010 to May 6, 2023. The VOSviewer software was used to visualize and analyze the source journals, countries/regions, authors, institutions, cited references, and keywords of the included literature, creating a knowledge map to uncover the research landscape and hotspots.
RESULTS AND CONCLUSION: A total of 336 articles were included, showing a consistent increase in the annual publication count of HD-tDCS research. Among these, the United States contributed the highest number of publications (141 articles) with 4 221 citations, followed by China with 70 articles and 401 citations. Brain Stimulation was the most prolific journal (28 articles), Marom Bikson was the most productive author (37 articles), and The City College of New York was the most active institution (35 articles). The most frequently mentioned keywords in the field included motor cortex, regulation, working memory, excitability, and dorsolateral prefrontal cortex. Notable recent keywords in the last 5 years include attention-deficit/hyperactivity disorder, brain networks, and stimulation intensity. Currently, the volume of HD-tDCS research is relatively limited, but is on an upward trajectory, indicating substantial research potential. It is expected that future studies in this domain will continue to focus on the application of HD-tDCS in cognitive and neuropsychiatric disorders, while also exploring its therapeutic mechanisms targeting the motor cortex and dorsolateral prefrontal cortex based on brain network analysis.

Key words: high-definition transcranial direct current stimulation, bibliometrics, visual analysis, research status, current trends

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