[1] Havranek O,Spacek M,Hubacek P,et al.No association between the TP53, codon 72 polymorphism and risk or prognosis of Hodgkin and non-Hodgkin lymphoma. Leuk Res.2011;35(8):1117-1179.[2] Nagpal N,Ahmad HM,Molparia B,et al.MicroRNA-191, an estrogen-responsive microRNA, functions as an oncogenic regulator in human breast cancer. Carcinogenesis. 2013; 34(8):1889-1899.[3] Chow A,Lucas D,Hidalgo A,et al.Bone marrow CD169+ macrophages promote the retention of hematopoietic stem and progenitor cells in the mesenchymal stem cell niche.J Exp Med.2011;(208):261-271.[4] Dickhut A,Schwerdtfeger RL,Ritter M,et al.Mesenchymal stem cells obtained after bone marrow transplantation or peripheral blood stem cell transplantation originate from host tissue.Ann Hematol.2005;84(11):722-727.[5] Anthony BA.Regulation of hematopoietic stem cells by bone marrow stromal cells.Trends Immunol.2014;35(1):32-37.[6] Shi C,Lv T,Xiang Z,et al.Role of Wnt/β-catenin signaling in epithelial differentiation of lung resident mesenchymal stem cells.Journal of Cellular Biochemistry, 2014;116(8):1532-1539.[7] Nicolay NH,Liang Y,Lopez Perez R,et al.Mesenchymal stem cells are resistant to carbon ion radiotherapy. Oncotarget. 2015;6(4):2076-2087.[8] Nicolay NH,Sommer E,Perez RL,et al.Mesenchymal stem cells are sensitive to treatment with kinase inhibitors and ionizing radiation.Strahlenther Onkol. 2014;190(11): 1037-1045.[9] NNicolay NH,Lopez Perez R,Saffrich R,et al.Radio-resistant mesenchymal stem cells-mechanisms of resistance and potential implications for the clinic.Oncotarget. 2015;6(23): 19366-19380.[10] Shao L,Sun Y,Zhang Z,et al.Deletion of proapoptotic Puma selectively protects hematopoietic stem and progenitor cells against high-dose radiation.Blood.2010;15(23): 4707-4714.[11] WangJ,SunQ,MoritaY,etal.A differentiation checkpoint limits hematopoietic stem cell self-renewal in response to DNA damage.Cell.2012;148(5):1001-1014.[12] Luo Y,Li L,Zou P,et al.Rapamycin enhances long-term hematopoietic reconstitution of ex vivo expanded mouse hematopoietic stem cells by inhibiting senescence. Transplantation.2014;97(11):20-29.[13] Li H,Wang Y,Pazhanisamy SK,et al.Mn(III) meso-tetrakis-( N -ethylpyridinium-2-yl) porphyrin mitigates total body irradiation-induced long-term bone marrow suppression.Free Rad Biol Med.2011;51(1):30-37.[14] Porto ML,Rodrigues BP,Menezes TN,et al.Reactive oxygen species contribute to dysfunction of bone marrow hematopoietic stem cells in aged C57BL/6 J mice.J Biomed Sci.2015;22(1):1-13.[15] Gómez Puerto MC, Verhagen LP, Braat AK, et al. Activation of autophagy by FOXO3 regulates redox homeostasis during osteogenic differentiation. Autophagy. 2016 ;12(10): 1804-1816.[16] Wang L,Xiao H,Xing Z,et al.The role of telomeres and telomerase in hematologic malignancies and hematopoietic stem cell transplantation.J Hematol Oncol.2014;7(1):1-10.[17] Shao L,Luo Y,Zhou D.Hematopoietic stem cell injury induced by ionizing radiation.Antioxid Redox Signal. 2014;20(9): 1447-1462.[18] Greca ML,Grasso G,Antonelli G,et al.Neoadjuvant therapy for locally advanced melanoma: new strategies with targeted therapies.Onco Targets Ther.2013;7(2):1115-1121.[19] Chun SH, Park GY, Han YK, et al.Effect of low dose radiation on differentiation of bone marrow cells into dendritic cells. Dose Response. 2012 ;11(3):374-384.[20] Diazmuñoz MD,Bell SE,Fairfax K,et al.The RNA-binding protein HuR is essential for the B cell antibody response.Nat Immunol.2015;16(4):415-425.[21] Sadi B,Li C,Ko R,et al.A study on the effect of the internal exposure to 210Po on the excretion of urinary proteins in rats.Radiat Environ Biophys. 2016;55(2):161-169 .[22] Blank CU.The perspective of immunotherapy: new molecules and new mechanisms of action in immune modulation.Curr Opin Oncol.2014;26(2):204-214.[23] Imamura M,Shigematsu A.Allogeneic hematopoietic stem cell transplantation in adult acute lymphoblastic leukemia: potential benefit of medium-dose etoposide conditioning. ExpHematol Oncol. 2015;4(1):1-15.[24] Modiano JF,Lindborg BA,Mcelmurry RT,et al.Mesenchymal stromal cells inhibit murine syngeneic anti-tumor immune responses by attenuating inflammation and reorganizing the tumor microenvironment.Cancer Immunol Immunother. 2015;64(11):1449-1460.[25] Ishida T,Ishida M,Tashiro S,et al.Role of DNA damage in cardiovascular disease.Circ J.2014;78(1):42-50.[26] Pasi F,Paolini A,Nano R,et al.Effects of single or combined treatments with radiation and chemotherapy on survival and danger signals expression in glioblastoma cell lines.Biomed Res Int.2014;2014(3):1327-1338.[27] Schweizer MT,Drake CG.Immunotherapy for prostate cancer: recent developments and future challenges.Cancer Metastasis Rev. 2014 ;33(2-3):641-655.[28] Nicolay NH,Liang Y,Lopez PR,et al.Mesenchymal stem cells are resistant to carbon ion radiotherapy. Oncotarget. 2014; 6(4):2076-2087.[29] Fekete N,Erle A,Amann EM,et al.Effect of high-dose irradiation on human bone-marrow-derived mesenchymal stromal cells.Tissue Eng Part C Methods.2015;21(2): 112-122.[30] Wright LE,Buijs JT,Kim H,et al.Single-Limb Irradiation Induces Local and Systemic Bone Loss in a Murine Mode.J Bone Miner Res. 2015;30(7):1268-1279.[31] Nicolay NH,Perez RL,Rühle A,et al.Mesenchymal stem cells maintain their defining stem cell characteristics after treatment with cisplatin.Sci Rep.2016;6:20035. [32] Molaei S,Roudkenar MH,Amiri F,et al.Down-regulation of the autophagy gene, ATG7, protects bone marrow-derived mesenchymal stem cells from stressful conditions. Blood Res. 2015;50(2):80-86.[33] Wu J,Niu J,Li X,et al. Hypoxia induces autophagy of bone marrow-derived mesenchymal stem cells via activation of ERK1/2. Cellular Physiology & Biochemistry International J Exp Cell PhysiolBiochem Pharmacol.2014;33(5):1467-1474.[34] Khodadi E,Shahrabi S,Shahjahani M,et al.Role of stem cell factor in the placental niche.Cell Tissue Res.2016; 366(3): 523-531.[35] Hu KX,Sun QY,Guo M,et al.The radiation protection and therapy effects of mesenchymal stem cells in mice with acute radiation injury.Br J Radiol.2010;83(985):52-58.[36] Psaltis PJ,Zannettino A CW,Worthley SG,et al.Concise Review: Mesenchymal Stromal Cells: Potential for Cardiovascular Repair.Stem Cells.2008;26(9):2201-2210.[37] Aronin CEP,Tuan RS.Therapeutic potential of the immunomodulatory activities of adult mesenchymal stem cells.Birth Defects Res C Embryo Today.2010;90(1):67-74.[38] He N,Zhang L,Cui J,et al.Bone marrow vascular niche: home for hematopoietic stem cells.BoneMarrow Res.2014; 2014(1-2):128436-128436.[39] Zhang YJ,Yang YX,Hu MY,et al.Importance of CD44 on umbilical cord mesenchymal stem cells for expansion of hematopoietic cells.Cellular and molecular biology (Noisy-le-Grand, France).2015;61(2):18-25. [40] Uccelli A,Moretta L,Pistoia V.Mesenchymal stem cells in health and disease.Nat Rev Immunol.2008;8(9):726-736.[41] Walenda T,Bokermann G,Ventura Ferreira MS,et al. Synergistic effects of growth factors and mesenchymal stromal cells for expansion of hematopoietic stem and progenitor cells.ExpHematol.2011;39(6):617-628.[42] Fajardo-Orduña GR,Mayani H,Montesinos JJ.Hematopoietic Support Capacity of Mesenchymal Stem Cells: Biology and Clinical Potential.Arch MedRes.2015; 46(8):589-596.[43] Zhang C,Chen XH,Zhang X,et al.Human umbilical cord blood-derived stromal cells: a new resource in hematopoietic reconstitution in mouse haploidentical transplantation. Transplant Proc.2010;42(9):3739-3744.[44] De Toni F,Poglio S,Youcef AB,et al.Human adipose-derived stromal cells efficiently support hematopoiesis in vitro and in vivo: a key step for therapeutic studies. Stem Cells Dev.2011; 20(12):2127-2138[45] Raicevic G,Najar M,Stamatopoulos B,et al.The source of human mesenchymal stromal cells influences their TLR profile as well as their functional properties.Cell Immunol. 2011;270(2):207-216. [46] Wolfgang Wagner M.D. Ph.D, Roderburg C, Wein F, et al. Molecular and Secretory Profiles of Human Mesenchymal Stromal Cells and Their Abilities to Maintain Primitive Hematopoietic Progenitors.Stem Cells.2007;25(10): 2638-2647.[47] Beyth S,Borovsky Z,Mevorach D,et al.Human mesenchymal stem cells alter antigen-presenting cell maturation and induce T-cell unresponsiveness.Blood.2005;105(5):2214-2219.[48] Wen S,Dooner M,Cheng Y,et al.Mesenchymal stromal cell derived extracellular vesicles rescue radiation damage to murine marrow hematopoietic cells.Leukemia. 2016;30(11): 2221-2231.[49] Blanco B,Herrero-Sánchez MC,Rodríguez-Serrano C,et al.Immunomodulatory effects of bone marrow versus adipose tissue derived mesenchymal stromal cells on NK cells: implications in the transplantation setting.Eur J Haematol. 2016;97(6):528-537. [50] Maccario R,Podestà M,Moretta A,et al.Interaction of human mesenchymal stem cells with cells involved in alloantigen-specific immune response favors the differentiation of CD4+ T-cell subsets expressing a regulatory/suppressive phenotype.Haematologica. 2005; 90(4):516-525.[51] Li H,Guo ZK,Jiang XX,et al.Mesenchymal Stem Cells Alter Migratory Property of T and Dendritic Cells to Delay the Development of Murine Lethal Acute Graft-Versus-Host Disease.Stem Cells.2008;26(10):2531-2541.[52] Aggarwal S,Pittenger MF.Human mesenchymal stem cells modulate allogeneic immune cell responses. Blood.2005; 105(4):1815-1822.[53] Klyushnenkova E,Mosca JD,Zernetkina V,et al.T cell responses to allogeneic human mesenchymal stem cells: immunogenicity, tolerance, and suppression.J Biomed Sci. 2005;12(1):47-57.[54] Hou DL,Chen L, Liu B,et al.Identification of common gene networks responsive to radiotherapy in human cancer cells. Cancer Gene Ther.2014;32(21):542-548.[55] Worku M,Fersht N,Martindale C,et al.Sequential transformation of mesenchymal stem cells is associated with increased radiosensitivity and reduced DNA repair capacity. Radiat Res.2013;179(6):698-706.[56] Al-Nbaheen M, ishnubalaji R,Ali D,et al.Human stromal (mesenchymal) stem cells from bone marrow, adipose tissue and skin exhibit differences in molecular phenotype and differentiation potential.Stem Cell Rev.2013;9(1):32-43. |