关键词: 血管内支架成形术, 脑供血动脉狭窄, 缺血性脑卒中, 并发症, 生物材料

Abstract:

OBJECTIVE: To summarize the application of endovascular stent-assisted angioplasty material in the treatment of cerebral artery stenosis.
METHODS: An online search of VIP database from January 2000 to October 2010 was performed for articles about endovascular stent implantation in the treatment of cerebral artery stenosis. Key words are endovascular stent-assisted angioplasty; cerebral artery stenosis; ischemic stroke; complications. Inclusion criteria: endovascular stent treatment for cerebral artery stenosis. Exclusion criteria: repeated studies or older literature.
RESULTS: Metal stents have achieved remarkable results in clinical therapy, but it may cause thrombosis, induce permanent retention in vivo and high restenosis, is difficult to attach drugs onto the metal surface and other shortcomings. In recent years the scaffold material, configuration design and production process have been greatly improved, especially the emergence of membrane stent and the concept of biological scaffold raised in the late 1980s and early 1990s have proposed a new stage of endovascular stent.
CONCLUSION: With the development of endovascular stent techniques, the endovascular stent under cerebral protection device has become the main treatment for intracranial and extracranial artery stenosis, the stent safety and effectiveness have been significantly improved, but there are still problems such as thrombosis, cerebral hemorrhage, restenosis and excessive perfusion.