[1] Imai S, Tokunaga Y, Maeda T, et al. Calcitonin gene-related peptide, substance P, and tyrosine hydroxylase- immunoreactive innervation of rat bone marrows: an immunohistochemical and ultrastructural investigation on possible efferent and afferent mechanisms.J Orthop Res. 1997;15(1):133-140.
[2] Hohn A, Leibrock J, Bailey K, et al. Identification and characterization of a novel member of the nerve growth factor/brain-derived neurotrophic factor family. Nature. 1990; 344(6264):339-341.
[3] Lu B, Pang PT, Woo NH. The yin and yang of neurotrophin action. Nat Rev Neurosci. 2005;6(8):603-614.
[4] Reichardt LF.Neurotrophin-regulated signalling pathways. Philos Trans R Soc Lond B Biol Sci.2006;361(1473): 1545-1564.
[5] Matsuda H, Coughlin MD, Bienenstock J, et al. Nerve growth factor promotes human hemopoietic colony growth and differentiation. Proc Natl Acad Sci U S A. 1988;85(17): 6508-6512.
[6] Mitsiadis TA, Luukko K. Neurotrophins in odontogenesis. Int J Dev Biol.1995;39(1):195-202.
[7] Barde YA, Edgar D, Thoenen H.Purification of a new neurotrophic factor from mammalian brain. EMBO J. 1982; 1(5): 549-553.
[8] Leibrock J, Lottspeich F, Hohn A, et al. Molecular cloning and expression of brain-derived neurotrophic factor. Nature. 1989; 341(6238):149-152.
[9] Seidah NG, Benjannet S, Pareek S, et al. Cellular processing of the neurotrophin precursors of NT3 and BDNF by the mammalian proprotein convertases. FEBS Lett.1996;379(3): 247-250.
[10] Lee R, Kermani P, Teng KK, et al.Regulation of cell survival by secreted proneurotrophins. Science. 2001;294(5548): 1945-1948.
[11] Radziejewski C, Robinson RC, DiStefano PS, et al. Dimeric structure and conformational stability of brain-derived neurotrophic factor and neurotrophin-3. Biochemistry. 1992; 31(18):4431-4436.
[12] Teng HK, Teng KK, Lee R, et al.ProBDNF induces neuronal apoptosis via activation of a receptor complex of p75NTR and sortilin. J Neurosci. 200525(22):5455-5563.
[13] Woo NH, Teng HK, Siao CJ, et al.Activation of p75NTR by proBDNF facilitates hippocampal long-term depression. Peptides. Nat Neurosci. 2005;8(8):1069-1077.
[14] Kang H, Welcher AA, Shelton D,et al.Neurotrophins and time: different roles for TrkB signaling in hippocampal long-term potentiation. Neuron.1997;19(3):653-64.
[15] Windisch JM, Marksteiner R, Lang ME, et al.Brain-derived neurotrophic factor, neurotrophin-3, and neurotrophin-4 bind to a single leucine-rich motif of TrkB. Biochemistry.1995; 34(35):11256-11263.
[16] Ultsch MH1, Wiesmann C, Simmons LC, et al. Crystal structures of the neurotrophin-binding domain of TrkA, TrkB and TrkC. J Mol Biol. 1999;290(1):149-159.
[17] Boeshore KL,Luckey CN,Zigmond RE,et al.TrkB isoforms with distinct neurotrophin specificities are expressed in predominantly nonoverlapping populations of avian dorsal root ganglion neurons. J Neurosci. 1999;19(12):4739-4747.
[18] Obermeier A, Bradshaw RA, Seedorf K, et al. Neuronal differentiation signals are controlled by nerve growth factor receptor/Trk binding sites for SHC and PLC gamma. EMBO J. 1994;13(7):1585-1590.
[19] Vetter ML, Martin-Zanca D, Parada LF, et al. Nerve growth factor rapidly stimulates tyrosine phosphorylation of phospholipase C-gamma 1 by a kinase activity associated with the product of the trk protooncogene.Proc Natl Acad Sci U S A. 1991;88(13):5650-5654.
[20] Roux PP, Barker PA. Neurotrophin signaling through the p75 neurotrophin receptor.Prog Neurobiol.2002;67(3):203-233.
[21] Yamamoto N, Akamatsu H, Hasegawa S, et al. Isolation of multipotent stem cells from mouse adipose tissue.J Dermatol Sci. 2007;48(1):43-52.
[22] Mikami Y, Ishii Y, Watanabe N, et al. CD271/p75(NTR) inhibits the differentiation of mesenchymal stem cells into osteogenic, adipogenic, chondrogenic, and myogenic lineages. Stem Cells Dev. 2011;20(5):901-913.
[23] Baldwin AN, Shooter EM. Zone mapping of the binding domain of the rat low affinity nerve growth factor receptor by the introduction of novel N-glycosylation sites.J Biol Chem. 1995;270(9):4594-4602.
[24] Chapman BS.A region of the 75 kDa neurotrophin receptor homologous to the death domains of TNFR-I and Fas.FEBS Lett. 1995;374(2):216-220.
[25] Aloyz RS, Bamji SX, Pozniak CD, et al. p53 is essential for developmental neuron death as regulated by the TrkA and p75 neurotrophin receptors.J Cell Biol.1998;143(6):1691-1703.
[26] Bibel M, Hoppe E, Barde YA. Biochemical and functional interactions between the neurotrophin receptors trk and p75NTR.EMBO J. 1999;18(3):616-622.
[27] Makkerh JP, Ceni C, Auld DS, et al. p75 neurotrophin receptor reduces ligand-induced Trk receptor ubiquitination and delays Trk receptor internalization and degradation.EMBO Rep. 2005;6(10):936-941.
[28] Yamashiro T, Fukunaga T, Yamashita K, et al. Gene and protein expression of brain-derived neurotrophic factor and TrkB in bone and cartilage.Bone. 2001;28(4):404-409.
[29] Hutchison MR. BDNF alters ERK/p38 MAPK activity ratios to promote differentiation in growth plate chondrocytes.Bone. Mol Endocrinol. 2012;26(8):1406-1416.
[30] Hutchison MR. Mice with a conditional deletion of the neurotrophin receptor TrkB are dwarfed, and are similar to mice with a MAPK14 deletion.PLoS One. 2013;8(6):e66206.
[31] Alexander D, Schäfer F, Munz A, et al.LNGFR induction during osteogenesis of human jaw periosteum-derived cells.Cell Physiol Biochem. 2009;24(3-4):283-290.
[32] Mikami Y, Suzuki S, Ishii Y, et al. The p75 neurotrophin receptor regulates MC3T3-E1 osteoblastic differentiation. Differentiation. 2012;84(5):392-399.
[33] Akiyama Y, Mikami Y, Watanabe E, et al.The P75 neurotrophin receptor regulates proliferation of the human MG63 osteoblast cell line.Differentiation. 2014;87(3-4):111-118.
[34] Asaumi K, Nakanishi T, Asahara H, et al. Expression of neurotrophins and their receptors (TRK) during fracture healing. Bone. 2000;26(6):625-633.
[35] Kilian O, Hartmann S, Dongowski N, et al. Expression of neurotrophins and their receptors (TRK) during fracture healing. Bone. 2000;26(6):625-633.
[36] 龙雄武.脑外伤合并骨折时脑源性神经营养因子对骨折愈合的影响[D].中南大学.外科学(骨科) , 2010.
[37] Aiga A, Asaumi K, Lee YJ, et al. Expression of neurotrophins and their receptors tropomyosin-related kinases (Trk) under tension-stress during distraction osteogenesis.Acta Med Okayama. 2006;60(5):267-277.
[38] Camerino C, Zayzafoon M, Rymaszewski M, et al. Central depletion of brain-derived neurotrophic factor in mice results in high bone mass and metabolic phenotype.Endocrinology. 2012;153(11):5394-5405.
[39] Deng FY, Tan LJ, Shen H, et al. SNP rs6265 regulates protein phosphorylation and osteoblast differentiation and influences BMD in humans.J Bone Miner Res. 2013;28(12):2498-2507.
[40] Roodman GD.Pathogenesis of myeloma bone disease. J Cell Biochem. 2010 Feb 1;109(2):283-291.
[41] 王雅丹,胡豫,魏文宁,等.脑源性神经营养因子在多发性骨髓瘤患者血浆中的表达[J].临床血液学杂志,2004,17(2):82-83,86.
[42] 孙春艳,胡豫,吴涛,等.脑源性神经营养因子及其受体在多发性骨髓瘤细胞中的表达及意义[J].中华内科杂志,2005,44(12):906-909.
[43] Ai LS, Sun CY, Wang YD, et al. Gene silencing of the BDNF/TrkB axis in multiple myeloma blocks bone destruction and tumor burden in vitro and in vivo.Int J Cancer. 2013; 133(5):1074-1084.
[44] Simonet WS, Lacey DL, Dunstan CR, et al. Osteoprotegerin: a novel secreted protein involved in the regulation of bone density.Cell. 1997 Apr 18;89(2):309-319.
[45] Sun CY, Hu Y, Huang J, et al. Brain-derived neurotrophic factor induces proliferation, migration, and VEGF secretion in human multiple myeloma cells via activation of MEK-ERK and PI3K/AKT signaling.Tumour Biol. 2010;31(2):121-128.
[46] 王雅丹,胡豫,黄靖,等.抗脑源性神经营养因子单克隆抗体在骨髓瘤异体移植动物模型中的抗肿瘤效应[J]. 中国实验血液学杂志. 2008;16(5):1069-1072.
[47] Mizuno N, Shiba H, Xu WP, et al. Effect of neurotrophins on differentiation, calcification and proliferation in cultures of human pulp cells.Cell Biol Int. 2007;31(12):1462-9.
[48] 王晓东,王捍国,倪龙兴.脑源性神经营养因子在人牙髓干细胞中的表达及其对细胞增殖分化的影响[J].牙体牙髓牙周病学杂志. 2009;19(5):247-250.
[49] Kajiya M, Shiba H, Fujita T, et al. Brain-derived neurotrophic factor stimulates bone/cementum-related protein gene expression in cementoblasts.J Biol Chem. 2008;283(23): 16259-16267.
[50] Kurihara H, Shinohara H, Yoshino H, et al. Neurotrophins in cultured cells from periodontal tissues.J Periodontol. 2003; 74(1):76-84.
[51] Takeda K, Shiba H, Mizuno N, et al. Brain-derived neurotrophic factor enhances periodontal tissue regeneration. Tissue Eng. 2005;11(9-10):1618-1629.
[52] Jimbo R, Tovar N, Janal MN, et al. The effect of brain-derived neurotrophic factor on periodontal furcation defects.PLoS One. 2014;9(1):e84845.
[53] Takeda K, Sakai N, Shiba H, et al. Characteristics of high-molecular-weight hyaluronic acid as a brain-derived neurotrophic factor scaffold in periodontal tissue regeneration.Tissue Eng Part A. 2011;17(7-8):955-967. |