中国组织工程研究 ›› 2018, Vol. 22 ›› Issue (30): 4841-4848.doi: 10.3969/j.issn.2095-4344.0965

• 生物材料综述 biomaterial review • 上一篇    下一篇

聚乳酸全降解血管支架的专利技术

杨金辉,于 群,赵 洁   

  1. 国家知识产权局专利局,材料工程发明审查部,北京市 100088
  • 收稿日期:2018-03-02 出版日期:2018-10-28 发布日期:2018-10-28
  • 通讯作者: 杨金辉,国家知识产权局专利局,材料工程发明审查部,北京市 100088
  • 作者简介:杨金辉,男,1981年生,安徽省固镇县人,汉族,2003年北京化工大学毕业,主任科员,主要从事医用材料领域发明专利审查。

An overview of patented technology for fully-degradable polylactic acid stents

Yang Jin-hui, Yu Qun, Zhao Jie   

  1. Examining Division for Materials Engineering Inventions, State Intellectual Property Office of China, Beijing 100088, China
  • Received:2018-03-02 Online:2018-10-28 Published:2018-10-28
  • Contact: Yang Jin-hui, Examining Division for Materials Engineering Inventions, State Intellectual Property Office of China, Beijing 100088, China
  • About author:Yang Jin-hui, Examining Division for Materials Engineering Inventions, State Intellectual Property Office of China, Beijing 100088, China

摘要:

文章快速阅读:

 

文题释义:
聚乳酸全降解血管支架:使用聚合物材料制作的全降解血管支架本身可负载抗增生药物,并且一定时间后可以在体内能够完全降解,避免引起血栓,也不会对之后的其他治疗产生阻碍。使用聚乳酸材料的全降解血管支架是其中的研发焦点。
 
 
背景:专利分析有助于了解相关领域专利技术的发展脉络和关键技术,提高对该领域技术发展的把握能力。
目的:探讨聚乳酸全降解血管支架领域专利申请态势及技术发展路线。
方法:检索聚乳酸全降解血管支架领域全球专利申请,从申请量年度趋势、主要申请人分布、专利技术分支、重要申请人分析等方面对专利技术进行分析,重点分析共混改性聚乳酸血管支架主体材料核心专利、专利技术发展演进。

结果与结论:聚乳酸全降解血管支架是目前血管支架领域的重点研究方向。材料、工艺方法和结构设计是该领域专利的主要申请方向,其中以对材料的研究改进申请量最多,也是该领域起步最早的技术分支。在技术需求方面,提高支架材料的力学性能、控制支架降解速率、改善药物控释性能是主要的关注热点。

ORCID: 0000-0003-4480-9023(杨金辉)

关键词: 血管支架, 全降解, 聚乳酸, 专利, 技术发展, 生物材料

Abstract:

BACKGROUND: Research on patented technology contributes to understanding the development and key technology of the related field, and enhances the ability to grasp the technological developments in this field.

OBJECTIVE: To investigate the patent application situation and technical development route in the field of fully-degradable polylactic acid stents.
METHODS: We searched the patent applications for fully-degradable polylactic acid stents all over the world, and analyzed relevant information in the following aspects: annual application quantity, the distribution of the main applicants, the branches of the patent technology, the analysis of the important applicants. Afterwards, we focused on the blending modification of polylactic acid stents, and analyzed its core patents and the development of patented technology.

RESULTS AND CONCLUSION: The fully-degradable polylactic acid stent is the focus direction of current research in the field of vascular stents. Materials, technique and structural design are the main aspects for patent applications in this field. Among them, the application for improvement of materials is the most frequently conducted, which is the earliest branch of technology in this field. In terms of technical requirements, improving the mechanical properties of scaffolds, controlling the degradation rate of stents, and improving the controlled release of drugs are the main concerns.

中国组织工程研究杂志出版内容重点:生物材料;骨生物材料; 口腔生物材料; 纳米材料; 缓释材料; 材料相容性;组织工程

Key words: Patents, Tissue Engineering

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