中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (35): 6475-6478.doi: 10.3969/j.issn.1673-8225.2011.35.004

• 骨与关节损伤基础实验 basic experiments of bone and joint injury • 上一篇    下一篇

捆绑带束缚压力对骨折模型动物骨痂形成及愈合的影响

李立军，倪东馗，郑道明，庞小建   

  1. 天津医科大学第二医院骨科，天津市  300211
  • 收稿日期:2011-03-30 修回日期:2011-06-09 出版日期:2011-08-27 发布日期:2011-08-27
  • 通讯作者: 倪东馗，硕士，主任医师，天津医科大学第二医院骨科，天津市 300211 ndkui@sina.com
  • 作者简介:李立军★，男，1977年生，天津市人，汉族，天津医科大学在读硕士，主治医师，主要从事创伤骨科研究。 lilijun6208@sohu.com
  • 基金资助:

    天津市卫生局科研课题项目(07KI38)。

Effect of bound stress due to Cerclage band on callus formation and fracture healing in animal models

Li Li-jun, Ni Dong-kui, Zheng Dao-ming, Pang Xiao-jian   

  1. Department of Orthopedics, the Second Hospital, Tianjin Medical University, Tianjin  300211, China
  • Received:2011-03-30 Revised:2011-06-09 Online:2011-08-27 Published:2011-08-27
  • Contact: Ni Dong-kui, Master, Chief physician, Department of Orthopedics, the Second Hospital, Tianjin Medical University, Tianjin 300211, China
  • About author:Li Li-jun★, Studying for master’s degree, Attending physician, Department of Orthopedics, the Second Hospital, Tianjin Medical University, Tianjin 300211, China lilijun6208@sohu.com
  • Supported by:

    Science and Technology Research Plan of Tianjin Health Bureau, No. 07KI38*

PDF

352

被引次数

4

摘要：

背景：有些观点认为捆绑带的使用会影响骨折部位的血运甚至造成骨折延迟愈合与骨折不愈合。
目的：观察3种不同束缚压力捆绑带对骨折动物模型骨痂形成及愈合的影响。
方法：建立新西兰大白兔股骨干非负重骨折动物模型，髓内固定后随机分为3组，分别在骨折部位加用200，150，100 N束缚压力的捆绑带固定，术后2，4，6周观察骨痂形成及愈合。
结果与结论：200 N压力组骨折固定牢固，但骨折断端外骨痂形成受限，无骨愈合，影响断端远期稳定性。100 N压力组早期骨折断端不稳定，虽不影响骨折愈合，但容易出现畸形愈合。150 N压力组压力适中，骨折固定与愈合均良好。提示在保持适当束缚压力的情况下，捆绑带可以有效维持骨折部位稳定，避免骨折移位或畸形愈合，保障骨折正常愈合，对骨折部位骨膜血运无异常影响，有助于促进骨折早期愈合。

关键词: 捆绑带, 骨折, 骨折愈合, 骨痂, 组织构建实验造模

Abstract:

BACKGROUND: Some people believe that Cerclage band can influence the blood supply at fracture site leading to delayed healing and nonunion of fractures.
OBJECTIVE: To observe the effects of Cerclage band with three different bound stresses on the callus formation and fracture healing in fracture animal models.
METHODS: Femoral shaft fracture animal models of non-weight-bearing were established and divided into three groups. The cerclage band with three different bound stresses (200, 150, 100 N) was added at the fracture site, separately. Callus formation and fracture healing were observed at 2, 4, 6 weeks postoperatively.
RESULTS AND CONCLUSION: In the 200 N group, the callus formation at the fracture site was limited, no bone healed and the long-term stability of the fracture end was impacted. In the 100 N group, there was no influence on fracture healing, but deformity healing was easly found. In the 150 N group, the fractures fixed and healed well. In circumstances of maintaining the appropriate bound stress, the cerclage bands added at the fracture site can effectively maintain the stability and can avoid fracture displacement or deformity healing, so as to protect the normal fracture healing, and the blood supply of periosteum in the fracture site cannot be affected. The healing progress can be accelerated.

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