中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (3): 529-532.doi: 10.3969/j.issn.1673-8225.2010.03.036

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

生物补片在盆底修补和重建中的应用

肖  帆   

  1. 井冈山大学医学院，江西省吉安市 343000
  • 出版日期:2010-01-15 发布日期:2010-01-15
  • 作者简介:肖 帆★，女，1971年生，江西省吉水县人，汉族，1997年南昌大学医学院毕业，硕士，副教授，副主任医师，主要从事妇产科临床、教学与科研。 xiaofan92059@163.com

Application of biological patch in pelvic restoration and reconstruction

Xiao Fan   

  1. Medical College of Jinggangshan University, Ji’an   343000, Jiangxi Province, China
  • Online:2010-01-15 Published:2010-01-15
  • About author:Xiao Fan★, Master, Associate professor, Associate chief physician, Medical College of Jinggangshan University, Ji’an 343000, Jiangxi Province, China xiaofan92059@163.com

PDF

529

被引次数

18

摘要：

背景：熟悉补片的分类、特性，以及宿主与补片之间的反应，对于修复外科手术材料的合理选择是十分必要的。
目的：对补片及修复材料的分类、性质及其在盆底修补和重建中的应用和并发症的处理进行归纳总结。
方法：应用计算机检索PubMed数据库（http://www.ncbi.nlm.nih.gov/PubMed）及CNKI数据库（www.cnki.net/index.htm），在标题和摘要中以“补片材料，聚丙烯，复合补片”或“reconstructive pelvic surgery，repair，replacement”为检索词进行检索。选择文章内容与补片类型、材料学特点、生物相容性及其应用效果相关，同一领域文献则选择近期发表或发表在权威杂志文章。根据纳入标准选择24篇文献用于进行综述。
结果和结论：聚丙烯补片的优点是编织的网，网孔较大，有利于纤维组织长入，提高了组织的强度和抗拉性，白细胞和巨噬细胞可自由进入网孔内，因此不易藏匿细菌，故具较好的抗感染能力，感染后多可不去除网片。而膨化聚四氟乙烯层则质地柔软、表面光滑，组织耐受性非常好，可防止与腹腔内组织粘连，而其亚微米水平的孔径防止了细菌的侵入，它所造成的炎症及异物反应是目前人工合成材料中最轻的。

关键词: 补片材料, 聚丙烯, 聚四氟乙烯, 复合补片, 综述文献

Abstract:

BACKGROUND: Understanding of patch classification, characteristics, and reaction with host is necessary for best selection of reparative surgery materials.
OBJECTIVE: To summarize the patch classification, characteristics and its application in pelvic reconstruction, as well as the complications.
METHODS: A computer-based online search of PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and CNKI database (www.cnki.net/index.htm) was performed for related articles with the key words “patch, polypropylene, compound patch” in Chinese and “reconstructive pelvic surgery, repair, replacement” in English. Articles regarding patch classification, characteristics, biocompatibility, and application effect, or in the same circle published recently in authoritative journals were included. A total of 24 articles were finally selected.   
RESULTS AND CONCLUSION: Polypropylene patch is weaved network, with large mesh, which allows for fiber tissue ingrowth and improves tissue intensity and tensile strength. Leukocyte and macrophage can enter the mesh, so the patch has good anti-infection ability. Expanded polytetrafluoroethylene is soft and smooth, with good tissue tolerance, and can prevent affixion with intraabdominal tissues. Moreover, the submicron pore diameter prevents bacteria invasion. The inflammation and foreign body reaction induced by the expanded polytetrafluoroethylene is the most slight among artificial synthetic materials.

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