中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (12): 2209-2212.doi: 10.3969/j.issn.1673-8225.2011.12.029

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

创伤性腹壁缺损修补材料的生物相容性及其应用

方  骏   

  1. 安徽医科大学第一附属医院干部外科，安徽省合肥市 230022
  • 收稿日期:2011-01-25 修回日期:2011-02-25 出版日期:2011-03-19 发布日期:2011-03-19
  • 作者简介:方骏，男，1975年生，安徽省安庆市人，汉族，1999年华中科技大学同济医学院毕业，主治医师，主要从事普外科胃肠肿瘤、胆道方面疾病研究。 9191119@163.com

Application and biocompatibility of traumatic abdominal wall defect repair materials

Fang Jun   

  1. The Firt Affiliated Hospital of Anhui Medical University, Hefei  230022, Anhui Province, China
  • Received:2011-01-25 Revised:2011-02-25 Online:2011-03-19 Published:2011-03-19
  • About author:Fang Jun, Attending physician, the Firt Affiliated Hospital of Anhui Medical University, Hefei 230022, Anhui Province, China 9191119@163.com

PDF

586

被引次数

10

摘要：

背景：近年来修复腹壁缺损的方法有了改进与创新，生物材料的应用使腹壁缺损的修复效果有所改观，明显降低了各种腹壁疝的复发和巨大缺损修复后腹壁疝的发生。
目的：评价不同腹壁缺损修补材料临床应用的效果及修补后与宿主的生物相容性。
方法：以 “腹壁缺损，修补，聚丙烯补片，硅胶膜，黏膜，移植，相容性”为中文关键词，“abnormal wall defect; repair; polypropylene patch, silica gel, mucous membrane, transplant, compatibility”为英文关键词，采用计算机检索2005-01/ 2010-10相关文章。纳入与创伤性腹壁修复材料学相关及不同修补材料在腹壁缺损中应用的文章。
结果与结论：目前临床上用于修复腹壁缺损的材料比较多，曾经尝试过多种腹壁修复材料，主要有以下两类：生物性材料包括自体组织(如阔筋膜、肌皮瓣、自体真皮等)、同种异体组织(如羊膜、硬脑膜等)、异种异体组织(如猪心包膜、膈肌、牛腹膜等)。非生物性材料包括金属网织物(如银、铂合金、不锈钢等)、高分子化合物(如Malex，Teflon，Dacron等)。膨体聚四氟乙烯是目前应用较多的腹壁修补材料，但其抗感染能力较差，一旦感染往往需要移去补片。因此寻找优良的生物、植物材料或自体、异体复合材料势在必行。

关键词: 腹壁缺损, 修补, 聚丙烯补片, 硅胶膜, 黏膜, 移植, 生物相容性

Abstract:

BACKGROUND: Abdominal wall defect repair method in recent years has been improved and innovated. The application of biomaterials makes abdominal wall defect repair improved to some extent, and significantly reduces the recurrence of various lateral ventral syndromes and the occurrence of lateral ventral syndrome after large defect repair.
OBJECTIVE: To evaluate the clinical effect of different repairing materials of abdominal wall defect and biocompatibility of the host after repairing abdominal wall defect.
METHODS: Taking “abdominal wall defect, repair, polypropylene patch, silica gel, mucous membrane, transplant, compatibility” in Chinese and English as search terms to retrieve the correlated articles between January 2005 and October 2010. The articles about traumatic abdominal wall repairing materials and the application of different repairing materials in the abdominal wall defect were included.
RESULTS AND CONCLUSION: At present, the materials used to repairing abdominal wall defect are more in clinic. A variety of abdominal wall repair materials had been tried. Mainly in the following categories: biological materials, including autologous tissue (fascia, muscle flap, autologous dermis), allograft tissue (amnion, cerebral dura mater), heterogeneous allograft tissue (pig pericardium, diaphragm, cow peritoneum); non-biological materials, including metal mesh fabric (silver, platinum alloys, stainless steel), high molecular compound (malex, teflon, dacron). Expanded polytetrafiuoroethylene is is used more often in the abdominal wall repair material, but its anti-infections ability is poor. Once infected often need to remove the patch. Therefore, finding good biological, plant material or autologous, allogeneic composite materials is imperative.

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