[1] BENJAMIN EJ, VIRANI SS, CALLAWAY CW, et al. Heart Disease and Stroke Statistics-2018 Update: A Report From the American Heart Association. Circulation. 2018;137(12):e67-e492.
[2] KIM JS. tPA Helpers in the Treatment of Acute Ischemic Stroke: Are They Ready for Clinical Use? J Stroke. 2019;21(2):160-174.
[3] BOSHUIZEN MCS, STEINBERG GK. Stem Cell-Based Immunomodulation After Stroke: Effects on Brain Repair Processes. Stroke. 2018;49(6): 1563-1570.
[4] JENDELOVA P, KUBINOVA S, SANDVIG I, et al. Current developments in cell- and biomaterial-based approaches for stroke repair. Expert Opin Biol Ther. 2016;16(1):43-56.
[5] DIRNAGL U, IADECOLA C, MOSKOWITZ MA. Pathobiology of ischaemic stroke: an integrated view. Trends Neurosci. 1999;22(9):391-397.
[6] LI P, STETLER RA, LEAK RK, et al. Oxidative stress and DNA damage after cerebral ischemia: Potential therapeutic targets to repair the genome and improve stroke recovery. Neuropharmacology. 2018;134(Pt B): 208-217.
[7] PATEL AR, RITZEL R, MCCULLOUGH LD, et al. Microglia and ischemic stroke: a double-edged sword. Int J Physiol Pathophysiol Pharmacol. 2013;5(2):73-90.
[8] HALL JB, DOBROVOLSKAIA MA, PATRI AK, et al. Characterization of nanoparticles for therapeutics. Nanomedicine (Lond). 2007;2(6):789-803.
[9] AMREDDY N, BABU A, MURALIDHARAN R, et al. Recent Advances in Nanoparticle-Based Cancer Drug and Gene Delivery. Adv Cancer Res. 2018;137:115-170.
[10] SHAO K, SINGHA S, CLEMENTE-CASARES X, et al. Nanoparticle-Based Immunotherapy for Cancer. ACS Nano. 2014;9(1):16-30.
[11] SANGTANI A, NAG OK, FIELD LD, et al. Multifunctional nanoparticle composites: progress in the use of soft and hard nanoparticles for drug delivery and imaging. Wiley Interdiscip Rev Nanomed Nanobiotechnol. 2017;9(6):e1466.
[12] TSOU YH, ZHANG XQ, ZHU H, et al. Drug Delivery to the Brain across the Blood-Brain Barrier Using Nanomaterials. Small. 2017;13(43):1701921.
[13] BHARADWAJ VN, NGUYEN DT, KODIBAGKAR VD, et al. Nanoparticle-Based Therapeutics for Brain Injury. Adv Healthc Mater. 2018;7(1): 10.1002/adhm.201700668.
[14] GONZALEZ-NIETO D, FERNANDEZ-SERRA R, PEREZ-RIGUEIRO J, et al. Biomaterials to Neuroprotect the Stroke Brain: A Large Opportunity for Narrow Time Windows. Cells. 2020;9(5):1074.
[15] YUAN ZY, HU YL, GAO JQ. Brain Localization and Neurotoxicity Evaluation of Polysorbate 80-Modified Chitosan Nanoparticles in Rats. PLoS One. 2015;10(8):e0134722.
[16] SO PW, EKONOMOU A, GALLEY K, et al. Intraperitoneal delivery of acetate-encapsulated liposomal nanoparticles for neuroprotection of the penumbra in a rat model of ischemic stroke. Int J Nanomed. 2019;14:1979-1991.
[17] GAO Y, CHEN X, LIU H. A facile approach for synthesis of nano-CeO2 particles loaded co-polymer matrix and their colossal role for blood-brain barrier permeability in Cerebral Ischemia. J Photochem Photobiol B. 2018;187:184-189.
[18] ZHAI L, MAIMAITIMING Z, CAO X, et al. Nitrogen-doped carbon nanocages and human umbilical cord mesenchymal stem cells cooperatively inhibit neuroinflammation and protect against ischemic stroke. Neurosci Lett. 2019;708:134346.
[19] CHOI HS, LIU W, MISRA P, et al. Renal clearance of quantum dots. Nat Biotechnol. 2007;25(10):1165-1170.
[20] JO DH, KIM JH, LEE TG, et al. Size, surface charge, and shape determine therapeutic effects of nanoparticles on brain and retinal diseases. Nanomedicine. 2015;11(7):1603-1611.
[21] MASSERINI M. Nanoparticles for Brain Drug Delivery. ISRN Biochemistry. 2013;2013:1-18.
[22] ZHOU Y, PENG Z, SEVEN ES, et al. Crossing the blood-brain barrier with nanoparticles. J Control Release. 2018;270:290-303.
[23] DONG X. Current Strategies for Brain Drug Delivery. Theranostics. 2018; 8(6):1481-1493.
[24] NAM J, WON N, BANG J, et al. Surface engineering of inorganic nanoparticles for imaging and therapy. Adv Drug Deliv Rev. 2013; 65(5):622-648.
[25] ERNSTING MJ, MURAKAMI M, ROY A, et al. Factors controlling the pharmacokinetics, biodistribution and intratumoral penetration of nanoparticles. J Control Release. 2013;172(3):782-794.
[26] KOLHAR P, ANSELMO AC, GUPTA V, et al. Using shape effects to target antibody-coated nanoparticles to lung and brain endothelium. Proc Natl Acad Sci U S A. 2013;110(26):10753-10758.
[27] SARAIVA C, PRACA C, FERREIRA R, et al. Nanoparticle-mediated brain drug delivery: Overcoming blood-brain barrier to treat neurodegenerative diseases. J Control Release. 2016;235:34-47.
[28] YANG X, XU L, ZHOU J, et al. Integration of phospholipid-complex nanocarrier assembly with endogenous N-oleoylethanolamine for efficient stroke therapy. J Nanobiotechnol. 2019;17(1):8.
[29] AHMAD N, UMAR S, ASHAFAQ M, et al. A comparative study of PNIPAM nanoparticles of curcumin, demethoxycurcumin, and bisdemethoxycurcumin and their effects on oxidative stress markers in experimental stroke. Protoplasma. 2013;250(6):1327-1338.
[30] FURTADO D, BJORNMALM M, AYTON S, et al. Overcoming the Blood-Brain Barrier: The Role of Nanomaterials in Treating Neurological Diseases. Adv Mater. 2018;30(46):e1801362.
[31] HUANG S, HUANG Z, FU Z, et al. A Novel Drug Delivery Carrier Comprised of Nimodipine Drug Solution and a Nanoemulsion: Preparation, Characterization, in vitro, and in vivo Studies. Int J Nanomedicine. 2020;15:1161-1172.
[32] YOUSEFI-MANESH H, RASHIDIAN A, HEMMATI S, et al. Therapeutic effects of modafinil in ischemic stroke; possible role of NF-κB downregulation. Immunopharmacol Immunotoxicol. 2019;41(5):558-564.
[33] KAKKAR V, MUPPU SK, CHOPRA K, et al. Curcumin loaded solid lipid nanoparticles: an efficient formulation approach for cerebral ischemic reperfusion injury in rats. Eur J Pharm Biopharm. 2013;85(3 Pt A): 339-345.
[34] PARTOAZAR A, NASOOHI S, REZAYAT SM, et al. Nanoliposome containing cyclosporine A reduced neuroinflammation responses and improved neurological activities in cerebral ischemia/reperfusion in rat. Fund Clin Pharmacol. 2017;31(2):185-193.
[35] MA J, ZHANG S, LIU J, et al. Targeted Drug Delivery to Stroke via Chemotactic Recruitment of Nanoparticles Coated with Membrane of Engineered Neural Stem Cells. Small. 2019;15(35):e1902011.
[36] NAGAI N, YOSHIOKA C, ITO Y, et al. Intravenous Administration of Cilostazol Nanoparticles Ameliorates Acute Ischemic Stroke in a Cerebral Ischemia/Reperfusion-Induced Injury Model. Int J Mol Sci. 2015;16(12):29329-29344.
[37] VERMA SK, ARORA I, JAVED K, et al. Enhancement in the Neuroprotective Power of Riluzole Against Cerebral Ischemia Using a Brain Targeted Drug Delivery Vehicle. ACS Appl Mater Interfaces. 2016; 8(30):19716-19723.
[38] ZHAO LX, LIU AC, YU SW, et al. The permeability of puerarin loaded poly(butylcyanoacrylate) nanoparticles coated with polysorbate 80 on the blood-brain barrier and its protective effect against cerebral ischemia/reperfusion injury. Biol Pharm Bull. 2013;36(8):1263-1270.
[39] YEMISCI M, CABAN S, GURSOY-OZDEMIR Y, et al. Systemically Administered Brain-Targeted Nanoparticles Transport Peptides across the Blood—Brain Barrier and Provide Neuroprotection. J Cerebr Blood F Met. 2015;35(3):469-475.
[40] BAO Q, HU P, XU Y, et al. Simultaneous Blood–Brain Barrier Crossing and Protection for Stroke Treatment Based on Edaravone-Loaded Ceria Nanoparticles. ACS Nano. 2018;12(7):6794-6805.
[41] ZHANG C, LING CL, PANG L, et al. Direct Macromolecular Drug Delivery to Cerebral Ischemia Area using Neutrophil-Mediated Nanoparticles. Theranostics. 2017;7(13):3260-3275.
[42] HAN L, CAI Q, TIAN D, et al. Targeted drug delivery to ischemic stroke via chlorotoxin-anchored, lexiscan-loaded nanoparticles. Nanomedicine. 2016;12(7):1833-1842.
[43] LI M, LI J, CHEN J, et al. Platelet Membrane Biomimetic Magnetic Nanocarriers for Targeted Delivery and in Situ Generation of Nitric Oxide in Early Ischemic Stroke. ACS Nano. 2020;14(2):2024-2035.
[44] XU J, ZHANG Y, XU J, et al. Engineered Nanoplatelets for Targeted Delivery of Plasminogen Activators to Reverse Thrombus in Multiple Mouse Thrombosis Models. Adv Mater. 2020;32(4):e1905145.
[45] LEI XG, ZHU JH, CHENG WH, et al. Paradoxical Roles of Antioxidant Enzymes: Basic Mechanisms and Health Implications. Physiol Rev. 2016; 96(1):307-364.
[46] JIANG Y, BRYNSKIKH AM, S-MANICKAM D, et al. SOD1 nanozyme salvages ischemic brain by locally protecting cerebral vasculature. J Control Release. 2015;213:36-44.
[47] YUN X, MAXIMOV VD, YU J, et al. Nanoparticles for Targeted Delivery of Antioxidant Enzymes to the Brain after Cerebral Ischemia and Reperfusion Injury. J Cerebr Blood F Met. 2013;33(4):583-592.
[48] MANICKAM DS, BRYNSKIKH AM, KOPANIC JL, et al. Well-defined cross-linked antioxidant nanozymes for treatment of ischemic brain injury. J Control Release. 2012;162(3):636-645.
[49] GAO L, ZHUANG J, NIE L, et al. Intrinsic peroxidase-like activity of ferromagnetic nanoparticles. Nat Nanotechnol. 2007;2(9):577-583.
[50] WEI H, WANG E. Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes. Chem Soc Rev. 2013; 42(14):6060-6093.
[51] WU J, WANG X, WANG Q, et al. Nanomaterials with enzyme-like characteristics (nanozymes): next-generation artificial enzymes (II). Chem Soc Rev. 2019;48(4):1004-1076.
[52] KIM CK, KIM T, CHOI IY, et al. Ceria nanoparticles that can protect against ischemic stroke. Angew Chem Int Ed Engl. 2012;51(44):11039-11043.
[53] LIU CP, WU TH, LIN YL, et al. Tailoring Enzyme-Like Activities of Gold Nanoclusters by Polymeric Tertiary Amines for Protecting Neurons Against Oxidative Stress. Small. 2016;12(30):4127-4135.
[54] MU X, WANG J, LI Y, et al. Redox Trimetallic Nanozyme with Neutral Environment Preference for Brain Injury. ACS Nano. 2019;13(2):1870-1884.
[55] XI J, ZHANG R, WANG L, et al. A Nanozyme‐Based Artificial Peroxisome Ameliorates Hyperuricemia and Ischemic Stroke. Adv Func Mater. 2020:2007130.
[56] ZHANG K, TU M, GAO W, et al. Hollow Prussian Blue Nanozymes Drive Neuroprotection against Ischemic Stroke via Attenuating Oxidative Stress, Counteracting Inflammation, and Suppressing Cell Apoptosis. Nano Lett. 2019;19(5):2812-2823.
[57] LIU Y, AI K, JI X, et al. Comprehensive Insights into the Multi-Antioxidative Mechanisms of Melanin Nanoparticles and Their Application To Protect Brain from Injury in Ischemic Stroke. J Am Chem Soc. 2017;139(2):856-862.
[58] GAGE FH, TEMPLE S. Neural stem cells: generating and regenerating the brain. Neuron. 2013;80(3):588-601.
[59] LINDVALL O, KOKAIA Z. Stem Cell Research in Stroke. Stroke. 2011; 42(8):2369-2375.
[60] BALASUBRAMANIAN V, DOMANSKYI A, RENKO JM, et al. Engineered antibody-functionalized porous silicon nanoparticles for therapeutic targeting of pro-survival pathway in endogenous neuroblasts after stroke. Biomaterials. 2020;227:119556.
[61] JIAN WH, WANG HC, KUAN CH, et al. Glycosaminoglycan-based hybrid hydrogel encapsulated with polyelectrolyte complex nanoparticles for endogenous stem cell regulation in central nervous system regeneration. Biomaterials. 2018;174:17-30.
[62] BAKER EW, KINDER HA, WEST FD. Neural stem cell therapy for stroke: A multimechanistic approach to restoring neurological function. Brain Behav. 2019;9(3):e01214.
[63] HORIE N, PEREIRA MP, NIIZUMA K, et al. Transplanted Stem Cell-Secreted Vascular Endothelial Growth Factor Effects Poststroke Recovery, Inflammation, and Vascular Repair. Stem Cells. 2011;29(2): 274-285.
[64] JEONG CH, KIM SM, LIM JY, et al. Mesenchymal stem cells expressing brain-derived neurotrophic factor enhance endogenous neurogenesis in an ischemic stroke model. Biomed Res Int. 2014;2014:129145.
[65] BLISS T, GUZMAN R, DAADI M, et al. Cell transplantation therapy for stroke. Stroke. 2007;38(2 Suppl):817-826.
[66] LIU X, REN X, DENG X, et al. A protein interaction network for the analysis of the neuronal differentiation of neural stem cells in response to titanium dioxide nanoparticles. Biomaterials. 2010;31(11):3063-3070.
[67] SARAIVA C, TALHADA D, RAI A, et al. MicroRNA-124-loaded nanoparticles increase survival and neuronal differentiation of neural stem cells in vitro but do not contribute to stroke outcome in vivo. PLoS One. 2018;13(3):e0193609.
[68] NAZARIAN S, ABDOLMALEKI Z, TORFEH A, et al. Mesenchymal stem cells with modafinil (gold nanoparticles) significantly improves neurological deficits in rats after middle cerebral artery occlusion. Exp Brain Res. 2020;238(11):2589-2601.
[69] SAKATA H, NARASIMHAN P, NIIZUMA K, et al. Interleukin 6-preconditioned neural stem cells reduce ischaemic injury in stroke mice. Brain. 2012;135(11):3298-3310.
[70] BERNSTOCK JD, PERUZZOTTI-JAMETTI L, YE D, et al. Neural stem cell transplantation in ischemic stroke: A role for preconditioning and cellular engineering. J Cerebr Blood F Met. 2017;37(7):2314-2319.
[71] BERNSTOCK JD, PERUZZOTTI-JAMETTI L, LEONARDI T, et al. SUMOylation promotes survival and integration of neural stem cell grafts in ischemic stroke. EBioMedicine. 2019;42:214-224.
[72] JIANG XC, XIANG JJ, WU HH, et al. Neural Stem Cells Transfected with Reactive Oxygen Species-Responsive Polyplexes for Effective Treatment of Ischemic Stroke. Adv Mater. 2019; 31(10):e1807591.
[73] WANG C, LIN G, LUAN Y, et al. HIF-prolyl hydroxylase 2 silencing using siRNA delivered by MRI-visible nanoparticles improves therapy efficacy of transplanted EPCs for ischemic stroke. Biomaterials. 2019;197:229-243.
[74] MODO M, MELLODEW K, CASH D, et al. Mapping transplanted stem cell migration after a stroke: a serial, in vivo magnetic resonance imaging study. Neuroimage. 2004;21(1):311-317.
[75] BULTE JW. In vivo MRI cell tracking: clinical studies. AJR Am J Roentgenol. 2009;193(2):314-325.
[76] ZHANG F, DUAN X, LU L, et al. In Vivo Targeted MR Imaging of Endogenous Neural Stem Cells in Ischemic Stroke. Molecules. 2016; 21(9):1143.
[77] ZHANG L, WANG Y, TANG Y, et al. High MRI performance fluorescent mesoporous silica-coated magnetic nanoparticles for tracking neural progenitor cells in an ischemic mouse model. Nanoscale. 2013;5(10): 4506-4516.
[78] LIN BL, ZHANG JZ, LU LJ, et al. Superparamagnetic Iron Oxide Nanoparticles-Complexed Cationic Amylose for In Vivo Magnetic Resonance Imaging Tracking of Transplanted Stem Cells in Stroke. Nanomaterials. 2017;7(5):107.
[79] YUN S, SHIN TH, LEE JH, et al. Design of Magnetically Labeled Cells (Mag-Cells) for in Vivo Control of Stem Cell Migration and Differentiation. Nano Lett. 2018;18(2):838-845. |