[1] TSUKASAKI M, TAKAYANAGI H. Osteoimmunology: evolving concepts in bone-immune interactions in health and disease. Nat Rev Immunol. 2019;19(10):626-642.
[2] BERENDSEN AD, OLSEN BR. Bone development. Bone. 2015;80: 14-18.
[3] HUYNH NC, EVERTS V, PAVASANT P, et al. Inhibition of Histone Deacetylases Enhances the Osteogenic Differentiation of Human Periodontal Ligament Cells. J Cell Biochem. 2016;117(6):1384-1395.
[4] GALLINARI P, DI MARCO S, JONES P, et al. HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics. Cell Res. 2007;17(3):195-211.
[5] GREGORETTI IV, LEE YM, GOODSON HV. Molecular evolution of the histone deacetylase family: functional implications of phylogenetic analysis. J Mol Biol. 2004;338(1):17-31.
[6] GROZINGER CM, CHAO ED, BLACKWELL HE, et al. Identification of a class of small molecule inhibitors of the sirtuin family of NAD-dependent deacetylases by phenotypic screening. J Biol Chem. 2001; 276(42):38837-38843.
[7] DE RUIJTER AJ, VAN GENNIP AH, CARON HN, et al. Histone deacetylases (HDACs): characterization of the classical HDAC family. Biochem J. 2003;370(Pt 3):737-749.
[8] SMITH BC, HALLOWS WC, DENU JM. Mechanisms and molecular probes of sirtuins. Chem Biol. 2008;15(10):1002-1013.
[9] KEREMU A, AIMAITI A, LIANG Z, et al. Role of the HDAC6/STAT3 pathway in regulating PD-L1 expression in osteosarcoma cell lines. Cancer Chemother Pharmacol. 2019;83(2):255-264.
[10] HA M, KIM VN. Regulation of microRNA biogenesis. Nat Rev Mol Cell Biol. 2014;15(8):509-524.
[11] IORIO MV, PIOVAN C, CROCE CM. Interplay between microRNAs and the epigenetic machinery: an intricate network. Biochim Biophys Acta. 2010;1799(10-12):694-701.
[12] LI ZH, HU H, ZHANG XY, et al. MiR-291a-3p regulates the BMSCs differentiation via targeting DKK1 in dexamethasone-induced osteoporosis. Kaohsiung J Med Sci. 2020;36(1):35-42.
[13] GAO XL, CAO MG, AI GG, et al. Mir-98 reduces the expression of HMGA2 and promotes osteogenic differentiation of mesenchymal stem cells. Eur Rev Med Pharmacol Sci. 2018;22(11):3311-3317.
[14] SHEN GY, REN H, HUANG JJ, et al. Plastrum Testudinis Extracts Promote BMSC Proliferation and Osteogenic Differentiation by Regulating Let-7f-5p and the TNFR2/PI3K/AKT Signaling Pathway. Cell Physiol Biochem. 2018;47(6):2307-2318.
[15] FU YC, ZHAO SR, ZHU BH, et al. MiRNA-27a-3p promotes osteogenic differentiation of human mesenchymal stem cells through targeting ATF3. Eur Rev Med Pharmacol Sci. 2019;23(3 Suppl):73-80.
[16] 杨晓红,杨琨,廖立,等.微RNA-705对MC3T3-E1细胞成骨分化能力的影响[J].浙江大学学报(医学版),2016,45(6):575-580.
[17] LUO Y, CAO X, CHEN J, et al. MicroRNA-224 suppresses osteoblast differentiation by inhibiting SMAD4. J Cell Physiol. 2018;233(10): 6929-6937.
[18] LUO B, YANG JF, WANG YH, et al. MicroRNA-579-3p promotes the progression of osteoporosis by inhibiting osteogenic differentiation of mesenchymal stem cells through regulating Sirt1. Eur Rev Med Pharmacol Sci. 2019;23(16):6791-6799.
[19] FENG Y, WAN P, YIN L, et al. The Inhibition of MicroRNA-139-5p Promoted Osteoporosis of Bone Marrow-Derived Mesenchymal Stem Cells by Targeting Wnt/Beta-Catenin Signaling Pathway by NOTCH1. J Microbiol Biotechnol. 2020;30(3):448-458.
[20] HUANG Y, HOU Q, SU H, et al. miR‑488 negatively regulates osteogenic differentiation of bone marrow mesenchymal stem cells induced by psoralen by targeting Runx2. Mol Med Rep. 2019;20(4):3746-3754.
[21] ZHANG HG, WANG XB, ZHAO H, et al. MicroRNA-9-5p promotes osteoporosis development through inhibiting osteogenesis and promoting adipogenesis via targeting Wnt3a. Eur Rev Med Pharmacol Sci. 2019;23(2):456-463.
[22] COSKUN M, BJERRUM JT, SEIDELIN JB, et al. MicroRNAs in inflammatory bowel disease--pathogenesis, diagnostics and therapeutics. World J Gastroenterol. 2012;18(34):4629-4634.
[23] MOHANAKRISHNAN V, BALASUBRAMANIAN A, MAHALINGAM G, et al. Parathyroid hormone-induced down-regulation of miR-532-5p for matrix metalloproteinase-13 expression in rat osteoblasts. J Cell Biochem. 2018;119(7):6181-6193.
[24] ITOH T, FAIRALL L, MUSKETT FW, et al. Structural and functional characterization of a cell cycle associated HDAC1/2 complex reveals the structural basis for complex assembly and nucleosome targeting. Nucleic Acids Res. 2015;43(4):2033-2044.
[25] WATSON PJ, FAIRALL L, SCHWABE JW. Nuclear hormone receptor co-repressors: structure and function. Mol Cell Endocrinol. 2012;348(2): 440-449.
[26] BANTSCHEFF M, HOPF C, SAVITSKI MM, et al. Chemoproteomics profiling of HDAC inhibitors reveals selective targeting of HDAC complexes. Nat Biotechnol. 2011;29(3):255-265.
[27] CANTLEY MD, FAIRLIE DP, BARTOLD PM, et al. Inhibiting histone deacetylase 1 suppresses both inflammation and bone loss in arthritis. Rheumatology (Oxford). 2015;54(9):1713-1723.
[28] CHO YD, KIM BS, KIM WJ, et al. Histone acetylation together with DNA demethylation empowers higher plasticity in adipocytes to differentiate into osteoblasts. Gene. 2020;733:144274.
[29] LEE HW, SUH JH, KIM AY, et al. Histone deacetylase 1-mediated histone modification regulates osteoblast differentiation. Mol Endocrinol. 2006;20(10):2432-2443.
[30] ZHANG Y, MA C, LIU X, et al. Epigenetic landscape in PPARγ2 in the enhancement of adipogenesis of mouse osteoporotic bone marrow stromal cell. Biochim Biophys Acta. 2015;1852(11):2504-2516.
[31] LIU T, HOU L, ZHAO Y, et al. Epigenetic silencing of HDAC1 by miR-449a upregulates Runx2 and promotes osteoblast differentiation. Int J Mol Med. 2015;35(1):238-246.
[32] KUSHWAHA P, KHEDGIKAR V, SHARMA D, et al. MicroRNA 874-3p Exerts Skeletal Anabolic Effects Epigenetically during Weaning by Suppressing Hdac1 Expression. J Biol Chem. 2016;291(8):3959-3966.
[33] MAO G, ZHANG Z, HUANG Z, et al. MicroRNA-92a-3p regulates the expression of cartilage-specific genes by directly targeting histone deacetylase 2 in chondrogenesis and degradation. Osteoarthritis Cartilage. 2017;25(4):521-532.
[34] HUANG JH, XU Y, LIN FY. The inhibition of microRNA-326 by SP1/HDAC1 contributes to proliferation and metastasis of osteosarcoma through promoting SMO expression. J Cell Mol Med. 2020;24(18):10876-10888.
[35] BHASKARA S, KNUTSON SK, JIANG G, et al. Hdac3 is essential for the maintenance of chromatin structure and genome stability. Cancer Cell. 2010;18(5):436-447.
[36] MCGEE-LAWRENCE ME, CARPIO LR, SCHULZE RJ, et al. Hdac3 Deficiency Increases Marrow Adiposity and Induces Lipid Storage and Glucocorticoid Metabolism in Osteochondroprogenitor Cells. J Bone Miner Res. 2016;31(1):116-128.
[37] FEIGENSON M, SHULL LC, TAYLOR EL, et al. Histone Deacetylase 3 Deletion in Mesenchymal Progenitor Cells Hinders Long Bone Development. J Bone Miner Res. 2017;32(12):2453-2465.
[38] MENG F, LI Z, ZHANG Z, et al. MicroRNA-193b-3p regulates chondrogenesis and chondrocyte metabolism by targeting HDAC3. Theranostics. 2018;8(10):2862-2883.
[39] FU Y, ZHANG P, GE J, et al. Histone deacetylase 8 suppresses osteogenic differentiation of bone marrow stromal cells by inhibiting histone H3K9 acetylation and RUNX2 activity. Int J Biochem Cell Biol. 2014;54:68-77.
[40] CHEN W, CHEN L, ZHANG Z, et al. MicroRNA-455-3p modulates cartilage development and degeneration through modification of histone H3 acetylation. Biochim Biophys Acta. 2016;1863(12):2881-2891.
[41] MARTIN M, KETTMANN R, DEQUIEDT F. Class IIa histone deacetylases: regulating the regulators. Oncogene. 2007;26(37):5450-5467.
[42] NAKATANI T, CHEN T, JOHNSON J, et al. The Deletion of Hdac4 in Mouse Osteoblasts Influences Both Catabolic and Anabolic Effects in Bone. J Bone Miner Res. 2018;33(7):1362-1375.
[43] TAN K, PENG YT, GUO P. MiR-29a promotes osteogenic differentiation of mesenchymal stem cells via targeting HDAC4. Eur Rev Med Pharmacol Sci. 2018;22(11):3318-3326.
[44] LI Z, HASSAN MQ, JAFFERJI M, et al. Correction: Biological functions of miR-29b contribute to positive regulation of osteoblast differentiation. J Biol Chem. 2019;294(25):10018.
[45] XU D, GAO Y, HU N, et al. miR-365 Ameliorates Dexamethasone-Induced Suppression of Osteogenesis in MC3T3-E1 Cells by Targeting HDAC4. Int J Mol Sci. 2017;18(5):977.
[46] CHEN W, SHENG P, HUANG Z, et al. MicroRNA-381 Regulates Chondrocyte Hypertrophy by Inhibiting Histone Deacetylase 4 Expression. Int J Mol Sci. 2016;17(9):1377.
[47] WANG H, ZHANG H, SUN Q, et al. Chondrocyte mTORC1 activation stimulates miR-483-5p via HDAC4 in osteoarthritis progression. J Cell Physiol. 2019;234(3):2730-2740.
[48] LI P, WEI X, GUAN Y, et al. MicroRNA-1 regulates chondrocyte phenotype by repressing histone deacetylase 4 during growth plate development. FASEB J. 2014; 28(9): 3930-3941.
[49] WU G, YU W, ZHANG M, et al. MicroRNA-145-3p suppresses proliferation and promotes apotosis and autophagy of osteosarcoma cell by targeting HDAC4. Artif Cells Nanomed Biotechnol. 2018; 46(sup2):579-586.
[50] WEIN MN, SPATZ J, NISHIMORI S, et al. HDAC5 controls MEF2C-driven sclerostin expression in osteocytes. J Bone Miner Res. 2015;30(3): 400-411.
[51] LI H, XIE H, LIU W, et al. A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans. J Clin Invest. 2009;119(12):3666-3677.
[52] JIN Z, WEI W, DECHOW PC, et al. HDAC7 inhibits osteoclastogenesis by reversing RANKL-triggered β-catenin switch. Mol Endocrinol. 2013; 27(2):325-335.
[53] JENSEN ED, SCHROEDER TM, BAILEY J, et al. Histone deacetylase 7 associates with Runx2 and represses its activity during osteoblast maturation in a deacetylation-independent manner. J Bone Miner Res. 2008;23(3):361-372.
[54] ZHANG C, ZHANG Z, CHANG Z, et al. miR-193b-5p regulates chondrocytes metabolism by directly targeting histone deacetylase 7 in interleukin-1β-induced osteoarthritis. J Cell Biochem. 2019;120(8): 12775-12784.
[55] LI L, LIU W, WANG H, et al. Mutual inhibition between HDAC9 and miR-17 regulates osteogenesis of human periodontal ligament stem cells in inflammatory conditions. Cell Death Dis. 2018;9(5):480.
[56] LI CJ, CHENG P, LIANG MK, et al. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest. 2015;125(4):1509-1522.
[57] ZHAO YX, WANG YS, CAI QQ, et al. Up-regulation of HDAC9 promotes cell proliferation through suppressing p53 transcription in osteosarcoma. Int J Clin Exp Med. 2015;8(7):11818-11823.
[58] FALKENBERG KJ, JOHNSTONE RW. Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders. Nat Rev Drug Discov. 2014;13(9):673-691.
[59] RIMANDO MG, WU HH, LIU YA, et al. Glucocorticoid receptor and Histone deacetylase 6 mediate the differential effect of dexamethasone during osteogenesis of mesenchymal stromal cells (MSCs). Sci Rep. 2016;6:37371.
[60] WESTENDORF JJ, ZAIDI SK, CASCINO JE, et al. Runx2 (Cbfa1, AML-3) interacts with histone deacetylase 6 and represses the p21(CIP1/WAF1) promoter. Mol Cell Biol. 2002;22(22):7982-7992.
[61] HUANG S, WANG S, BIAN C, et al. Upregulation of miR-22 promotes osteogenic differentiation and inhibits adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells by repressing HDAC6 protein expression. Stem Cells Dev. 2012;21(13):2531-2540.
[62] VALENZUELA-FERNÁNDEZ A, CABRERO JR, SERRADOR JM, et al. HDAC6: a key regulator of cytoskeleton, cell migration and cell-cell interactions. Trends Cell Biol. 2008;18(6):291-297.
[63] LEE YS, LIM KH, GUO X, et al. The cytoplasmic deacetylase HDAC6 is required for efficient oncogenic tumorigenesis. Cancer Res. 2008; 68(18):7561-7569.
[64] KALUZA D, KROLL J, GESIERICH S, et al. Class IIb HDAC6 regulates endothelial cell migration and angiogenesis by deacetylation of cortactin. EMBO J. 2011;30(20):4142-4156.
[65] XU Y, WANG S, TANG C, et al. Upregulation of long non-coding RNA HIF 1α-anti-sense 1 induced by transforming growth factor-β-mediated targeting of sirtuin 1 promotes osteoblastic differentiation of human bone marrow stromal cells. Mol Med Rep. 2015;12(5):7233-7238.
[66] CHENG HL, MOSTOSLAVSKY R, SAITO S, et al. Developmental defects and p53 hyperacetylation in Sir2 homolog (SIRT1)-deficient mice. Proc Natl Acad Sci U S A. 2003;100(19):10794-10799.
[67] GABAY O, SANCHEZ C, DVIR-GINZBERG M, et al. Sirtuin 1 enzymatic activity is required for cartilage homeostasis in vivo in a mouse model. Arthritis Rheum. 2013;65(1):159-166.
[68] MERCKEN EM, MITCHELL SJ, MARTIN-MONTALVO A, et al. SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass. Aging Cell. 2014;13(5):787-796.
[69] 邓纯博, 刘林, 肖正俊, 等.骨质疏松小鼠骨组织中miR-21及Smad7的表达及其与骨密度的相关性[J].中国医科大学学报, 2019,48(1):44-47.
[70] 潘欣, 曾思良, 梁兴伦, 等.MicroRNA-195-5p调节Bmpr1α表达对骨髓间充质干细胞成脂分化的影响[J].同济大学学报(医学版), 2017,38(3):1-7+13.
[71] 陶云霞, 王亮亮, 候振扬, 等.微小RNA-106b通过调控核因子-κB受体活化因子配体/骨保护素对胶原诱导的小鼠关节炎骨质破坏的作用[J].中华实验外科杂志,2019,36(7):1243-1246.
[72] WANG L, HE J, XU H, et al. MiR-143 targets CTGF and exerts tumor-suppressing functions in epithelial ovarian cancer. Am J Transl Res. 2016;8(6):2716-2726.
[73] 徐泽, 黄威, 马锐祥, 等.miRNA-30e-5p抑制骨肉瘤细胞增殖、转移的机制研究[J].山西医科大学学报,2020,51(6):506-511.
[74] BRADLEY EW, MCGEE-LAWRENCE ME, WESTENDORF JJ. Hdac-mediated control of endochondral and intramembranous ossification[J]. Crit Rev Eukaryot Gene Expr. 2011;21(2):101-113.
[75] CHANG J, VARGHESE DS, GILLAM MC, et al. Differential response of cancer cells to HDAC inhibitors trichostatin A and depsipeptide[J]. Br J Cancer. 2012;106(1):116-125.
[76] SONG J, JIN EH, KIM D, et al. MicroRNA-222 regulates MMP-13 via targeting HDAC-4 during osteoarthritis pathogenesis. BBA Clin. 2015;3: 79-89.
[77] LAWLOR L, YANG XB. Harnessing the HDAC-histone deacetylase enzymes, inhibitors and how these can be utilised in tissue engineering. Int J Oral Sci. 2019;11(2):20.
[78] AUTIN P, BLANQUART C, FRADIN D. Epigenetic Drugs for Cancer and microRNAs: A Focus on Histone Deacetylase Inhibitors. Cancers (Basel). 2019;11(10):1530.
[79] SUN X, GUO Q, WEI W, et al. Current Progress on MicroRNA-Based Gene Delivery in the Treatment of Osteoporosis and Osteoporotic Fracture. Int J Endocrinol. 2019;2019:6782653.
|