中国组织工程研究 ›› 2013, Vol. 17 ›› Issue (2): 375-380.doi: 10.3969/j.issn.2095-4344.2013.02.034

• 组织构建学术探讨 tissue construction academic discussion • 上一篇    

作用于乳腺组织的近红外脉冲光

邓艳琼1,李文科1,万颖文2,李凯扬1   

  1. 1武汉大学物理科学与技术学院电子科学与技术系,湖北省武汉市  430072
    2武汉大学人民医院甲状腺乳腺外科,湖北省武汉市  430060
  • 收稿日期:2012-04-08 修回日期:2012-07-23 出版日期:2013-01-08 发布日期:2013-01-08
  • 通讯作者: 李凯扬,教授,武汉大学物理科学与技术学院电子科学与技术系,湖北省武汉市 430072 lky@whu.edu.cn
  • 作者简介:邓艳琼★,女,1987年生,汉族,武汉大学微电子学与固体电子学专业在读硕士,主要从事医疗器械开发方面的研究。dengyq@whu.edu.cn
  • 基金资助:

    武汉市“3551人才计划”项目资助(武新管[2010]210号)。

Revealing the near-infrared pulsed light in the breast

Deng Yan-qiong1, Li Wen-ke1, Wan Ying-wen2, Li Kai-yang1   

  1. 1 Department of Electronic Science and Technology, School of Physics and Technology, Wuhan University, Wuhan  430072, Hubei Province, China
    2 Department of Thyroid and Breast Surgery, Renmin Hospital of Wuhan University, Wuhan  430060, Hubei Province, China
  • Received:2012-04-08 Revised:2012-07-23 Online:2013-01-08 Published:2013-01-08
  • Contact: Li Kai-yang, Professor, Department of Electronic Science and Technology, School of Physics and Technology, Wuhan University, Wuhan 430072, Hubei Province, China lky@whu.edu.cn
  • About author:Deng Yan-qiong★, Studying for master’s degree, Department of Electronic Science and Technology, School of Physics and Technology, Wuhan University, Wuhan 430072, Hubei Province, China dengyq@whu.edu.cn
  • Supported by:

    Supported by: the “3551 Talents Scheme” of Wuhan City, No. [2010]210

摘要:

背景:传统诊断乳腺疾病的方法大多具有对人体有损伤和价格昂贵的弊端。近年来,通过研究乳腺组织的光学特性来诊断乳腺疾病的方法,因其具有安全无损、经济实惠的优点而受到一定的关注。
目的:分析近红外脉冲光作用于人体乳腺的组织光学特性的临床应用价值。
方法:利用760 nm和850 nm两种波长的近红外脉冲光穿透乳腺组织,对接收到的透射光进行两种波长的功率谱和互相关分析。
结果与结论:近红外脉冲光分别作用于健康乳腺和患病乳腺存在差别,正常、良性和恶性乳腺的互相关系数依次降低。初步临床研究表明:近红外脉冲光作用乳腺组织的光学特性研究有利于乳腺疾病的鉴别诊断和临床应用。

关键词: 组织构建, 组织构建学术探讨, 乳腺组织, 乳腺, 近红外脉冲光, 组织光学特性, 良性病变, 恶性病变, 功率谱分析, 互相关系数, 其他基金

Abstract:

BACKGROUND: The existing traditional diagnosis methods of breast diseases are mostly harmful and expensive to the human body. In recent years, diagnosis of breast diseases depends on the optical properties of the breast tissue, which has attracted more attention because of some advantages, such as safe, economical and practical condition.
OBJECTIVE: To study the clinical application of the optical properties of the breast tissue irradiated by near-infrared pulse light.
METHODS: 760 nm and 850 nm wavelength near-infrared pulsed lights irradiated the breast tissue, and the wavelength of these two kinds of transmitted lights was analyzed using power spectrum and cross-correlation analysis.
RESULTS AND CONCLUSION: There were differences between the healthy breast and unhealthy breast, the cross-correlation coefficient of normal, benign and malignant breast turned to reduce. Clinical studies have shown that the near-infrared pulsed light in the optical properties of breast tissue is useful to the differential diagnosis of breast disease.

Key words: tissue construction, academic discussion in tissue construction, breast tissue, breast, near infrared pulse light, tissue optical properties, benign lesion, malignant lesion, power spectrum analysis, cross-correlation coefficient, other grants-supported paper

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