中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (15): 2835-2842.doi: 10.3969/j.issn.1673-8225.2012.15.039

• 组织构建学术探讨 tissue construction academic discussion • 上一篇    下一篇

血管内皮生长因子与骨折愈合：SCI数据库10年资料检索分析*☆

陈俭波   

  1. 南京中医药大学，江苏省南京市  225300
  • 收稿日期:2012-02-10 修回日期:2012-03-28 出版日期:2012-04-08 发布日期:2012-04-08
  • 作者简介:陈俭波☆，男，1973年生，黑龙江省甘南县人，汉族，南京中医药大学中医骨伤科在读博士，主治中医师，主要从事骨与关节损伤的基础与临床研究。chchch.121212@163.com
  • 基金资助:

    江苏省常州市科技发展指导项目(CS2007905)。

Vascular endothelial growth factor in bone healing: Data analysis based on SCI database

Chen Jian-bo   

  1. Nanjing University of Chinese Medicine, Nanjing  225300, Jiangsu Province, China
  • Received:2012-02-10 Revised:2012-03-28 Online:2012-04-08 Published:2012-04-08
  • About author:Chen Jian-bo☆, Studying for doctorate, Attending physician, Nanjing University of Chinese Medicine, Nanjing 225300, Jiangsu Province, China chchch.121212@163.com
  • Supported by:

     the Science and Technology Development Item of Changzhou, Jiangsu Province, No. CS2007905*

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摘要：

背景：血管内皮生长因子在骨折愈合过程中起着重要的作用。
目的：利用SCI数据库文献检索和深度分析功能，对于血管内皮生长因子对骨折愈合的干预作用近10年文献资料趋势进行多角度的探讨分析。
设计：文献计量学分析。
资料提取：由第一作者以vascular endothelial growth factor/VEGF(血管内皮生长因子)；fracture(骨折)；及healing(愈合)为关键词检索SCI数据库2002-01/2011-12的相关文献，并将分析结果及资料导出，以文字和图表的形式进行统计和计量分析，描述其分布特征。
主要数据的判定指标：①检索结果数量。②发表文章年份分布。③国家地区分布。④机构信息。⑤文献类型分析。⑥来源期刊分析。⑦高被引频次文献分析。
入选标准：纳入标准：检索血管内皮生长因子对骨折愈合的干预作用相关研究的文献。文献类型包括研究原著、综述、会议记录及摘要、快报文章、编辑素材。排除标准：与文章目的无关的文献，大于10年较陈旧的文献，未发表的文章以及需电话追踪和手工检索逐一分析的文献。
主要数据判定指标：以文献的类型、出版时间、发表文献的作者分布、学科类别、机构分布、国家地区分布、来源期刊、文献被引情况进行相关分析。
结果：SCI数据库2002/2011收录的文献中共检索到180篇血管内皮生长因子对骨折愈合的干预作用研究相关的文献，研究原著以158篇位居首位，其中有9篇文献总被引次数超过50次，被确定为经典文献。在时间分布上，文献数量2002/2011总体呈上升趋势，来源出版物呈分散情况，其中Bone《骨》发表文献量21篇，占全部文献的11.67%。其次为Journal of Bone and Mineral Research《骨及矿物质研究》13篇。
结论：血管内皮生长因子对骨折愈合的干预作用是近几年的研究热点，中国在该领域的研究趋于成熟，并在国际数据库收录文献数量上占有重要位置。
关键词：血管内皮生长因子；骨折；愈合；干预；文献计量学
doi:10.3969/j.issn.1673-8225.2012.15.039

关键词: 血管内皮生长因子, 骨折, 愈合, 干预, 文献计量学

Abstract:

BACKGROUND: Vascular endothelial growth factor plays an important role in bone healing.
OBJECTIVE: To provide the valuable bibliometric analytical data addressing the effects of vascular endothelial growth factor on bone healing.
DESIGN: Bibliometric data analysis based on Science citation index (SCI) database within 10 years.
DATA RETRIEVAL: ①A search of related literatures was performed in SCI database using the key words of “vascular endothelial growth factor/VEGF, fracture, healing”. ②The data were analyzed. ③The data were output into pictures and tables to describe the results.
SELECTION CRITERIA: Original researches, reviews and conference proceedings were selected. Letters, editorials, proofreading, essays, short messaging and unpublished articles were excluded.
MAIN OUTCOME MEASUREMENTS: ①Numbers of the literatures; ②Publication year of the documents; ③Distribution of the countries; ④Distribution of the institutions; ⑤Document types; ⑥Analysis of source journals; ⑦Analysis of citation frequency.
RESULTS: A total of 180 papers associated with vascular endothelial growth factor in bone healing in SCI database were searched from January 2002 to December 2011, containing 158 articles and 22 other types of documents. Nine of the articles were cited more than 50 times and considered to be the classic references. Overall, the number of papers was gradually increasing. The Bone published the most papers (n=21, 11.67%), followed by Journal of Bone and Mineral Research (n=13). 
CONCLUSION: Vascular endothelial growth factor in bone healing is the hot spot in recent years. Researches of China in this field are gradually mature and have an important position, and China is important in the number of literature in international database.

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