中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (13): 2419-2422.doi: 10.3969/j.issn.1673-8225.2012.13.032

• 骨与关节学术探讨 academic discussion of the bone and joint • 上一篇    下一篇

骨损伤内固定植入物形状和结构与生物力学的关系★

杨君建   

  1. 北京工商大学体育部体质健康中心，北京市 100048
  • 收稿日期:2011-12-03 修回日期:2012-01-12 出版日期:2012-03-25 发布日期:2012-03-25
  • 作者简介:杨君建★，男，1975年生，四川省仁寿县人，汉族，2008年北京体育大学毕业，硕士，讲师，主要从事运动训练与康复保健学研究。wxlw77@126.com

Relationship of shape and structure of internal fixation implant to biomechanics following bone injury

Yang Jun-jian   

  1. Physique Health Center, Department of Physical Education, Beijing Technology and Business University, Beijing  100048, China
  • Received:2011-12-03 Revised:2012-01-12 Online:2012-03-25 Published:2012-03-25
  • About author:Yang Jun-jian★, Master, Lecturer, Physique Health Center, Department of Physical Education, Beijing Technology and Business University, Beijing 100048, China wxlw77@126.com

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摘要：

背景：实践证明内固定材料良好的生物力学性能对受损骨的治疗效果影响较大，而通过改善内固定材料的形状和结构可以实现较好的力学效果。
目的：以骨科置入内固定材料的生物力学特征为视角，分析与阐述骨科植入物的形状和结构与内固定效果的关系。
方法：应用计算机检索PubMed、维普和万方数据库中1990-01/2011-12关于骨损伤治疗及其内固定材料学方面的文章，在标题和摘要中以“骨，固定，形状，材料”或“bone，fixed，shape，material”为检索词进行检索，排除重复研究、普通综述或Meta分析类文章。初检得到156篇文献，根据纳入标准选择26篇文章进行综述。
结果与结论：骨科植入物材料的生物力学性能对骨的固定、骨血供以及成骨细胞的成长和再生起着重要的制约因素，而材料形状和结构的改变会对其生物力学性能产生较大的影响进而影响治疗效果。如何运用新工艺对骨科植入物材料的形状或结构进行改善，通过对其进行巧妙的物理改性以达到理想的内固定治疗效果应成为研究者关注的问题。
关键词：骨损伤；植入物；固定；形状；生物力学；材料
doi:10.3969/j.issn.1673-8225.2012.13.032

关键词: 骨损伤, 植入物, 固定, 形状, 生物力学, 材料

Abstract:

BACKGROUND: Good biomechanical property of internal fixation material has great effects on therapeutic outcomes of damaged bone. Good mechanics outcomes can be obtained by improving the shape and structure of internal fixation material.
OBJECTIVE: From the view angle of biomechanical feature of orthopedic implant internal fixation material, to analyze the correlation of shape and structure of orthopedic implant and internal fixation outcomes.
METHODS: We retrieved PubMed, Vip and Wanfang Database for articles concerning bone injury treatment and internal fixation material published from January 1990 to December 2011. The key words were “bone, fixation, shape, material”, which were searched in titles and abstracts. The articles addressing repetitive studies, common reviews or Meta analysis were excluded. A total of 156 articles were primarily obtained, and 29 articles were included according to inclusion criteria.
RESULTS AND CONCLUSION: Biomechanical property of orthopedic implants played an important inhibitory effect on bone fixation, bone blood supply, growth and regeneration of osteoblasts. Changes in material shape and structure would produce great effects on biomechanical property, and further affected therapeutic outcomes. How to use new technology to improve shape and structure of orthopedic implant material, and to perform physical modification and to reach ideal internal fixation therapeutic outcomes, has become a focused project by researchers.

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