中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (25): 4665-4668.doi: 10.3969/j.issn.1673-8225.2011.25.026

• 生物材料综述 biomaterial review • 上一篇    下一篇

玉米醇溶蛋白的物理化学改性

吴国际1,吕长波2,鲁传华3,林  腾3   

  1. 1 安徽省庐江县中医院,安徽省庐江县 231500;2 安徽国大药房连锁有限公司,安徽省合肥市 230038;3 安徽中医学院药学院,安徽省合肥市 230031
  • 收稿日期:2010-12-16 修回日期:2011-02-19 出版日期:2011-06-18 发布日期:2014-01-10
  • 通讯作者: 鲁传华,硕士,教授。安徽中医学院药学院,安徽省合肥市 230031 lchchem@126.com
  • 作者简介:吴国际,男,1973年生,安徽庐江县人,汉族,2004年安徽中医学院毕业,主管中药师,主要从事药物新剂型方面的研究。 sylt214@139.com

Physical and chemical modification of zein

Wu Guo-ji1, Lü Chang-bo2, Lu Chuan-hua3, Lin Teng3   

  1. 1Lu Jiang Hospital of Traditional Chinese Medicine, Lujiang Country  231500, Anhui Province, China; 2National Pharmacy Chain Co., Ltd. , Hefei  230038, Anhui Province, China; 3College of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei  230031, Anhui Province, China
  • Received:2010-12-16 Revised:2011-02-19 Online:2011-06-18 Published:2014-01-10
  • Contact: Lu Chuan-hua, Master, Professor, College of Pharmacy, Anhui University of Traditional Chinese Medicine, Hefei 230031, Anhui Province, China lchchem@126.com
  • About author:Wu Guo-ji, Pharmacist of traditional Chinese medicine-in-charge, Lu Jiang Hospital of Traditional Chinese Medicine, Lujiang Country 231500, Anhui Province, China sylt214@139.com

摘要:

背景:玉米醇溶蛋白作为缓控释材料和生物可降解药用辅料在药剂学领域有着广泛的应用。
目的:对玉米醇溶蛋白的物理化学改性方法进行综合分析。
方法:应用计算机检索CNKI和PubMed数据库中1998-01/2010-10关于玉米醇溶蛋白的文章,在标题和摘要中以“玉米醇溶蛋白,玉米朊,改性,接枝”或“ZEIN,Modification,Graft”为检索词进行检索。选择文章内容与玉米醇溶蛋白改性研究相关,同一领域文献则选择近期发表或发表在权威杂志文章。
结果与结论:对玉米醇溶蛋白的改性研究进行总结有利于指导玉米醇溶蛋白的改性研究,从而增加玉米醇溶蛋白在药物制剂,生物医学工程方面的利用价值。

关键词: 玉米醇溶蛋白, 玉米朊, 物理, 化学, 改性, 进展

Abstract:

BACKGROUND: Zein has been widely used as a controlled release medicinal materials and biodegradable materials in the pharmaceutical field.
OBJECTIVE: To review the research progresses on physical and chemical modification method of zein.
METHODS: A computer-based online search of the articles related to zein from CNKI database and PubMed database was performed with the key words “zein, mordification, graft” both in Chinese and in English. The articles related to the research on the modification zein were selected; articles in the same circle published in recent years or in authorized journals.
RESULTS AND CONCLUSION: The modification of zein has been reviewed and which will be helpful to guide the research on modification of zein, so as to increase utility value of zein on the subjects of pharmaceutics and biomedical engineering.

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