中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (2): 364-367.doi: 10.3969/j.issn.1673-8225.2011.02.043

• 组织构建循证医学 evidence-based medicine in tissue construction • 上一篇    下一篇

腹腔镜与开腹手术对直肠癌患者术后性功能及膀胱功能影响的系统评价

吴忠亮1，姚  南1，移  康1，2，郑  鹏1   

  1. 1兰州大学第一临床医学院普通外科，甘肃省兰州市 730000
    2兰州大学循证医学中心，甘肃省兰州市 730000
  • 收稿日期:2010-07-25 修回日期:2010-08-19 出版日期:2011-01-08 发布日期:2011-01-08
  • 通讯作者: 姚南，主任医师，副教授，硕士生导师，兰州大学第一临床医学院普通外科，甘肃省兰州市 730000 yaonanwzl@163.com
  • 作者简介:吴忠亮★，男，1977年生，苗族，兰州大学在读硕士，主要从事肛肠外科方面的研究。 wuzhongly@163.com

Laparoscopic versus open surgery effects on sexual function and bladder function of patients with rectal cancer: A systematic review  

Wu Zhong-liang1, Yao Nan1, Yi Kang1, 2, Zheng Peng1   

  1. 1Department of General Surgery, the First Hospital of Lanzhou University, Lanzhou  730000, Gansu Province, China
    2Center for Evidence-Based Medicine, Lanzhou University, Lanzhou  730000, Gansu Province, China
  • Received:2010-07-25 Revised:2010-08-19 Online:2011-01-08 Published:2011-01-08
  • Contact: Yao Nan, Chief physician, Associate professor, Master’s supervisor, Department of General Surgery, the First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China yaonanwzl@163.com
  • About author:Wu Zhong-liang★, Studying for master’s degree, Department of General Surgery, the First Hospital of Lanzhou University, Lanzhou 730000, Gansu Province, China wuzhongly@163.com

PDF

466

被引次数

31

摘要：

背景：腹腔镜手术治疗直肠癌在安全性及有效方面均达到或优于传统开腹手术，但可能引起性功能及膀胱功能障碍，而传统开腹术后性功能及膀胱功能障碍发生报道也存在争议。
目的：比较腹腔镜手术与开腹手术对直肠癌患者术后性功能及膀胱功能的影响。
方法：计算机检索PubMed，EMbase，Cochrane library，中国生物医学文献数据库、万方数据库、中国期刊全文数据库、中文科技期刊全文数据库，收集腹腔镜手术对比开腹手术治疗直肠癌患者的随机对照试验。由2名研究者独立按照纳入标准筛选文献、提取资料并交叉核对，采用Cochrane系统评价员手册4.2.6文献质量评价标准评价纳入研究质量，用RevMan 5.0软件进行 Meta分析。
结果与结论：共纳入3个研究，共计347例患者。结果显示与开腹手术比较，腹腔镜术后无论是男性患者或女性患者总在性功能障碍、膀胱功能障碍方面无显著性差异，但尚需要多中心大样本的随机对照试验进一步证实。

关键词: 结直肠癌, 腹腔镜, 开腹手术, 性功能, 膀胱功能, 系统评价

Abstract:

BACKGROUND: The laparoscopic surgery exhibit superiority to traditional open surgery in safety and effectiveness in the treatment of rectal cancer, but it may result in sexual and bladder functional disorders. Whether traditional open surgery can lead to sexual and bladder functional disorders remain in dispute. 
OBJECTIVE: To compare the effect of laparoscopic and open surgery on sexual function and bladder function in treatment of rectal cancer.
METHODS: Literatures related to randomized controlled trials in English and Chinese on the comparison between the sexual function and bladder function after laparoscopic and open surgery in rectal cancer from EMbase, PubMed, CJFD, CBM, Wanfang, CSFD Data were extracted and methodological quality were evaluated by two reviewers independently with designed extraction form. The Cochrane Collaboration’s RevMan 5.0 software was used for data analyses.
RESULTS AND CONCLUSION: A total of 3 studies involving 347 patients were included. The results of meta-analyses showed that, there were not significantly different between the laparoscopic and open surgery for rectal cancer in overall sexual function and bladder function, but the results required further investigation. 

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