中国组织工程研究

中国组织工程研究

• 生物材料临床实践 clinical practice of biomaterials • 上一篇    下一篇

羟基磷灰石材料义眼台植入25例：传统与改良方法的比较

张小广，刘小琴，周  琪，吴  将   

  1. 解放军兰州军区空军机关医院眼科，甘肃省兰州市  730020
  • 出版日期:2010-11-19 发布日期:2010-11-19
  • 作者简介:张小广，男，1966年生，山西省晋城市人，汉族，1989年空军吉林医学院毕业，副主任医师；主要从事白内障及活动性义眼植入方面的研究。 caozengyu@tom.com

Hydroxyapatite artificial eye implantation in 25 cases: A comparison of traditional method and improved method

Zhang Xiao-guang, Liu Xiao-qin, Zhou Qi, Wu Jiang   

  1. Department of Ophthalmology, Air-force Hospital of Lanzhou Military Area Command of Chinese PLA, Lanzhou   730020, Gansu Province, China
  • Online:2010-11-19 Published:2010-11-19
  • About author:Zhang Xiao-guang, Associate chief physician, Department of Ophthalmology, Air-force Hospital of Lanzhou Military Area Command of Chinese PLA, Lanzhou 730020, Gansu Province, China caozengyu@tom.com

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摘要：

背景：随着义眼台植入材料的逐渐改善，义眼台植入方法成为义眼台是否暴露的关键。
目的：通过对比改良的羟基磷灰石义眼台植入而减少常规术式植入后的并发症，探讨眼内容物剜出联合羟基磷灰石义眼台植入后义眼台暴露的机制，以提高治疗水平。
方法：纳入患者25例，按照不同的手术方式将患者随机分配，其中采用传统术式14例(14只眼)，手术眼均行眼内容物剜出加羟基磷灰石义眼台植入；改良术式11例(11只眼)，手术眼均行眼内容物剜出加肌锥内义眼台植入双层巩膜加固。观察义眼台暴露情况以及材料宿主反应情况。
结果与结论：传统手术组共暴露8例，改良手术组共暴露1例，经校正卡方检验差异有显著性意义(χ2=4.264，P=0.039 < 0.05)。结果提示：改良羟基磷灰石义眼台植入，术式简单，明显减少了义眼台暴露问题。

关键词: 羟基磷灰石, 义眼, 双层巩膜, 植入方法, 材料

Abstract:

BACKGROUND: With improvement of artificial eye material, the method of artificial eye implantation is critical for artificial eye exposure.
OBJECTIVE: To study a new method of hydroxyapatite (HA) artificial eye implantation with less complications after surgery than the common operation, and to explore the mechanism underlying artificial eye exposure after eye content enucleation and HA artificial eye implantation, so as to elevate the treatment standard.
METHODS: Twenty-five patients were divided randomly into two groups according to surgical approach. In traditional approach group, 14 patients (14 eyes) were treated with eye enucleation and HA artificial eye implantation, while in modified approach group, 11 eyes underwent eye enucleation and double-sclera covered hydroxyapatite implantation in muscle cone. The rates of artificial eye exposure and materials-host reaction were compared and analyzed between two groups.
RESULTS AND CONCLUSION: Artificial eyes of traditional approach group were exposed in 8 cases, and that of modified approach group was exposed in 1 case. There were significant differences between the two group by correct Chi-square test  (χ2=4.264, P=0.039 < 0.05). Modified HA artificial eye implantation is a good method with simple operation and less artificial eye exposure.

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