中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (38): 7209-7212.doi: 10.3969/j.issn.1673-8225.2010.38.044

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

生物性可吸收缝线在妇产科临床治疗中的应用

于  波，何  玲   

  1. 辽河油田中心医院妇产科，辽宁省盘锦市  124010
  • 出版日期:2010-09-17 发布日期:2010-09-17
  • 作者简介:于波，女，1971年生，辽宁省盘锦市人，汉族，1993年南京医学院毕业，主治医师，主要从事妇产科临床研究。

Biological absorbable surgical suture in clinical treatment of obstetrics and gynecology department

Yu Bo, He Ling   

  1. Department of Obstetrics and Gynecology, Center Hospital of Liaohe Oil Field, Panjin   124010, Liaoning Province, China
  • Online:2010-09-17 Published:2010-09-17
  • About author:Yu Bo, Attending physician, Department of Obstetrics and Gynecology, Center Hospital of Liaohe Oil Field, Panjin 124010, Liaoning Province, China

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467

被引次数

85

摘要：

目的：总结近年可吸收缝线在妇产科治疗中的应用现状。
方法：由作者应用计算机检索维普数据库中与可吸收治疗缝线在妇产科治疗有关的文章，检索时限1998-01/2009-10。检索关键词：生物性可吸收缝线；妇产科；应用。纳入标准：①生物性可吸收缝线与妇产科治疗有关的文章。②实验结果叙述与材料有关的应用问题。排除标准：重复研究或较陈旧文献。根据纳入排除标准共保留相关文献23篇。
结果：可吸收缝线包括天然及合成高分子材料，如羊肠线、真丝线、聚乳酸及聚乙醇酸等，可吸收缝线主要用于人体内部组织的缝合，在一段时间内被人体吸收，避免拆除缝线。这类缝线以DEXOU(PGA)为主要代表，具有较强的张力强度，良好的操作性能，并具有材料均一性，稳定性、无毒性、无胶原性、无抗原性及无致癌性，还有较强的抗酸和抗感染作用，最终可被水解和吸收，是妇产科手术缝合的最佳材料，它解决了肠线的低张力强度，高组织反应的缺点，并最终将取代丝线和肠线，成为理想的妇产科手术用线。
结论：由天然及合成高分子材料制成的医用缝线一般能满足手术中的使用要求，医生可根据其不同特点及临床经验优选。

关键词: 生物性可吸收缝线, 妇产科, 生物相容性, 张力强度, 生物材料

Abstract:

OBJECTIVE: To summarize the application progress of absorbable sutures in obstetrics and gynecology treatment in recent years.
METHODS: A computer research of VIP database from January 1998 to October 2009 was performed for articles about the absorbable suture in treatment of obstetrics and gynecology department, using the key words of “bio-absorbable suture; Department of Obstetrics and Gynecology; application” in Chinese. Inclusion criteria: ① Articles correlate with biological absorbable sutures in treatment of obstetrics and gynecology. ② The results described the application of materials. Exclusion criteria: repeated studies or outdated literatures. According to the inclusion and exclusion criteria, 23 literatures were involved in the analysis.
RESULTS: The absorbable suture includes natural and synthetic polymer materials, such as chorda chirurgicalis, natural silk, polylactic acid and polyglycolic acid, absorbable suture is mainly used for human internal tissue suture, can be absorbed by human body within certain period of time, avoiding dermal sutures removal. Such suture is predominant by DEXOU (PGA), which has strong tensile strength, good operational performance, material homogeneity and stability, has no toxicity, collagen, antigenicity or carcinogenicity, and exhibits strong anti-acid and anti-infection effect, ultimately can be hydrolyzed and absorbed, it is the optimal material for surgical suture in obstetrics and gynecology department. It solves the low tensile strength and high tissue response of chorda chirurgicalis, and will eventually replace natural silk and chorda chirurgicalis, to become the ideal surgical suture in obstetrics and gynecology department.
CONCLUSION: The medical suture made of natural and synthetic polymer materials generally meet the surgical requirements, the doctors may choose the materials according to different characteristics and clinical experience.　

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