中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (38): 7165-7168.doi: 10.3969/j.issn.1673-8225.2010.38.033

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

人工生物材料及组织工程学手段修复腕关节韧带损伤

王  睿   

  1. 河南工程技术学校运动人体科学实验室，河南省焦作市 454000
  • 出版日期:2010-09-17 发布日期:2010-09-17
  • 作者简介:王睿★，男，1967年生，汉族，河南省焦作市人，1989年河南师范大学毕业，硕士，主要从事运动人体科学方面的研究。 sqh@hpu.edu.cn

Artificial biomaterials and tissue engineering technologies for repair of wrist articular ligament injury

Wang Rui   

  1. Laboratory of Human Movement Science, Henan Engineering Technical School, Jiaozuo   454000, Henan Province, China
  • Online:2010-09-17 Published:2010-09-17
  • About author:Wang Rui★, Master, Laboratory of Human Movement Science, Henan Engineering Technical School, Jiaozuo 454000, Henan Province, China sqh@hpu.edu.cn

PDF

401

被引次数

3

摘要：

目的：总结分析人工生物材料干预腕关节韧带损伤的特点。
方法：作者应用计算机检索PubMed数据库(http://www.ncbi.nlm.nih.gov/PubMed)及CNKI数据库(www.cnki.net/ index.htm)，在标题和摘要中以“腕关节，韧带，康复，治疗”或“Wrist Joint，Ligament，Rehabilitation，Treatment”为检索词进行检索。选择文章内容与腕关节韧带损伤与治疗手段、材料学特点、生物相容性及其应用效果相关，同一领域文献则选择近期发表或发表在权威杂志的文章，共纳入22篇文献。
结果：腕关节属于非常复杂的连接系统，由于腕关节生理结构及其生物力学的特殊性，体育运动中腕关节韧带损伤较为常见。目前，国内外已对腕关节韧带做过较多的解剖学、组织学及生物力学特性的研究，但针对腕关节韧带损伤后运用人工生物材料及组织工程学手段修复或重建方面的报告甚为少见。

结论：随着细胞生物学和分子生物学方法和技术的进步，韧带组织损伤修复研究进入了崭新阶段，人工生物材料及组织工程学的兴起为腕关节韧带损伤后的治疗与康复措施提供了新的研究方向。

关键词: 腕关节, 韧带, 损伤, 康复, 治疗, 组织工程, 支架, 生物材料

Abstract:

OBJECTIVE: To summarize and analyze the characteristics of artificial biomaterials intervention for wrist articular ligament injury.
METHODS: A computer search was performed on PubMed database (http://www.ncbi.nlm.nih.gov/PubMed) and CNKI database (www.cnki.net / index.htm), using key words of "wrist joint, ligament, rehabilitation, treatment" in English or in Chinese in the titles and abstracts. Articles related to wrist articular ligament injury and treatment, material science characteristics, biocompatibility and its application effect were selected, those recently published or published in the authority journals were preferred to the same field, a total of 22 literatures were included.
RESULTS: The wrist joint is a very complex connection system, due to wrist joint physiological structure and biomechanical complexity, exercise-induced wrist ligament injury is common. At present, many studies have been performed addressing wrist ligament anatomy, histology and biomechanics, but few reports the use of artificial biomaterials and tissue engineering means to repair or reconstruct the wrist ligament injury.
CONCLUSION: With the advances in cell biology and molecular biology methods and technology, ligament injury repair research has entered a new stage, artificial biomaterials and tissue engineering provide a new research direction for the treatment and rehabilitation measures of wrist articular ligament injury.

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