中国组织工程研究

中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (2): 237-239.doi: 10.3969/j.issn.1673-8225.2010.02.011

• 组织构建循证医学 evidence-based medicine in tissue construction • 上一篇    下一篇

软组织侧貌修复过程中拔牙与非拔牙矫治影响的Meta分析　

刘泽萍，陈婷婷，李贵凤，姜思聪，邹淑娟   

  1. 四川大学华西口腔医学院正畸科   四川省成都市 610041
  • 出版日期:2010-01-08 发布日期:2010-01-08
  • 通讯作者: 邹淑娟，教授，博士生导师，四川大学华西口腔医学院正畸科，四川省成都市 610041 shujuanzou@yahoo.com.cn
  • 作者简介:刘泽萍★，女，1983年生，汉族，广东省潮州市人，四川大学华西口腔医学院在读硕士，主要从事错颌畸形的机制及治疗研究。 angellzpyyg@yahoo.com.cn
  • 基金资助:

    四川省科技厅软科学项目(2008 ZR0160)*

Meta analysis of soft tissue profile repair in patients treated with and without premolar extraction

Liu Ze-ping, Chen Ting-ting, Li Gui-feng, Jiang Si-cong, Zou Shu-juan   

  1. Department of Stomatology, West China College, Sichuan University, Chengdu   610041, Sichuan Province, China
  • Online:2010-01-08 Published:2010-01-08
  • Contact: Zou Shu-juan, Professor, Doctoral supervisor, Department of Stomatology, West China College, Sichuan University, Chengdu 610041, Sichuan Province, China shujuanzou@yahoo.com.cn
  • About author:Liu Ze-ping★, Studying for master’s degree, Department of Stomatology, West China College, Sichuan University, Chengdu 610041, Sichuan Province, China angellzpyyg@yahoo.com.cn
  • Supported by:

    Soft Science Program of Sichuan Provincial Science and Technology Department, No. 2008ZR0160*

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摘要：

目的：分析面部软组织侧貌修复过程中拔牙与非拔牙矫治的影响效应。
方法：以正畸矫治，拔牙矫治，软组织侧貌，orthodontics, corrective， tooth extraction，soft tissue profile为检索关键词，应用计算机检索近10年中国期刊网全文数据库、万方数据库、中文科技期刊全文数据库、CBM文章库、Medline(ovid)、 Science direct 以及手工检索并辅以文章追溯的方法收集国内、国外学者10年内公开发表的有关拔牙与非拔牙矫治软组织侧貌比较的文献。运用meta分析技术对拔牙与非拔牙矫治前后上下唇与审美平面及软组织平面的距离进行综合定量分析，根据资料异质性检验，采用固定效应模型及随机效应模型，计算合并加权均数差及其95%CI。使用Revman 5.0进行数据处理。
结果：共纳入文献5篇，共纳入患者356例。资料异质性检验显示，下唇与审美平面及软组织平面距离变化的异质性检验I2<50%，没有异质性，采用固定效应模型。上唇与审美平面及软组织平面距离>50%，具有异质性，采用随机效应模型。Meta分析结果显示，除上唇与审美平面距离外，上唇与软组织平面、下唇与审美平面及软组织平面距离合并加权均数差及95%CI均具有显著性意义。
结论：拔牙矫治明显减小了下唇与审美平面、软组织平面的距离以及上唇与软组织平面的距离。

关键词: 正畸矫治, 拔牙矫治, 软组织侧貌, Meta 分析

Abstract:

OBJECTIVE: To analyze the impact of extraction and nonextraction in soft tissue profile repair.
METHODS: Databases of CNKI, Wanfang, VIP Chinese Periodical Database, CBM, Medline (ovid) and Science direct had been searched for studies of soft tissue profile after orthodontic treatment with and without extractions published in recent decade, with orthodontics, corrective, tooth extraction, soft tissue profile as key words. Hand searching was also done to obtain any further information about the studies. Meta analysis was used to comprehensively quantitatively analyze the upper (lower) lip with esthetic plane and soft tissue plane before and after extraction and nonextraction treatment. According to homogeneity test, fixed effect model and random effect model were adopted to calculate weighted mean difference (WMD) and 95% confidence interval (95% CI). Revman 5.0 was used for data management.
RESULTS: Five studies with 356 patients were included. Homogeneity test showed that lower lip-esthetic line and lower lip-soft tissue line I2 < 50%, without heterogeneity, so fixed effect model was adopted. Upper lip-esthetic line and upper lip-soft tissue line were more than 50%, indicating heterogeneity, so random effect model was adopted. Result of meta-analysis showed that, the WMD value and 95% CI of lower lip-esthetic line, lower lip-soft tissue line, and upper lip-soft tissue line has statistically significance.
CONCLUSION: The extraction treatment significantly decreased the distance of lower lip-esthetic line, lower lip-soft tissue line, and upper lip-soft tissue line.

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