中国组织工程研究 ›› 2022, Vol. 26 ›› Issue (29): 4709-4715.doi: 10.12307/2022.843

• 组织构建综述 tissue construction review • 上一篇    下一篇


孔凡明1,朱苗苗1,米  靖1,马  杰2   

  1. 1北京体育大学竞技体育学院,北京市  100084;2中国戏曲学院体育部,北京市  100073
  • 收稿日期:2021-10-26 接受日期:2021-12-10 出版日期:2022-10-18 发布日期:2022-03-28
  • 通讯作者: 米靖,博士,教授,博士生导师,北京体育大学竞技体育学院运动训练学教研室,北京市 100084
  • 作者简介:孔凡明,男,1993年生,山东省菏泽市人,汉族,北京体育大学在读博士,主要从事运动与能量代谢方面的研究。
  • 基金资助:

Application enlightenment of exercise and fat oxidation kinetic characteristics

Kong Fanming1, Zhu Miaomiao1, Mi Jing1, Ma Jie2   

  1. 1Sport Coaching College, Beijing Sport University, Beijing 100084, China; 2Sports Department, National Academy of Chinese Theatre Arts, Beijing 100073, China
  • Received:2021-10-26 Accepted:2021-12-10 Online:2022-10-18 Published:2022-03-28
  • Contact: Mi Jing, PhD, Professor, Doctoral supervisor, Sport Coaching College, Beijing Sport University, Beijing 100084, China
  • About author:Kong Fanming, PhD candidate, Sport Coaching College, Beijing Sport University, Beijing 100084, China
  • Supported by:
    Beijing Sport University School-level Project, Nos. 2018PT007 and 20211021; New Century Excellent Talents Program of the Ministry of Education, No. [2013] 47



方法:通过中国知网(CNKI)、百链云图书馆、PubMed和EBSCO运动科学全文等中英文数据库及Researcher、ResearchGate学术社交平台,选取“运动;脂肪氧化;脂肪动员;脂肪代谢;减肥”及“exercise;fat metabolism;fat energy ratio;fat oxidation rate”等作为检索词分别进行中文及英文组合检索,对最终纳入的相关文献进行归类、汇总、总结与提炼。
结果与结论:①脂肪氧化动力学特征是一个复杂的非线性过程,主要包括脂肪供能比例和脂肪氧化率两个方面,并受运动强度、运动时间、运动方式、运动水平、运动习惯和体成分等因素的影响,上述各因素相互关联、相互制约,并呈现出阶段性变化特征。②运动调控脂肪氧化的分子生物学机制已较为成熟,但乳酸抑制脂肪氧化的生物学机制还不完全清楚。③为提高减肥效果,建议增加每日运动量,但受能量保护机制的影响,运动减肥的时间并非越长越好。建议后续加强运动调控脂肪氧化的基础应用性研究,借助蛋白组学、基因组学和免疫组学等手段,在器官系统和细胞分子水平上,从神经调节、免疫系统控制、骨骼肌代谢、线粒体适应、肠道菌群活性以及外泌体释放等方面入手寻找科学证据,探寻相关生物学机制。 (孔凡明) 


关键词: 运动, 能量代谢, 脂肪代谢, 脂肪供能比, 脂肪氧化率

Abstract: BACKGROUND: At present, reducing fat and losing weight has become an eternal topic. Exercise is an important means of lowering fat, and exploring the factors that affect fat metabolism during exercise has become a research hotspot. 
OBJECTIVE: To explore the effects of exercise style, exercise intensity, and exercise time on the kinetic characteristics of fat oxidation, summarize the biological mechanism of exercise regulating fat oxidation, explore the application enlightenment of reasonable exercise prescriptions in the prevention and treatment of obesity and other metabolic diseases, and look forward to future research directions in the field. 
METHODS: Literature retrieval was conducted in Chinese and English databases such as China Knowledge Network (CNKI), Bailian Cloud Library, PubMed and EBSCO Sports Science Full Text and Researcher and ResearchGate academic social platforms. The search terms included “exercise; fat metabolism; fat energy ratio; fat oxidation rate” in Chinese and English. After initial search, relevant documents were classified, summarized, and refined.
RESULTS AND CONCLUSION: Fat oxidation kinetics is a complex non-linear process, which mainly includes two aspects - fat energy supply ratio and fat oxidation rate, and is affected by exercise intensity, exercise time, exercise mode, exercise level, exercise habits, and body composition. The above-mentioned factors are interrelated and interacted, which experience changes in stages. The molecular biological mechanism of exercise regulating fat oxidation is relatively mature, but the biological mechanism of lactic acid inhibiting fat oxidation is not fully understood. To strengthen the weight loss effect, it is recommended to increase the amount of daily exercise. However, due to the influence of energy protection mechanism, a longer exercise does not indicate a better effect on weight loss. Further studies should be strengthened on the basic application of exercise to control fat oxidation. With the help of proteomics, genomics, and immunoomics tools, we can search for scientific evidence and explore relevant biological mechanisms at the organ system and cell molecular levels, in terms of neuromodulation, immune system control, skeletal muscle metabolism, mitochondrial adaptation, intestinal flora activity and exosomal release.

Key words: exercise, energy metabolism, fat metabolism, fat energy ratio, fat oxidation rate