中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (39): 7317-7321.doi: 10.3969/j.issn.2095-4344.2012.39.021

• 骨与关节综述 bone and joint review • 上一篇    下一篇

镁及镁合金植入体在骨科临床中的应用与进展

谢兴文1，黄 晋2，李 宁2，许 伟3，胡 彬2，徐世红2   

  1. 1甘肃省中医药研究院，甘肃省兰州市 730050
    2甘肃中医学院，甘肃省兰州市 730000
    3甘肃省中医学院，甘肃省兰州市 730050
  • 收稿日期:2011-12-17 修回日期:2012-01-19 出版日期:2012-09-23 发布日期:2012-09-23
  • 通讯作者: 谢兴文，博士，硕士生导师，副主任医师，副院长，甘肃省中医药研究院，甘肃省兰州市 730050 827975272@qq.com
  • 作者简介:谢兴文☆，男，1972年生，甘肃省天水市人，汉族，2006年上海中医药大学毕业，博士，副主任医师，主要从事中医药防治骨伤科疾病的相关研究。 827975272@qq.com

Progress of magnesium ions and magnesium alloy implant application in the clinical orthopaedics

Xie Xing-wen1, Huang Jin2, Li Ning2, Xu Wei3, Hu Bin2, Xu Shi-hong2   

  1. 1Institute of Traditional Chinese Medicine of Gansu Province, Lanzhou 730050, Gansu Province, China
    2Gansu Provincial Hospital of Traditional Chinese Medicine Lanzhou 730000, Gansu Province, China
    3Gansu College of Traditional Chinese Medicine Lanzhou 730050, Gansu Province, China
  • Received:2011-12-17 Revised:2012-01-19 Online:2012-09-23 Published:2012-09-23
  • Contact: Xie Xing-wen, Doctor, Master’s supervisor, Associate chief physician, Institute of Traditional Chinese Medicine of Gansu Province, Lanzhou 730050, Gansu Province, China 827975272@qq.com
  • About author:Xie Xing-wen☆, Doctor, Associate chief physician, Institute of Traditional Chinese Medicine of Gansu Province, Lanzhou 730050, Gansu Province, China 827975272@qq.com

PDF

919

被引次数

23

摘要：

背景：镁是可被人体吸收的常量元素，作为医用生物材料具有明显的优势。
目的：综述镁及镁合金在骨科应用中的优点、缺点及近年来国内外的研究进展。
方法：由第一作者检索2000/2011 PubMed数据及CNKI数据库有关镁离子合金在医疗领域的研究进展等方面的文献。
结果与结论：传统医用金属材料包括不锈钢、钴基合金和钛基合金存在生物相容性差、生物力学性能不匹配、需要二次手术等弊端，镁合金具有良好的生物力学相容性、可降解性能、生物安全性，并且资源丰富。可在生理电解质环境中通过腐蚀而发生降解的特性，在骨科领域展示了巨大的潜在应用前景。

关键词: 镁, 镁合金, 可吸收材料, 金属材料, 骨科

Abstract:

BACKGROUND: Magnesium ions are constant element, can be absorbed by the body and have obvious advantages as medical biomaterials.
OBJECTIVE: To summarize the advantages, disadvantages, and research progress of magnesium ions and magnesium alloys application in orthopedics in recent years.
METHODS: PubMed database and CNKI database were used to search the articles published from 2000 to 2011 on the progress of magnesium ions and magnesium alloys application in medical field.
RESULTS AND CONCLUSION: The traditional medical metal materials including stainless steel, cobalt-based alloy and titanium based alloys which have the disadvantages of poor biocompatibility, un-matched biomechanical properties and the second surgery, and other defects. Magnesium alloys have good biomechanical compatibility, biodegradable performance, bio-security and rich resource. Magnesium alloys have the characteristics of degradation through the corrosion under physiological electrolyte environment and show a great application potential in the orthopedics field.

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