中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (15): 2809-2812.doi: 10.3969/j.issn.1673-8225.2011.15.036

• 组织构建学术探讨 tissue construction academic discussion • 上一篇    下一篇

骨骼肌细胞与热休克蛋白

张晓峰1，王青涛2，李风晴3   

  1. 1河北司法警官职业学院警体教育部，河北省石家庄市  050081
    2河北大学体研部，河北省保定市  071000
    3河北传媒学院艺术体育系，河北省石家庄市  050035
  • 收稿日期:2010-09-28 修回日期:2010-11-19 出版日期:2011-04-09 发布日期:2013-11-06
  • 作者简介:张晓峰★，男，1977年生，河北省卢龙县人，汉族，2001年河北体育学院毕业，硕士，讲师，主要从事运动生理学方面的研究。 zhangxiaofeng778170@126.com

Heat shock protein in skeletal muscle cells

Zhang Xiao-feng1, Wang Qing-tao2, Li Feng-qing3   

  1. 1Department of Superintendent of the Ministry of Education, Hebei Vocational College for Correctional Police, Shijiazhuang  050081, Hebei Province, China
    2Department of Sport Education, Hebei University, Baoding  071000, Hebei Province, China
    3Department of Physical Education, Hebei Institute of Communication, Shijiazhuang  050035, Heibei Province, China
  • Received:2010-09-28 Revised:2010-11-19 Online:2011-04-09 Published:2013-11-06
  • About author:Zhang Xiao-feng★, Master, Lecturer, Department of Superintendent of the Ministry of Education, Hebei Vocational College for Correctional Police, Shijiazhuang 050081, Hebei Province, China

PDF

499

摘要：

背景：骨骼肌含有多种热休克蛋白，可能具有重要的生理功能。
目的：综述骨骼肌热休克蛋白的特性，以及骨骼肌热休克蛋白在生理及病理情况下表达的意义。
方法：以“热休克蛋白，骨骼肌，运动，缺血再灌注”为中文检索词，以“heat shock proteins, skeletal muscle, exercise, ischemia-reperfusion”为英文检索词，应用计算机检索Pubmed数据库和中文期刊全文数据库2010-06前发表的相关文章。纳入与骨骼肌细胞热休克蛋白研究相关的文献，排除重复性研究。
结果与结论：共检索到197篇文献，排除无关重复的文献，保留35篇文献进行综述。目前研究证实骨骼肌含有多种热休克蛋白，主要有小热休克蛋白，热休克蛋白70，热休克蛋白60和热休克蛋白90等。热休克蛋白作为应激的指标，可以反映运动时细胞内发生的变化，对监控过度训练有重要意义。同时热休克蛋白在过度训练或肌肉损伤时对保持肌肉功能起重要作用。

关键词: 热休克蛋白, 骨骼肌, 运动, 缺血再灌注, 组织工程

Abstract:

BACKGROUND: There are many kinds of heat shock proteins in skeletal muscle, and they have important physiologic functions.
OBJECTIVE: To review the features of heat shock proteins, and to discuss the significance of heat shock proteins under both physiological and physiologic conditions.
METHODS: Databases of PubMed and CNKI were searched by computer using key words of “heat shock proteins, skeletal muscles, exercise, ischemia-reperfusion” both in English and Chinese. Literatures addressing heat shock proteins in skeletal muscles cells were included, and the repetitive researches were excluded. 
RESULTS AND CONCLUSION: A total of 197 documents were retrieved, and 35 articles were retained after depleting unrelated and repetitive ones. To date, skeletal muscles contain a variety of heat shock proteins, mainly comprise small heat shock protein, heat shock protein 70, heat shock protein 60 and heat shock protein 90. Heat shock proteins play an important role in reflecting intra-cellular changes during sports and monitoring over training. In addition, heat shock proteins are important in maintaining muscle function after over training or muscle injury.

中图分类号: