中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (13): 2390-2393.doi: 10.3969/j.issn.1673-8225.2011.13.026

• 数字化骨科 digital orthopedics • 上一篇    下一篇

基于心率的主动脉血泵流量控制

谷凯云，高  斌，常  宇   

  1. 北京工业大学生命科学与生物工程学院，北京市  100124
  • 收稿日期:2010-12-06 修回日期:2011-01-18 出版日期:2011-03-26 发布日期:2013-10-23
  • 通讯作者: 常宇，博士，副教授，北京工业大学生命科学与生物工程学院，北京市100124 changyu@bjut. edu.cn
  • 作者简介:谷凯云★，女，1986年生，北京市人，汉族，北京工业大学在读硕士，主要从事生物医学工程研究。 gukaiyun@ emails.bjut.edu. cn
  • 基金资助:

    10北京工业大学人才强教深化计划-创新团队项目(31500054R5001)“心脑血管病手术规划”；10人才强教深化计划-211工程-北京工业大学高层次人才培养项目(01500054R8001)“新型医疗装备与技术-心脑血管疾病的信息检测技术研究”；国家自然科学基金(11072012)“心室辅助中血流脉动量对主动脉影响的研究”。

Flow control of intra aorta pump based on heart rate

Gu Kai-yun, Gao Bin, Chang Yu   

  1. School of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China
  • Received:2010-12-06 Revised:2011-01-18 Online:2011-03-26 Published:2013-10-23
  • Contact: Chang Yu, Doctor, Associate professor, School of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China changyu@bjut.edu. cn
  • About author:Gu Kai-yun★, Studying for master’s degree, School of Life Science and Bioengineering, Beijing University of Technology, Beijing 100124, China gukaiyun@emails. bjut.edu.cn
  • Supported by:

    the Funding Project for Academic Human Resources Development in Beijing University of Technology- Invonotion Team, No. 31500054R5001*; Funding Project for Academic Human Resources Development-211 Project-Cultivation of High-Level Talents in Beijing University of Technology, No. 01500054R8001*; the National Natural Science Foundation of China, No. 11072012*

PDF

633

被引次数

12

摘要：

背景：随着人工心脏研究和应用的不断发展，在装置的性能上，人们希望它能符合自然心脏的生理机制，满足受者的生理需求。
目的：针对主动脉血泵的控制，提出了基于心率的血泵流量控制算法。
方法：通过分析心率与流量之间的关系，建立了心率与流量的关系模型，并根据人体心率流量关系验证血泵流量模型的准确性。运用PID控制算法对血泵流量进行控制。
结果与结论：仿真结果表明血泵可以实现快速稳定的输出。当心率为75次/min时，流量能达到5.01 L/min；在50~120次/min心率范围内，流量会随着心率的提高而增大；当心率大小于50次/min或于120次/min时，血泵工作在恒流量状态下。通过PID控制，可使流量在0.1 s内跟踪上参考流量。基于心率的血泵流量模型能反映人体血流量需求，通过控制血泵可实现满足人体需求的流量输出。

关键词: 血泵, 心率, 流量, PID控制, 人工心脏

Abstract:

BACKGROUND: With the development of the research and application of artificial heart, people hope that it can accord with physiological mechanism of natural heart and meet demand of human body in device performance.
OBJECTIVE: For the control of intra-aorta pump, this paper proposed the flow control algorithm based on heart rate.
METHODS: Utilizing the PID control algorithm to maintain the output flow satisfy the physical needs of patients. Simulation results show the accuracy of the algorithm to achieve fast and stable flow blood pump output.
RESULTS AND CONCLUSION: When the heart rate was of 75 times per minute, blood pump flow rate could reach 5.01 L/min; blood pump flow gradually increased with the heart rate when the heart rate was in the range from 50 to 120 times per minute; blood pump kept constant flow state when the heart rate less than 50 times per minute or more than 120 times per minute. Through PID control, the actual flow rate tracks the reference one within 0.1 s. The blood pump flow model based on heart rate can reflect the needs of human blood flow. The control algorithm can achieve stable flow blood pump output, to keep pace human needs of patients.

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