中国组织工程研究 ›› 2010, Vol. 14 ›› Issue (4): 752-756.doi: 10.3969/j.issn.1673-8225.2010.04.043

• 人工假体 artificial prosthesis • 上一篇    下一篇

经椎弓根钉板内固定治疗上颈椎疾患的个性化设计及临床应用

贾卫斗,白桂有,杨  飞,杨博贵,郑铁钢,许英杰,云得才,孙  华   

  1. 解放军第二五一医院骨科,河北省张家口市  075000
  • 出版日期:2010-01-22 发布日期:2010-01-22
  • 作者简介:贾卫斗,男,1950年生,山西省临汾市人,汉族,1976年河北医科大学医学系毕业,主任医师,教授,硕士生导师,主要从事脊柱外科的基础及临床研究。

Individual protocol and clinical application of pedicle screw and plate internal fixation for the treatment of upper cervical disorders

Jia Wei-dou, Bai Gui-you, Yang Fei, Yang Bo-gui, Zheng Tie-gang, Xu Ying-jie, Yun De-cai, Sun Hua   

  1. Department of Orthopaedics, the 251 Hospital of Chinese PLA, Zhangjiakou   075000, Hebei Province, China
  • Online:2010-01-22 Published:2010-01-22
  • About author:Jia Wei-dou, Chief physician, Professor, Master’s supervisor, Department of Orthopaedics, the 251 Hospital of Chinese PLA, Zhangjiakou 075000, Hebei Province, China Jwdzr251@sina.com

摘要:

背景:上颈椎疾患从后路行椎弓根固定在国内个别大型医院虽已相继开展,但该手术仍为颈椎外科高难度手术。为了将手术风险降至最低,作者设计了一套个体化手术方案,并结合自行研制的椎弓根定位导向器行术中精确定位置钉,经检索相关数据库在国内未见报道。
目的:提高内固定置钉的一次成功率及植入体的生物力学效应,利用辅助检查资料为寰枢椎椎弓根螺钉的置钉制定简单、实用的个性化方案。
方法:选择2002-01/2006-09解放军第二五一医院骨科患者31例。术中采用自制的寰枢椎定位导向器,根据寰枢椎椎弓根X射线-CT个体化测量的结果,确定进钉点、入钉的角度,选择直径及长度合适的椎弓根螺钉置入。寰椎椎弓根进钉点:左侧(19.93±  1.32) mm,右侧(19.16±1.30) mm,寰椎椎弓根向内侧进钉角度:左侧(23.72±2.09)°,右侧(23.35±1.91)°,寰椎向头侧进钉角度(9.00±1.20)°。枢椎椎弓根进钉点:左侧(13.14±0.82) mm,右侧(13.85±0.79) mm。 枢椎椎弓根向内侧进钉角度:左侧(24.52±1.26)°,右侧(20.42±1.42)°,枢椎向头侧进钉角度(25.00±3.00)°。
结果与结论:①31例患者置入124枚椎弓根螺钉,1次置钉成功122枚螺钉,正确率为98.39%,有2枚因内倾角偏差不够,穿破椎弓根的外侧骨皮质而改为2次定位。②2例术后出现枕大神经痛,经对症治疗1个月后痊愈,2例螺钉穿破寰椎左侧椎弓根外侧壁,未发现脊髓、椎动脉损伤。③所有患者X射线平片显示寰椎完全复位,枢椎齿状突骨折处对位良好。CT片示螺钉与椎动脉的脊髓位置关系良好。④平均随访10.5个月,均获得骨性融合,未发现钉板断裂材料反应。无炎症、排异等宿主反应。⑤按JOA评分标准,优16例,良12例,可2例,差1例,优良率90%。提示从生物力学角度实施植入体置入,可提高寰枢椎椎弓根螺钉的置入成功率。

关键词: 寰枢椎, 椎弓根, X射线-CT个性化, 测量, 固定

Abstract:

BACKGROUND: The treatment of upper cervical spine disorders through a posterior pedicle fixation approach have been carried out in some domestic large hospitals, but this surgery is still considered as a difficulty of cervical spine surgery. In order to minimize the risk of surgery, the authors designed a program of individual operations, and combined with self-developed pedicle locating and directing speculum to determine precise intraoperative position of pedicle screws, and no report is found by searching related database in China. 
OBJECTIVE: To improve the one-time success rate of internal fixation screws, to investigate the biomechanical effect of the implant, to formulate a simple, practical, individual protocol for atlantoaxial pedicle screw-plate system based on related data.
METHODS: A total of 31 patients were recruited from Department of Orthopaedics in the 251 Hospital of Chinese PLA, between January 2002 and September 2006. Under the guidance of self-made atlantoaxial locating and directing speculum, the entrance point and angle for screw insertion, as well as screw diameter and length were determined according to the results of X-ray and CT measurement. Atlas pedicle screw was inserted at left (19.93±1.32) mm, and right (19.16±1.3) mm; Atlas pedicle screw insertion angle to inside was left (23.72±2.09)°, and right (23.35±1.91)°; Atlas pedicle screw insertion angle to side of head was (9.00±1.20)°. Axis pedicle screw was inserted at left (13.14±0.82) mm, and right (13.85±0.79) mm; Axis pedicle screw insertion angle to inside was left (24.52±1.26)°, and right (20.42±1.42)°; Axis pedicle screw insertion angle to side of head was (25.00±3.00)°.
RESULTS AND CONCLUSION:  ①Totally 124 pedicle screws were implanted into 31 patients, and 122 screws were of one-time success. The precision rate was 98.39%. Two screws were secondly inserted because of cutting lateral cortical bone of pedicle for deviation of inward angle. ②Occipital neuralgia was found in 2 cases postoperatively and cured after one month of treatment; screws penetrated atlas left vertebral lateral wall in 2 cases, no spinal or vertebral artery injury was found. ③Radiographs showed that atlas was completely reduced in all patients, and apposition of dentoid process of axis fracture was good. CT films showed the screws a good location to the vertebrarterial spinal cord. ④The follow-up visit was averaged of 10.5 months. Bony fusion was found in all patients. No screw-plate breakage was found. No inflammatory or rejection reactions occurred. ⑤By JOA scale, there were 16 cases of excellent, 12 cases of good, 2 cases of fine, and 1 case of poor. The excellent and good rate was 90%. It is suggested that the success rate of atlantoaxial pedicle screw-plate implantation can be improved through a biomechanical angle.

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