中国组织工程研究 ›› 2018, Vol. 22 ›› Issue (15): 2396-2406.doi: 10.3969/j.issn.2095-4344.0760
• 骨与关节综述 bone and joint review • 上一篇 下一篇
冯 硕,查国春,郭开今,陈向阳
出版日期:
2018-05-28
发布日期:
2018-05-28
通讯作者:
陈向阳,博士,主任医师,徐州医科大学附属医院骨科,江苏省徐州市 221000
作者简介:
冯硕,男,1993年生,安徽省宿州市人,汉族,徐州医科大学在读硕士,目前从事骨关节及脊柱外科等方面的研究。
基金资助:
江苏省青年医学人才项目(QNRC2016800);徐州市科技计划项目(KC16SL111);江苏省卫计委面上项目(H2017081);江苏省级社会发展重点项目(BE2015627)
Feng Shuo, Zha Guo-chun, Guo Kai-jin, Chen Xiang-yang
Online:
2018-05-28
Published:
2018-05-28
Contact:
Chen Xiang-yang, M.D., Chief physician, Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu Province, China
About author:
Feng Shuo, Master candidate, Department of Orthopedics, Affiliated Hospital of Xuzhou Medical University, Xuzhou 221000, Jiangsu Province, China
Supported by:
the Youth Medical Talent Project of Jiangsu Province, No. QNRC2016800; the Science and Technology Project of Xuzhou City, No. KC16SL111; the General Program of Health Planning Commission of Jiangsu Province, No. H2017081; the Key Project for Social Development in Jiangsu Province, No. BE2015627
摘要:
文章快速阅读:
中图分类号:
冯 硕,查国春,郭开今,陈向阳. 髋关节股骨侧翻修:原因、分型及不同修复技术的应用原则[J]. 中国组织工程研究, 2018, 22(15): 2396-2406.
Feng Shuo, Zha Guo-chun, Guo Kai-jin, Chen Xiang-yang . Femoral revision of the hip: reason, type and different techniques[J]. Chinese Journal of Tissue Engineering Research, 2018, 22(15): 2396-2406.
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1.1 资料来源
深层感染(subfascial extension of infection)是目前是翻修的第3个最常见的原因,其发生率在0.3%-2.2%,特别是假体周围感染对于关节科医生来说是一个非常严峻挑战。细菌侵入髋关节后,移行至假体表面,黏附增殖形成一种膜,被称细菌生物被膜,细菌生物被膜的形成,机体的炎症细胞无法对其吞噬清除,躲藏在多糖基质内的细菌会释放各种炎性因子及酶类,造成局部的组织坏死和骨溶解,导致假体松动。不幸的是生物被膜内的细菌会产生耐药,且耐药机制尚不清楚,如何有效治疗仍是一大难点。目前,除了使用抗生素以外,有学者也将目光转到改进制造假体的材料上。 中国组织工程研究杂志出版内容重点:人工关节;骨植入物;脊柱;骨折;内固定;数字化骨科;组织工程
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