中国组织工程研究

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

赝复体钛网同期植入修复上颌骨切除后眶面部缺损

温立婷,乔  莉,陈福权,陈晓栋,石照辉   


  1. 解放军第四军医大学西京医院耳鼻咽喉头颈外科,陕西省西安市  710032
  • 收稿日期:2013-02-04 修回日期:2013-03-20 出版日期:2013-05-21 发布日期:2013-05-21
  • 通讯作者: 石照辉,博士,主治医师,解放军第四军医大学西京医院耳鼻咽喉头颈外科,陕西省西安市 710032 zhaohuishi@139.com
  • 作者简介:温立婷,女,1981年生,山东省阿县人,汉族,2004年大学毕业,医师,主要从事耳鼻喉科基础疾病诊治的研究。 zhadjun@fmmu.edu.cn

Prosthetic titanium mesh simultaneous implantation for the treatment of orbital facial defects after maxillectomy

Wen Li-ting, Qiao Li, Chen Fu-quan, Chen Xiao-dong, Shi Zhao-hui   

  1. Department of Otolaryngology and Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University of PLA, Xi’an  710032, Shaanxi Province, China
  • Received:2013-02-04 Revised:2013-03-20 Online:2013-05-21 Published:2013-05-21
  • Contact: Shi Zhao-hui, M.D., Attending physician, Department of Otolaryngology and Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University of PLA, Xi’an 710032, Shaanxi Province, China
  • About author:Wen Li-ting, Physician, Department of Otolaryngology and Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University of PLA, Xi’an 710032, Shaanxi Province, China zhadjun@fmmu.edu.cn

摘要:

背景:上颌骨创伤或肿瘤切除后可发生面部骨缺损,严重影响患者的外观和生活质量,早期修复对患者意义重大。
目的:探讨上颌骨切除后同期钛网与赝复体植入修复眶面部缺损以及长期疗效。
方法:选取2009年6月至2013年1月在解放军第四军医大学西京医院耳鼻咽喉头颈外科接受上颌骨切除的患者,治疗中同期植入钛网修复眶底以及上颌窦前壁骨质缺损的上颌窦恶性肿瘤患者共21例,其中上颌骨部分切除4例,上颌骨全切11例,上颌骨扩大切除6例,随访观察钛网在上颌骨切除后遗留的面中部及眶区缺损的修复效果。
结果与结论:所有患者同期钛网植入后创口均一期愈合,颜面部轮廓对称,眼球功能正常,患者对颜面部外观基本满意,联合赝复体后能进软食,语言清晰,2例患者在修复后辅助放疗,出现钛网植入体部分外露,经临近皮瓣转移修复后痊愈。结果显示,钛网可以对上颌骨缺损患者进行面部修复重建,对恢复面部形态、防止复视发生、后期功能修复以及提高患者生存质量均有明确疗效。

关键词: 生物材料, 生物材料学术探讨, 钛网, 钛板, 微型钛板, 赝复体, 植入物, 上颌骨切除, 骨重建, 面部缺损, 修复重建, 上颌窦, 鼻窦肿瘤, 骨折

Abstract:

BACKGROUND: Facial bone defects may occur after maxillary trauma or tumor resection, which may influence the appearance and the life quality of the patients, so the early repairing has great significance to the patients.   
OBJECTIVE: To investigate the long-term effect of prosthetic titanium mesh simultaneous implantation for the treatment of orbital facial defect after maxillectomy.
METHODS: Twenty-one maxillary sinus malignancy patients received maxillectomy, and the maxillary sinus malignancy patients treated with titanium mesh simultaneous implantation to repair orbital floor and anterior maxillary sinus wall bone defects in the Department of Otolaryngology and Head and Neck Surgery, Xijing Hospital, the Fourth Military Medical University of PLA from June 2009 to January 2013 were selected. Among the 21 patients, four cases received partial resection of maxilla, 11 cases received maxillectomy, and six cases received maxillary extended resection. The effect of titanium mesh on the repair of midface and orbital defects after maxillectomy was observed during follow-up.
RESULTS AND CONCLUSION: All the patients obtained one stage healing after titanium mesh simultaneous implantation with symmetrical facial contour and normal eyeball function, and the patients were basically satisfied with the facial appearance. All the patients could eat soft diet and had clear language after treated with prosthetic titanium mesh implantation; two cases had partial titanium mesh implant exposure after adjuvant radiotherapy, and healed after nearby flap transplantation. The results show that titanium mesh can be used for facial repair and reconstruction in the maxillary defect patients, and has significant effect in restoring facial appearance, preventing diplopia occurrence, repairing late function and improving life quality.

Key words: biomaterials, biomaterial academic discussion, titanium mesh, titanium plate, mini-titanium plate, prosthesis, implants, maxillectomy, bone reconstruction, facial defects, repair and reconstruction, maxillary sinus, sinus tumor, fracture

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