[1] Suh JK, Matthew HW. Application of chitosan-based polysaccharide biomaterials in cartilage tissue engineering: a review. Biomaterials. 2000;21(24):2589-2598.
[2] 范宏斌.体内诱导骨髓基质干细胞修复兔关节软骨缺损及其相关研究[D].西安:第四军医大学,2006:15-22.
[3] Kinner B, Capito RM, Spector M. Regeneration of articular cartilage. Adv Biochem Eng Biotechnol. 2005;94:91-123.
[4] Hunziker EB. Articular cartilage repair: basic science and clinical progress. A review of the current status and prospects. Osteoarthritis Cartilage. 2002;10(6):432-463.
[5] Chung C, Burdick JA. Influence of three-dimensional hyaluronic acid microenvironments on mesenchymal stem cell chondrogenesis. Tissue Eng Part A. 2009;15(2): 243-254.
[6] Nesic D, Whiteside R, Brittberg M,et al. Cartilage tissue engineering for degenerative joint disease. Adv Drug Deliv Rev. 2006;58(2):300-322.
[7] 杨强,彭江,卢世璧,等.组织工程骨软骨复合体修复犬膝关节负重区骨软骨缺损的实验研究[J].中华骨科杂志,2009,29(5): 480-486.
[8] 吴追乐,李民,刘献祥,等.BMSCs体外分离培养的实验研究[J].福建中医学院学报,2008,18(4):24-27.
[9] 蒿俊行,郝剑,朴哲,等.工程软骨支架的临床应用研究进展[J].国际生物医学工程杂志,2011,34(6):380-382.
[10] 韦益毅.不同生物材料复合支架对关节软骨缺损的修复评价[J].中国组织工程研究与临床康复,2011,15(25):4723-4725.
[11] Zhu L, Wu Y, Jiang H,et al. Engineered cartilage with internal porous high-density polyethylene support from bone marrow stromal cells: A preliminary study in nude mice. Br J Oral Maxillofac Surg. 2010 ;48(6):462-465.
[12] 吴俊,薛珂,刘凯,等.软骨细胞与骨髓间充质干细胞隔离共培养构建组织工程化软骨[J].苏州大学学报:医学版,2012,32(2): 202-206.
[13] 雷鸣,刘世清,刘宇兰,等.藻酸钠微球中骨髓间充质干细胞向软骨细胞的定向分化[J].中国组织工程研究与临床康复,2008, 12(19): 3659-3662.
[14] 谭文成,林宏生,张嘉晴,等.动物源性骨软骨支架修复兔膝关节复合缺损[J].中国骨科临床与基础研究杂志,2011,3(1): 51-59.
[15] 李明波.透骨消痛颗粒诱导骨髓基质细胞向软骨细胞分化的实验研究[D].福建:福建中医学院,2009:6-7.
[16] Cao L, Yang F, Liu G,et al.The promotion of cartilage defect repair using adenovirus mediated Sox9 gene transfer of rabbit bone marrow mesenchymal stem cells.Biomaterials. 2011; 32(16):3910-3920.
[17] 曹慧慧,王昌留.Sox基因家族特点及其功能[J].鲁东大学学报:自然科学版,2011,27(1):58-63.
[18] Smits P, Li P, Mandel J,et al.The transcription factors L-Sox5 and Sox6 are essential for cartilage formation. Dev Cell. 2001; 1(2):277-290.
[19] Lefebvre V, Smits P. Transcriptional control of chondrocyte fate and differentiation. Birth Defects Res C Embryo Today. 2005;75(3):200-212.
[20] 钱晓伟,谭湘陵,张贤,等.Sox6基因和Col2a1在大鼠bMSCs体外成软骨分化中表达及其意义[J].江苏医药,2012,38(19): 2240- 2243.
[21] 张佼佼,王冬青,王志强,等.组织工程软骨支架材料的应用选择[J].中国组织工程研究与临床康复,2011,15(29):5467-5470.
[22] 王国海.组织工程方法修复关节骨软骨缺损的实验研究[D].广东:中山大学,2007:1-4.
[23] 吴军成,霍然,吕仁荣.软骨组织工程中支架材料的文献回顾[J].中国组织工程研究,2012,16(3):522-526.
[24] 初殿伟,王玮,王文良.骨软骨组织工程支架的研究现状[J].武警医学院学报,2009,18(3):240-244.
[25] Yates KE, Allemann F, Glowacki J. Phenotypic analysis of bovine chondrocytes cultured in 3D collagen sponges: effect of serum substitutes. Cell Tissue Bank. 2005;6(1):45-54.
[26] Lahiji A, Sohrabi A, Hungerford DS,et al. Chitosan supports the expression of extracellular matrix proteins in human osteoblasts and chondrocytes. J Biomed Mater Res. 2000; 51(4):586-595.
[27] 夏万尧,曹谊林,商庆新,等.壳聚糖作为组织工程软骨支架的实验研究[J].中华显微外科杂志,2002,25(1):34-37.
[28] Montembault A, Tahiri K, Korwin-Zmijowska C,et al. A material decoy of biological media based on chitosan physical hydrogels: application to cartilage tissue engineering. Biochimie. 2006 ;88(5):551-564.
[29] 刘清宇,王富友,杨柳.关节软骨组织工程支架的研究进展[J].中国修复重建外科杂志,2012,26(10):1247-1250.
[30] Heymer A, Bradica G, Eulert J,et al. Multiphasic collagen fibre-PLA composites seeded with human mesenchymal stem cells for osteochondral defect repair: an in vitro study. J Tissue Eng Regen Med. 2009;3(5):389-397.
[31] El Sayed K, Marzahn U, John T,et al. PGA-associated heterotopic chondrocyte cocultures: implications of nasoseptal and auricular chondrocytes in articular cartilage repair. J Tissue Eng Regen Med. 2013;7(1):61-72.
[32] 刘方红,张秋芳.骨髓基质干细胞复合PLGA支架修复兔关节软骨缺损[J].中国老年保健医学,2011,9(4):5-6.
[33] 李炜.组织工程骨软骨修复材料的研究进展[J].健康必读,2012, 11(5):518-519.
[34] 张新.不同材料构建组织工程软骨及支架的应用[J].中国组织工程研究,2012,16(8):1491-1495.
[35] 杨红涛.聚己酸内酯壳聚糖共混材料用于软骨组织工程支架的研究[D].武汉:华中科技大学,2009:1-52.
[36] 周晓中,张文智,吕维佳,等.多聚乙醇酸-羟基磷灰石复合体为支架的骨髓基质细胞修复兔关节软骨缺损[J].中华创伤杂志, 2005,21(8):617-620.
[37] 张永红,许钰,林汲,等.羟基丁酸-羟基辛酸共聚体/脱细胞软骨基质支架的细胞黏附性[J].中国组织工程研究与临床康复,2010, 14(25):4585-4588.
[38] 郭霄飞,张永红,杜美丽,等.羟基丁酸与羟基辛酸共聚物一体化骨软骨组织工程支架的制备及性能[J].中国组织工程研究,2012, 16(16):2865-2868.
[39] 张金超,刘丹丹,周国强,等.纳米材料在组织工程中的应用[J].化学进展,2010,22(11):2232-2237.
[40] 李劼若,查振刚,姚平,等.纳米羟基磷灰石壳聚糖支架与诱导骨髓间充质干细胞体外构建软骨支架复合体[J].中国组织工程研究与临床康复,2009,13(3):411-416.
[41] Meng ZX, Xu XX, Zheng W,et al. Preparation and characterization of electrospun PLGA/gelatin nanofibers as a potential drug delivery system. Colloids Surf B Biointerfaces. 2011;84(1):97-102.
[42] 朱凌云,王彦平,石宗利,等.纳米羟基磷灰石/聚磷酸钙纤维/聚乳酸骨组织工程复合支架的特性[J].中国组织工程研究,2012, 16(3):431-433.
[43] 韦宋谱,丁道芳,王学宗,等.骨髓间充质干细胞的培养及向软骨细胞诱导的方法学研究进展[J].中国矫形外科杂志,2012,20(11): 1017-1019.
[44] 刘志强,程红斌,刘建国,等.骨髓间充质干细胞在关节软骨损伤中的应用[J].中国实验诊断学,2012,16(2):373-375.
[45] Wang MK, Sun HQ, Xiang YC,et al. Different roles of TGF-β in the multi-lineage differentiation of stem cells.World J Stem Cells. 2012;4(5):28-34.
[46] Narcisi R, Signorile L, Verhaar JA,et al. TGFβ inhibition during expansion phase increases the chondrogenic re-differentiation capacity of human articular chondrocytes. Osteoarthritis Cartilage. 2012;20(10):1152-1160.
[47] Barry F, Boynton RE, Liu B,et al. Chondrogenic differentiation of mesenchymal stem cells from bone marrow: differentiation-dependent gene expression of matrix components. Exp Cell Res. 2001;268(2):189-200.
[48] You M, Peng G, Li J,et al. Chondrogenic differentiation of human bone marrow mesenchymal stem cells on polyhydroxyalkanoate (PHA) scaffolds coated with PHA granule binding protein PhaP fused with RGD peptide. Biomaterials. 2011;32(9):2305-2313.
[49] 杨亚冬,张文元,房国坚.负载TGF-β1微球的壳聚糖丝素支架复合骨髓间充质干细胞修复兔关节软骨缺损的实验研究[J].医学研究杂志,2011,40(6):70-75.
[50] Spagnoli A, O'Rear L, Chandler RL,et al. TGF-beta signaling is essential for joint morphogenesis. J Cell Biol. 2007 ;177(6): 1105-1117.
[51] Qureshi HY, Sylvester J, El Mabrouk M,et al. TGF-beta-induced expression of tissue inhibitor of metalloproteinases-3 gene in chondrocytes is mediated by extracellular signal-regulated kinase pathway and Sp1 transcription factor. J Cell Physiol. 2005;203(2):345-352.
[52] 郑东,刘国辉,杨述华,等.转化生长因子-β3融合蛋白促进骨髓基质干细胞向软骨分化的研究[J].中华实验外科杂志,2010,27(1): 104-107.
[53] Grimaud E, Heymann D, Rédini F. Recent advances in TGF-beta effects on chondrocyte metabolism. Potential therapeutic roles of TGF-beta in cartilage disorders. Cytokine Growth Factor Rev. 2002 ;13(3):241-257.
[54] Mueller MB, Fischer M, Zellner J,et al. Hypertrophy in mesenchymal stem cell chondrogenesis: effect of TGF-beta isoforms and chondrogenic conditioning. Cells Tissues Organs. 2010;192(3):158-166.
[55] Sekiya I, Colter DC, Prockop DJ. BMP-6 enhances chondrogenesis in a subpopulation of human marrow stromal cells. Biochem Biophys Res Commun. 2001;284(2):411-418.
[56] Indrawattana N, Chen G, Tadokoro M,et al. Growth factor combination for chondrogenic induction from human mesenchymal stem cell. Biochem Biophys Res Commun. 2004;320(3):914-919.
[57] 邓娟.骨髓基质干细胞定向分化为软骨细胞的研究进展[J].海南医学,2012,23(14):126-129.
[58] Longobardi L, O'Rear L, Aakula S,et al. Effect of IGF-I in the chondrogenesis of bone marrow mesenchymal stem cells in the presence or absence of TGF-beta signaling. J Bone Miner Res. 2006;21(4):626-636.
[59] 刘瑾春,刘霞,曹谊林.体外诱导BMSCs向软骨分化的方法研究进展[J].中国修复重建外科杂志,2011,25(5):618-623.
[60] Solchaga LA, Penick K, Porter JD,et al. FGF-2 enhances the mitotic and chondrogenic potentials of human adult bone marrow-derived mesenchymal stem cells. J Cell Physiol. 2005;203(2):398-409.
[61] Cui X, Breitenkamp K, Lotz M,et al. Synergistic action of fibroblast growth factor-2 and transforming growth factor-beta1 enhances bioprinted human neocartilage formation. Biotechnol Bioeng. 2012;109(9):2357-2368.
[62] Wang WG, Lou SQ, Ju XD,et al. In vitro chondrogenesis of human bone marrow-derived mesenchymal progenitor cells in monolayer culture: activation by transfection with TGF-beta2. Tissue Cell. 2003;35(1):69-77.
[63] 程越,田京.纳米支架与关节软骨重建[J].中国组织工程研究, 2012, 16(12):2265-2269.
[64] Pape D, Filardo G, Kon E,et al. Disease-specific clinical problems associated with the subchondral bone. Knee Surg Sports Traumatol Arthrosc. 2010;18(4):448-462. |