中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (38): 7185-7192.doi: 10.3969/j.issn.2095-4344.2012.38.030

• 生物材料学术探讨 biomaterial academic discussion • 上一篇    下一篇

聚乙丙交酯新型埋线材料与羊肠线的临床应用比较

刘慧敏   

  1. 青海大学附属医院康复科，青海省西宁市 810001
  • 收稿日期:2012-04-25 修回日期:2012-08-30 出版日期:2012-09-16 发布日期:2012-09-16
  • 作者简介:刘慧敏，女，1971年生，青海省西宁市人，汉族，2008年青海医学院毕业，主治医师，主要从事针灸康复研究。 404113730@qq.com

Clinical comparison of poly-lactic-co-glycolic acid new catgut embedding material and catgut

Liu Hui-min   

  1. Department of Rehabilitation, Affiliated Hospital of Qinghai University, Xining 810001, Qinghai Province, China
  • Received:2012-04-25 Revised:2012-08-30 Online:2012-09-16 Published:2012-09-16
  • About author:Liu Hui-min, Attending physician, Department of Rehabilitation, Affiliated Hospital of Qinghai University, Xining 810001, Qinghai Province, China 404113730@qq.com

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491

被引次数

21

摘要：

背景：埋线技术是利用微创器械将生物可降解材料的线体埋到人体特定的部位或穴位，通过生物可降解线体在经络穴位内形成长期刺激，调整经络脏腑功能，进行疾病治疗的一种技术。
目的：比较聚乙丙交酯新型埋线材料及羊肠线用于临床的实际表现，探讨聚乙丙交酯新型埋线材料的应用特点。
方法：选取需要埋线治疗的150例患者，随机分为观察组与对照组，每组75例患者。其中观察组包括脊柱疾病患者32例，癫痫患者22例，神经性耳鸣患者21例，采用聚乙丙交酯新型埋线材料进行治疗；对照组包括脊柱疾病患者29例，癫痫患者23例，神经性耳鸣患者23例，采用羊肠线材料进行治疗。对两组的疗效及红外热像进行比较及统计学分析，观察两种埋线材料是否存在疗效及局部反应的显著差异。
结果与结论：观察组脊柱相关性疾病患者有效率为87.5%，癫痫患者有效率为81.8%，神经性耳鸣患者有效率为 90.5%；对照组的脊柱相关性疾病患者有效率为79.3%，癫痫患者有效率为69.6%，神经性耳鸣患者有效率为78.3%，各病种两种埋线材料治疗有效率经比较分析，差异无显著性意义。植入聚乙丙交酯新型埋线材料的观察组局部体温恢复正常明显较植入羊肠线的对照组更快，组间比较差异有显著性意义(P < 0.05)。聚乙丙交酯新型埋线材料用于穴位埋线治疗，与传统羊肠线相比较疗效并无显著优势，但聚乙丙交酯新型埋线材料具有不易过敏，局部排异反应小，感染风险较低等优势，可提升整体治疗疗效。

关键词: 聚乙丙交酯, 羊肠线, 埋线材料, 脊柱疾病, 癫痫, 神经性耳鸣, 排斥反应, 感染, 过敏反应, 中医康复, 生物材料

Abstract:

BACKGROUND: The catgut embedding technology can embed the line body of biodegradable materials to the specific body parts or points through minimally invasive devices, and it can adjust the meridians and organs function for disease treatment through biodegradable line body formed long-term stimulus in the meridian points.
OBJECTIVE: To compare the clinical effect of poly-lactic-co-glycolic acid new catgut embedding material and catgut and to investigate the application characteristics of poly-lactic-co-glycolic acid new catgut embedding material.
METHODS: 150 patients treated with embedding was selected and divided into observation group and control group, 75 patients in each group. In the observation group, there were 32 patients with spinal diseases, 22 patients with epilepsy and 21 patients with nervous tinnitus, and all the patients were treated with poly-lactic-co-glycolic acid new catgut embedding material; in the control group, there were 20 patients with spinal diseases, 23 patients with epilepsy and 23 patients with nervous tinnitus, and all the patients were treated with catgut. The effect and the infrared thermography of the two materials were compared and statistically analyzed to observe whether there was significant difference of the efficacy and local reactions between two catgut embedding materials.
RESULTS AND CONCLUSION: The effective rate for the spinal disease patients was 87.50% in observation group, 81.82% for epilepsy patients and 90.48% for nervous tinnitus patients; in the control group, the effective rate for the spinal disease patients was 79.31%, 69.57% for epilepsy patients and 78.26% for nervous tinnitus patients; there was no significant difference of the effective rate for different diseases between two embedding materials. For the partialbody temperature, the time to return to normal in the observation group was shorter than that in the control group, and there was significant difference between two groups (P < 0.05). For the effect on the acupoint catgut embedding treatment, there were no significant advantages of poly-lactic-co-glycolic acid new catgut embedding material when compared with catgut, but the poly-lactic-co-glycolic acid new catgut embedding material has the advantages of not easy to allergy, lower partial rejection and lower infection risk, which can help to improve the overall treatment efficacy, so the poly-lactic-co-glycolic acid new catgut embedding material is worthy for the clinical application.

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