中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (9): 1661-1670.doi: 10.3969/j.issn.1673-8225.2012.09.033

• 骨与关节综述 bone and joint review • 上一篇    下一篇

膝关节置换后应用药物预防血栓形成的对比研究与国际分析★

范少地，王晓坤，白  峰，刘  剑，于  杰，陈戎波，周凤金，胡万华   

  1. 解放军第451医院骨科，陕西省西安市  710054
  • 收稿日期:2012-01-15 修回日期:2012-02-14 出版日期:2012-02-26 发布日期:2012-02-26
  • 作者简介:范少地★，男，1966年生，陕西省西安市人，汉族，1999年第三军医大学毕业，硕士，主任医师，主要从事关节外科方面的研究。Fansd666@163.com

The comparative research and international analysis of the application of anticoagulant to prevent thrombosis after knee replacement surgery  

Fan Shao-di, Wang Xiao-kun, Bai Feng, Liu Jian, Yu Jie, Chen Rong-bo, Zhou Feng-jin, Hu Wan-hua   

  1. Department of Orthopaedics, the 451 Hospital of Chinese PLA, Xi’an  710054, Shaanxi Province, China
  • Received:2012-01-15 Revised:2012-02-14 Online:2012-02-26 Published:2012-02-26
  • About author:Fan Shao-di★, Master, Chief physician, Department of Orthopaedics, the 451 Hospital of Chinese PLA, Xi’an 710054, Shaanxi Province, China Fansd666@163.com

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摘要：

背景：应用抗凝药物预防膝关节置换后血栓形成已经成为学科界的共识。
目的：利用SCI数据库文献检索和深度分析功能，对膝关节置换后应用药物预防血栓形成的10年文献资料趋势进行多角度探讨分析。
设计：文献计量学分析。
资料提取：以英文“knee arthroplasty/prosthesi (膝关节置换)，thrombosis (血栓)，prevention/prophylaxis (预防)，warfarin (华法林)，low molecular weight heparin/LMWH (低分子肝素)，rivaroxaban (利伐沙班)，aspirin (阿司匹林)”为关键词，检索SCI数据库2001-01/2010-12收录的相关文献，并将分析结果及资料导出，以文字和图表的形式进行统计和计量分析，描述其分布特征。 入选标准：纳入检索的范围为膝关节置换后应用药物预防血栓形成的相关文献。文献类型包括研究原著、综述、会议记录及摘要、快报文章、编辑素材。排除与文章目的无关的文献、大于10年较陈旧的文献、未发表的文章以及需电话追踪和手工检索逐一分析的文献。
主要数据判定指标：以文献的类型、出版时间、来源期刊、学科类别、文献被引情况、国家地区分布、机构分布、发表文献的作者分布以及膝关节置换后应用不同药物预防血栓形成的文献对比进行相关分析。
结果：SCI数据库2001/2010收录膝关节置换后应用药物预防血栓形成相关文献484篇，研究原著391篇居首位，其中6篇文章可以确定为经典文献。文献数量的时间分布上2001/2010呈总体上升趋势，Thrombosis and Haemostasis《血栓形成和止血》杂志发表文献量最多，33篇，占全部文献的6.818%。
结论：通过文献计量学方法对来源于SCI数据库关于膝关节置换术后应用药物预防血栓形成的文献进行分析，可为了解该领域的概貌、现状和进一步研究确定热点提供有价值的数据参考。

关键词: 膝关节置换, 血栓, 预防, 华法林, 低分子肝素, 利伐沙班, 阿司匹林, 文献计量, SCI

Abstract:

BACKGROUND: The application of anticoagulant to prevent thrombosis after knee replacement surgery has become the subject community consensus.
OBJECTIVE: To multivariately analyze the literature on the application of anticoagulant to prevent thrombosis after knee replacement surgery through Science Citation Index Database (SCI) and its analysis tool.
DESIGN: Bibliometric analysis.
DATA RETRIEVAL: A retrieval was performed for the literature of the application of anticoagulant to prevent thrombosis after knee replacement surgery, including knee arthroplasty/prosthesis, thrombosis, prevention/prophylaxis, warfarin, low molecular weight heparin/LMWH, rivaroxaban, aspirin during 2001-01 and 2010-12 in SCI. The retrieval results were analyzed, and the trends were described in words and graphics.
SELECTIVE CRITERIA: Articles on the application of anticoagulant to prevent thrombosis after knee replacement surgery including the following types: (1)Peer-reviewed original paper; (2)Reviews; (3)Meeting notes and abstracts; (4)Letters; (5)Editorial materials. Exclusive criteria were included (1)Articles unrelated the study of the application of anticoagulant to prevent thrombosis after knee replacement surgery. (2)Articles published before 2001. (3)Articles which were not published on journals. (4)Articles which need to be retrieved by phone or manually.
MAIN OUTCOME MEASUREMENTS: The literatures were analyzed by national distribution, publication year, citation frequency, journal distribution, discipline distribution, institutional information and authors.
RESULTS: (1) A total of 484 literatures on the application of anticoagulant to prevent thrombosis after knee replacement surgery were retrieved in SCI database, in which 391 literatures were published as original articles. Six articles were identified as classic literature. The overall number of literature had an upward trend from 2001 to 2010. Thrombosis and Haemostasis published most papers in this field (33 literatures, 6.818%).
CONCLUSION: This paper provides a valuable reference for researchers to understand the overview and present situation of this field in order to set further research.

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