中国组织工程研究

中国组织工程研究 ›› 2012, Vol. 16 ›› Issue (4): 626-629.doi: 10.3969/j.issn.1673-8225.2012.04.013

• 人工假体 artificial prosthesis • 上一篇    下一篇

大直径金属/金属股骨头人工全髋关节置换治疗股骨头缺血坏死**☆

张海宁，吕成昱，徐  浩，王英振   

  1. 青岛大学医学院附属医院关节外科，山东省青岛市  266003
  • 收稿日期:2011-07-13 修回日期:2011-10-31 出版日期:2012-01-22 发布日期:2014-04-04
  • 通讯作者: 王英振，硕士，主任医师，青岛大学医学院附属医院关节外科，山东省青岛市 266003 hunterzhhn@yahoo.com.cn
  • 作者简介:张海宁☆，男，1976年生，山东省潍坊市人，汉族，2005年上海交通大学医学院毕业，博士，副主任医师，硕士生导师，主要从事关节病损的重建修复研究。 zhhaining@hotmail.com
  • 基金资助:

    国家自然科学基金项目(30801167)，课题名称：基于hUCB-MSCs的原位分层多基因增强Mosaicplasty重建大面积骨软骨复合性损伤；国家自然科学基金项目(81171774)，课题名称：siRNA基因沉默与诱导双向基因治疗关节炎的软骨、滑膜生物学响应及ex vivo系统转基因在体示踪研究。

Total hip arthroplasty with large-diameter metal/metal femoral head for treatment of avascular necrosis of the femoral head  

Zhang Hai-ning, Lü Cheng-yu, Xu Hao, Wang Ying-zhen   

  1. Department of Joint Surgery, Affiliated Hospital of Qingdao University, Qingdao  266003, Shandong Province, China
  • Received:2011-07-13 Revised:2011-10-31 Online:2012-01-22 Published:2014-04-04
  • Contact: Wang Ying-zhen, Master, Chief physician, Department of Joint Surgery, Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China hunterzhhn@yahoo.com.cn
  • About author:Wang Ying-zhen, Master, Chief physician, Department of Joint Surgery, Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong Province, China hunterzhhn@yahoo.com.cn
  • Supported by:

    National Natural Science Foundation of China, No. 30801167*, 81171774*

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摘要：

背景：与以往大直径股骨头的高磨损率和高髋臼松动率相比，新一代大直径金属对金属全髋关节有着更长的使用寿命和低磨损，低脱位率等优点。
目的：评价应用大直径金属/金属股骨头人工全髋关节置换术治疗股骨头缺血坏死的临床疗效。
方法：回顾性分析26例股骨头缺血坏死患者实施单侧大直径金属/金属股骨头人工全髋关节置换资料。
结果与结论：所有患者均获得随访，在随访期内影像学显示假体位置良好，无假体松动，脱位等并发症。Harris评分由置换前49.5分改善为置换后92.5分，优良率为96%，总体满意率为96%。置换前后及随访时未发生假体松动、脱位、感染等不良反应。说明大直径金属/金属股骨头全髋关节置换治疗股骨头缺血坏死可获得较好的疗效，短期内无明显肾功能变化。

关键词: 关键词, 金属对金属, 全髋关节置换, 骨坏死, 直径, 影像学

Abstract:

BACKGROUND: The new generation of large-diameter metal has the advantages of longer service life, low abrasion and low dislocation rate in using for metal total hip compared to the high wear rate and high rate of acetabular loosening of previous large-diameter femoral head.
OBJECTIVE: To assess the clinical effects of total hip arthroplasty with large-diameter metal/metal femoral head in treatment of patients with avascular necrosis of the femoral head. 
METHODS: Twenty-six patients with avascular necrosis of femoral head underment unilateral total hip arthroplasty with large-diameter metal/metal femoral head were involved for retrospective analysis.
RESULTS AND CONCLUSION: All patients were followed up. The prosthesis was in the good position, and no loosening of the prosthesis and dislocation were seen by imaging during follow-up. The Harris score was increased from 49.5 before operation to 92.5 after arthroplasty. The excellent and good rate was 96%. The overall satisfaction rate was 96%. There was no prosthesis loosening, dislocation and infection before and after arthroplasty and during the follow-up. Good short-term effects can be obtained from the total hip arthroplasty with large-diameter metal/metal femoral head in treatment of patients with avascular necrosis of the femoral head. No significant changes in renal function of this treatment can be seen in short time.

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