中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (53): 9917-9920.doi: 10.3969/j.issn.1673-8225.2011.53.010

• 肾移植 kidney transplantation • 上一篇    下一篇

脑死亡供肾肾移植受者的近期状况分析

汪帮琦，朱云松，聂海波，赵永斌，胡卫列   

  1. 解放军下尿路疾病诊治中心，解放军广州军区器官移植中心，广东省广州市  510010
  • 收稿日期:2011-06-15 修回日期:2011-09-18 出版日期:2011-12-31 发布日期:2011-12-31
  • 通讯作者: 胡卫列，博士，主任医师，解放军广州军区广州总医院泌尿外科，广东省广州市 510010 huwl-mr@vip.sina.com
  • 作者简介:汪帮琦☆，男，1983年生，安徽省六安市人，汉族，南方医科大学在读博士，医师，主要从事微创在泌尿外科肿瘤中应用的研究。 bangqi916@163.com
  • 基金资助:

    国家自然科学基金项目(30872577)；广东省科技计划项目(2011B031800199)。

Short-term outcomes of renal transplant recipients receiving kidney grafts from brain-death donors

Wang Bang-qi, Zhu Yun-song, Nie Hai-bo, Zhao Yong-bin, Hu Wei-lie   

  1. PLA Center of Diagnosis and Treatment of Lower Urinary Tract Disease, Organ Transplantation Center of Guangzhou Military Region, Guangzhou   510010, Guangdong Province, China
  • Received:2011-06-15 Revised:2011-09-18 Online:2011-12-31 Published:2011-12-31
  • Contact: Hu Wei-lie, Doctor, Chief physician, PLA Center of Diagnosis and Treatment of Lower Urinary Tract Disease, Organ Transplantation Center of Guangzhou Military Region, Guangzhou 510010, Guangdong Province, China huwl-mr@vip.sina. com
  • About author:Wang Bang-qi☆, Studying for doctorate, Physician, PLA Center of Diagnosis and Treatment of Lower Urinary Tract Disease, Organ Transplantation Center of Guangzhou Military Region, Guangzhou 510010, Guangdong Province, China bangqi916@163.com
  • Supported by:

    the National Natural Science Foundation of China, No. 30872577*; the Science and Technology Development Program of Guangdong Province, No. 2011B031800199*

PDF

446

被引次数

2

摘要：

背景：供者短缺严重限制了肾移植的发展，脑死亡供肾在一定程度上缓解了供肾短缺的问题。
目的：比较脑死亡供肾与尸体供肾肾移植患者移植后短期预后情况，初步探讨脑死亡供者在肾移植临床应用中的安全性。
方法：回顾性分析肾移植90例患者移植过程中和移植后情况，其中80例供者为尸体供肾，10例为脑死亡供肾，比较两组受者移植中出血量、手术时间、移植后移植肾功能恢复情况、各种并发症的发生率及移植后近期生存情况(围手术期、移植后6个月)的差异。
结果与结论：两组间移植时间、移植过程中出血量比较差异无显著性意义，移植后1，6个月生存率及移植后并发症的发生率比较，差异亦无显著性意义。说明脑死亡供肾与尸体供肾肾移植患者移植后早期预后无明显差异，安全可靠。

关键词: 肾移植, 供者, 脑死亡供肾, 尸体供肾, 预后

Abstract:

BACKGROUND: The shortage of donors has severely limited the development of renal transplantation. However, brain-death donors can alleviate the problem of renal transplantation donor shortage to some extent.
OBJECTIVE: To compare the short-term outcomes of renal transplantation recipients receiving kidney grafts from brain-death and cadaveric brainstem dead donors and evaluate the safety of kidney grafts from brain-death donors.
METHODS: A total of 90 patients receiving renal transplantation were retrospectively analyzed, including 10 patients receiving kidney graft from brain-death donors and 80 with grafts from cadaveric brainstem dead donors. The operative time, bleeding volume, postoperative complications and short-term survival were compared between the two groups.
RESULTS AND CONCLUSION: The operative time, bleeding volume, postoperative complications and short-term survival showed no significant differences between the two groups. The short-term outcome of recipients receiving kidney grafts from brain-death donors is similar to that of recipients receiving grafts from cadaveric brainstem dead donors, indicating the safety of clinical use of the kidney grafts from brain-death donors.

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