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文题释义：
软骨肉瘤：是一种来源于透明软骨的恶性肿瘤，在原发性骨恶性肿瘤中排名第二，仅次于骨肉瘤。软骨肉瘤可以发生在任何骨骼中，但常见于骨盆、肱骨、股骨、肩胛骨和肋骨，并且可出现在任何年龄，高级别软骨肉瘤患者的死亡率很高。
微小RNA(miRNA)：是一类长19-25个碱基的内源性非蛋白编码RNA，具有高度保守性。它主要通过与靶基因mRNA的3’非翻译区(3’-UTR)结合，降解mRNA靶基因或诱导翻译沉默，从而发挥调控细胞增殖、分化、凋亡、个体发育等作用。miRNA具有高度保守性，因此其转录过程与其他基因相互独立，在生物体内多种代谢过程中发挥调控作用，本身并不翻译蛋白质。
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.jpg)
文题释义：
软骨肉瘤：是一种来源于透明软骨的恶性肿瘤，在原发性骨恶性肿瘤中排名第二，仅次于骨肉瘤。软骨肉瘤可以发生在任何骨骼中，但常见于骨盆、肱骨、股骨、肩胛骨和肋骨，并且可出现在任何年龄，高级别软骨肉瘤患者的死亡率很高。
微小RNA(miRNA)：是一类长19-25个碱基的内源性非蛋白编码RNA，具有高度保守性。它主要通过与靶基因mRNA的3’非翻译区(3’-UTR)结合，降解mRNA靶基因或诱导翻译沉默，从而发挥调控细胞增殖、分化、凋亡、个体发育等作用。miRNA具有高度保守性，因此其转录过程与其他基因相互独立，在生物体内多种代谢过程中发挥调控作用，本身并不翻译蛋白质。