中国组织工程研究

中国组织工程研究 ›› 2011, Vol. 15 ›› Issue (42): 7877-7880.doi: 10.3969/j.issn.1673-8225.2011.42.021

• 膜生物材料 membrane biomaterials • 上一篇    下一篇

壳聚糖/介孔生物活性玻璃多孔膜的制备和表征

贾天保1，陈建勇1，冯新星1, 2，常  江2   

  1. 1浙江理工大学“先进纺织材料与制备技术”教育部重点实验室，材料与纺织学院，浙江省杭州市   310018
    2中国科学院上海硅酸盐研究所，上海市   200050
  • 收稿日期:2011-04-06 修回日期:2011-06-15 出版日期:2011-10-15 发布日期:2011-10-15
  • 通讯作者: 冯新星，博士，副教授，硕士生导师，浙江理工大学材料与纺织学院，浙江省杭州市 310018 fengxx@ zstu.edu.cn
  • 作者简介:贾天保★，男，1986年生，河南省鹤壁市人，浙江理工大学在读硕士，主要从事功能材料、生物材料的研究。 jiatianbao_01@ 126.com
  • 基金资助:

    国家自然科学基金项(50973096, 50903073, 31070867)；浙江省科技厅公益项目(2010C31038)。

Fabrication and characterization of chitosan/mesoporous bioactive glasses porous films

Jia Tian-bao1, Chen Jian-yong1, Feng Xin-xing1, 2, Chang Jiang2   

  1. 1Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textiles, Zhejiang Sci-Tech University, Hangzhou  310018, Zhejiang Province, China
    2Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai  200050, China
  • Received:2011-04-06 Revised:2011-06-15 Online:2011-10-15 Published:2011-10-15
  • Contact: Feng Xin-xing, Doctor, Associate professor, Master’s supervisor, Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textiles, Zhejiang Sci-Tech University, Hangzhou 310018, Zhejiang Province, China; Shanghai Institute of Ceramics, Chinese Academy of Sciences, Shanghai 200050, China fengxx@zstu.edu.cn
  • About author:Jia Tian-bao★, Studying for master’s degree, Key Laboratory of Advanced Textile Materials and Manufacturing Technology of Ministry of Education, College of Materials and Textiles, Zhejiang Sci-Tech University, Hangzhou 310018, Zhejiang Province, China jiatianbao_01@ 126.com
  • Supported by:

    the National Natural Science Foundation of China, No. 50973096*, 50903073*, 31070867*; Commonweal Project of Science and Technology Department of Zhejiang Province, No. 2010C31038*

PDF

479

被引次数

2

摘要：

背景：壳聚糖和介孔生物玻璃都具有良好的生物相容性和止血性能，但壳聚糖止血作用有限，介孔生物玻璃粉体方式止血，给应用带来不便。
目的：制备壳聚糖/介孔生物玻璃复合多孔膜并检测材料的性能。
方法：采用冷冻干燥法制备壳聚糖/介孔生物玻璃复合多孔膜。
结果与结论：通过冷冻干燥法可以实现壳聚糖和介孔生物玻璃的均匀复合。制备的复合多孔膜的孔隙分布较均匀；多孔膜具有很好的吸水性，吸水率的大小与壳聚糖和介孔生物玻璃质量比相关；多孔膜的孔隙率高。

关键词: 介孔生物玻璃, 壳聚糖, 冷冻干燥, 多孔膜, 止血

Abstract:

BACKGROUND: Chitosan (CS) and mesoporous bioactive glasses (MBG) have some good properties, such as biocompatibility and hemostasis, but the hemostatic effect of CS is limited and it is inconvenient to use the MBG directly.
OBJECTIVE: To prepare CS/MBG porous films
METHODS: CS and MBG porous film was prepared through a freeze drying process. The prepared porous films were characterized by using Fourier transform infrared spectroscopy, scanning electron microscope and X-ray diffraction. In addition, water adsorption, swelling ratio, the porosity and the mechanical property of the porous films were also studied.
RESLUTS AND CONCLUSION: CS/MBG could be blended homogeneously via the lyophilization. The hole of the porous films was relatively uniform. The porous films showed good water adsorption character, which could be modulated by varying the weight ratio of CS and MBG. The prepared porous films had a higher porosity. The composite films can be potentially applied as a wound dressing material.

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